Leonard (0-1) || Rodríguez (3) || Milwaukee County Stadium || 4,902 || 3-5 || L2 |- style="background:#bfb;" | 9 || April 22 || @ Brewers || 2–1 || Bird (1-0) || Colborn (1-1) || || Milwaukee County Stadium || 5,196 || 4-5 || W1 |- style="background:#bfb;" | 10 || April 23 || @ Yankees || 3–2 || Splittorff (1-2) || Hunter (1-3) || Mingori (1) || Yankee Stadium || 35,116 || 5-5 || W2 |- style="background:#fbb;" | 11 || April 24 || @ Yankees || 8–9 (11) || Lyle (2-0) || Pattin (0-2) || || Yankee Stadium || 16,034 || 5-6 || L1 |- style="background:#fbb;" | 12 || April 30 || Yankees || 3–5 || Hunter (2-3) || Splittorff (1-3) || || Royals Stadium || 11,368 || 5-7 || L2 |- style="background:#bfb;" | 13 || May 1 || Yankees || 4–1 || Busby (1-1) || Figueroa (1-1) || || Royals Stadium || 18,703 || 6-7 || W1 |- style="background:#bfb;" | 14 || May 2 || Yankees || 2–1 (11) || Bird (2-0) || Lyle (1-1) || || Royals Stadium || 13,404 || 7-7 || W2 |- style="background:#bfb;" | 15 || May 4 || @ Red Sox || 7–5 || Fitzmorris (3-0) || Lee (0-3) || Bird (1) || Fenway Park || 16,274 || 8-7 || W3 |- style="background:#bfb;" | 16 || May 5 || @ Red Sox || 8–4 || Splittorff (2-3) || Jenkins (1-4) || Littell (1) || Fenway Park || 17,596 || 9-7 || W4 |- style="background:#fbb;" | 17 || May 7 || @ Orioles || 3–4 || Garland (2-0) || Pattin (0-3) || || Memorial Stadium || 7,310 || 9-8 || L1 |- style="background:#bfb;" | 18 || May 8 || @ Orioles || 6–3 || Leonard (1-1) || Holtzman (2-2) || Bird (2) || Memorial Stadium || 51,195 || 10-8 || W1 |- style="background:#bfb;" | 19 || May 9 || @ Orioles || 7–4 || Littell (1-0) || Palmer (4-4) || || Memorial Stadium || 7,590 || 11-8 || W2 |- style="background:#fbb;" | 20 || May 10 || Twins || 4–5 (10) || Burgmeier (2-0) || Pattin (0-4) || Luebber (2) || Royals Stadium || 12,526 || 11-9 || L1 |- style="background:#bfb;" | 21 || May 11 || Twins || 6–3 || Bird (3-0) || Luebber (0-1) || Littell (2) || Royals Stadium || 9,652 || 12-9 || W1 |- style="background:#bfb;" | 22 || May 12 ||