Impatiens necrotic spot orthotospovirus (INSV) is a plant pathogenic virus of the order Bunyavirales. It was originally believed to be another strain of Tomato spotted wilt virus, but genetic investigations revealed them to be separate viruses. It is a negative-strand RNA virus which has a tripartite genome. It is largely spread by the insect vector of the western flower thrips. The virus infects more than 648 species of plants including important horticultural and agricultural species such as fuchsia, tomato, orchids, and lettuce (especially romaine). As the name implies, the main symptom on plants is necrotic spots that appear on the leaves. The INSV virus infects by injecting the RNA the virus contains into the cell which then starts using the cell resources to transcribe what the virus RNA states. Viral infection can often result in the death of the plant. The disease is mainly controlled by the elimination of the western flower thrip vector and by destroying any infected plant material. Disease cycle The disease is an ssRNA that injects itself into the host cell, then has the host cell duplicate the RNA sequence as well as the coat protein used to disguise the RNA. The infected cell also starts to create movement proteins that facilitate the movement of the virus through the plant making the plasmodesmata (connections between plant cells) large enough to allow the virus to move throughout the plant. The virus can then also infect other plants by either the infected sap or a vector, such as an insect, which will start the cycle over again. Management Typically the best way to manage a virus problem is to get rid of any vectors that may carry the disease. This easily can be done by an insecticide. Another acceptable method would be resistance plants. These plants would kill off any infected cells, not allowing the virus to spread. Furthermore, larger distance between plants could help the spread of the disease not allowing the virus to be transmitted virtually. This can be done by controlling weeds and thrips, the most common vector transmission. Chemical controls of herbicides and insecticides can be implemented and is the best form of control. If virus remains a problem, other plants can be planted in that area that do not have the traits required for infection of INSV. Hosts and symptoms INSV has a wide host range and can be found in over 300