entered into force in 2005. FCTC marked a milestone as the first international treaty concerning a global health issue that aims to combat tobacco in multiple aspects including tobacco taxes, advertisement, trading, environmental affects, health influences, etc. The birth of this evidence-based and systematic approach has resulted in the reinforcement of tobacco taxes and the implementation of smoke-free laws in 128 countries that led to the decrease of smoking prevalence in developing nations. Other substances In the early 1980s, organized international trafficking of cocaine grew. However, overproduction and tighter legal enforcement for the illegal product caused drug dealers to convert the powder to "crack" – a solid, smokable form of cocaine that could be sold in smaller quantities to more people. This trend abated in the 1990s as increased police action coupled with a robust economy caused many potential consumers to give up or fail to take up the habit. Recent years shows an increase in the consumption of vaporized heroin, methamphetamine and Phencyclidine (PCP). Along with a smaller number of psychedelic drugs such as Changa, DMT, 5-Meo-DMT, and Salvia divinorum. Substances and equipment The most popular type of substance that is smoked is tobacco. There are many different tobacco cultivars which are made into a wide variety of mixtures and brands. Tobacco is often sold flavored, often with various fruit aromas, something which is especially popular for use with water pipes, such as hookahs. The second most common substance that is smoked is cannabis, made from the flowers or leaves of Cannabis sativa or Cannabis indica. The substance is considered illegal in most countries in the world and in the countries that tolerate public consumption, it is sometimes only pseudo-legal. Despite this, a considerable percentage of the adult population in many countries have tried it with smaller minorities doing it on a regular basis. Since cannabis is illegal or only tolerated in many jurisdictions, there is no industrial mass-production of cigarettes, meaning that the most common form of smoking is with hand-rolled cigarettes (often called joints) or with pipes. Water pipes are also fairly common; water pipes used for cannabis include designs known as bongs and bubblers, among others. A few other recreational drugs are smoked by smaller minorities. Most of these substances are controlled, and some are considerably more intoxicating than either tobacco or cannabis. These include crack cocaine, heroin, methamphetamine and PCP. A small number of psychedelic