Twins || 2–9 || Aguilera || Oliver (10–6) || — || 16,166 || 74–55 |- bgcolor="ffbbbb" | 131 || August 24 || @ Twins || 5–6 || Rodriguez || Pavlik (14–7) || Trombley || 16,648 || 74–56 |- bgcolor="ccffcc" | 132 || August 25 || @ Twins || 13–2 || Witt (13–9) || Miller || — || 14,818 || 75–56 |- bgcolor="ffbbbb" | 133 || August 27 || @ Royals || 3–4 (10) || Montgomery || Russell (3–3) || — || 12,907 || 75–57 |- bgcolor="ffbbbb" | 134 || August 28 || @ Royals || 3–4 (12) || Huisman || Gross (10–8) || — || 12,695 || 75–58 |- bgcolor="ccffcc" | 135 || August 30 || Indians || 5–3 || Pavlik (15–7) || Ogea || Russell (3) || 40,383 || 76–58 |- bgcolor="ccffcc" | 136 || August 31 || Indians || 6–3 || Oliver (11–6) || McDowell || Vosberg (7) || 46,319 || 77–58 |- |- bgcolor="ffbbbb" | 137 || September 1 || Indians || 2–8 || Nagy || Burkett (2–1) || — || 46,084 || 77–59 |- bgcolor="ffbbbb" | 138 || September 2 || Twins || 4–6 || Aguilera || Hill (14–8) || Guardado || 24,786 || 77–60 |- bgcolor="ccffcc" | 139 || September 3 || Twins || 9–7 || Witt (14–9) || Rodriguez || Henneman (27) || 28,401 || 78–60 |- bgcolor="ffbbbb" | 140 || September 4 || Twins || 6–7 || Robertson || Heredia (2–5) || Trombley || 29,744 || 78–61 |- bgcolor="ccffcc" | 141 || September 6 || @ Brewers || 7–3 || Burkett (3–1) || Eldred || — || 16,714 || 79–61 |- bgcolor="ccffcc" | 142 || September 7 || @ Brewers || 2–1 || Hill (15–8) || McDonald || Henneman (28) || 19,110 || 80–61 |- bgcolor="ccffcc" | 143 || September 8 || @ Brewers || 7–1 || Witt (15–9) || Florie || — || 17,542 || 81–61 |- bgcolor="ccffcc" | 144 || September 9 || @ Blue Jays || 4–3 || Gross (11–8) || Hentgen || Henneman (29) || 25,825 || 82–61 |- bgcolor="ccffcc" | 145 || September 10 || @ Blue Jays || 11–8 || Oliver (12–6) || Williams || Henneman (30) || 26,286 || 83–61 |- bgcolor="ffbbbb" | 146 || September 11 || @ Blue Jays || 3–8 || Andujar || Vosberg (1–1) || — || 27,262 || 83–62 |- bgcolor="ffbbbb" | 147 || September 12 || Brewers || 4–15 ||