|| August 11 || @ Angels || 8–10 || Weber (3–1) || Colón (10–10) || || 3:13 || 35,889 || 62–56 || box |- style="text-align:center;background-color:#bbffbb" | 119 || August 12 || @ Angels || 10–4 || Wright (1–5) || Ortiz (13–10) || || 3:17 || 36,458 || 63–56 || box |- style="text-align:center;background-color:#ffbbbb" | 120 || August 13 || @ Angels || 1–2 || Rodríguez (6–2) || Buehrle (10–12) || Percival (24) || 2:27 || 37,563 || 63–57 || box |- style="text-align:center;background-color:#ffbbbb" | 121 || August 14 || @ Angels || 1–5 || Shields (3–3) || Garland (8–9) || Percival (25) || 2:46 || 35,056 || 63–58 || box |- style="text-align:center;background-color:#ffbbbb" | 122 || August 15 || @ Rangers || 5–11 || Lewis (6–7) || Loaiza (15–6) || || 2:46 || 21,186 || 63–59 || box |- style="text-align:center;background-color:#ffbbbb" | 123 || August 16 || @ Rangers || 8–12 || Benoit (8–5) || Colón (10–11) || || 2:50 || 40,072 || 63–60 || box |- style="text-align:center;background-color:#ffbbbb" | 124 || August 17 || @ Rangers || 4–6 || Powell (3–0) || Marte (4–2) || Cordero (11) || 2:46 || 17,015 || 63–61 || box |- style="text-align:center;background-color:#bbffbb" | 125 || August 18 || Angels || 4–2 || Gordon (6–5) || Washburn (9–12) || || 2:07 || 32,381 || 64–61 || box |- style="text-align:center;background-color:#bbffbb" | 126 || August 19 || Angels || 5–2 || Garland (9–9) || Shields (3–4) || Gordon (7) || 2:31 || 22,396 || 65–61 || box |- style="text-align:center;background-color:#bbffbb" | 127 || August 20 || Angels || 5–3 || Loaiza (16–6) || Lackey (8–12) || Marte (10) || 2:49 || 17,879 || 66–61 || box |- style="text-align:center;background-color:#bbffbb" | 128 || August 21 || Rangers || 7–3 || Colón (11–11) || Lewis (6–8) || Gordon (8) || 2:48 || 18,305 || 67–61 || box |- style="text-align:center;background-color:#bbffbb" | 129 || August 22 || Rangers || 7–1 || Cotts (1–0) || Dominguez (0–2) || || 2:34 || 36,311 || 68–61 || box |- style="text-align:center;background-color:#bbffbb" | 130 || August 23 || Rangers || 13–2 || Buehrle (11–12) || Valdez (7–8) || Wright (1) || 2:22 || 33,721 || 69–61 || box |- style="text-align:center;background-color:#ffbbbb" | 131 || August 24 || Rangers || 0–5 || Thomson (12–10) || Garland (9–10) || || 2:26 || 29,364 || 69–62 || box |- style="text-align:center;background-color:#bbffbb" | 132 || August 26 || @ Yankees || 13–2 || Loaiza (17–6) || Clemens (12–8) ||