(10) || Dessens (3-5) || Roney (0-1) || Burgos (7) || 12,516 || 23-29 |- style="background-color:#bbffbb" | 53 || May 31 || Royals || 7-0 || Blanton (5-5) || Elarton (1-6) || – || 25,181 || 24-29 |- style="background-color:#bbffbb" | 54 || June 1 || Twins || 4-0 || Zito (5-3) || Bonser (1-1) || – || 12,025 || 25-29 |- style="background-color:#ffbbbb" | 55 || June 2 || Twins || 1-2 || Santana (5-4) || Saarloos (2-4) || Nathan (7) || 16,138 || 25-30 |- style="background-color:#bbffbb" | 56 || June 3 || Twins || 2-1 || Halsey (2-2) || Radke (4-7) || Street (9) || 23,194 || 26-30 |- style="background-color:#bbffbb" | 57 || June 4 || Twins || 5-1 || Halsey (3-2) || Silva (2-7) || – || 25,247 || 27-30 |- style="background-color:#bbffbb" | 58 || June 6 || @ Indians || 7-6 || Zito (6-3) || Betancourt (0-1) || Street (10) || 17,340 || 28-30 |- style="background-color:#ffbbbb" | 59 || June 7 || @ Indians || 2-11 || Byrd (5-4) || Blanton (5-6) || – || 20,311 || 28-31 |- style="background-color:#bbffbb" | 60 || June 8 || @ Indians || 4-1 || Loaiza (1-3) || Johnson (3-6) || Street (11) || 21,099 || 29-31 |- style="background-color:#bbffbb" | 61 || June 9 || @ Yankees || 6-5 || Haren (5-5) || Johnson (7-5) || Street (12) || 53,837 || 30-31 |- style="background-color:#bbffbb" | 62 || June 10 || @ Yankees || 5-2 || Saarloos (3-4) || Mussina (8-2) || Street (13) || 53,779 || 31-31 |- style="background-color:#bbffbb" | 63 || June 11 || @ Yankees || 6-5 || Zito (7-3) || Kyle Farnsworth (2-4) || Street (14) || 54,570 || 32-31 |- style="background-color:#bbffbb" | 64 || June 13 || Mariners || 2-0 || Blanton (6-6) || Moyer (3-6) || Street (15) || 15,216 || 33-31 |- style="background-color:#bbffbb" | 65 || June 14 || Mariners || 7-2 || Haren (6-5) || Piñeiro (5-7) || – || 20,550 || 34-31 |- style="background-color:#bbffbb" | 66 || June 15 || Mariners || 9-6 || Loaiza (2-3) || Washburn (4-8) || Street (16) || 16,563 || 35-31 |- style="background-color:#bbffbb" | 67 || June 16 || Dodgers || 7-3 || Zito (8-3) || Tomko (5-6) || – || 30,161 || 36-31 |- style="background-color:#bbffbb" | 68 || June 17 || Dodgers || 5-4 (17) || Karsay (1-0) || Seo (2-4) || – || 35,077 || 37-31 |-