2:15 || 3,813 || 6–9 || L1 |- style="background:#fcc;" | 16 || April 22 || 8:05p.m. EST || Tigers || L 2–4 || Hiller (1–0) || Pascual (0–3) || McMahon (3) || 2:48 || 4,922 || 6–10 || L2 |- style="background:#bbb;" |–|| April 24 || || @ Red Sox || colspan="8"|Postponed (Rain) |- style="background:#cfc;" | 21 || April 28 || 8:00p.m. EDT || @ Tigers || W 6–1 || Pascual (1–3) || Wilson (1–3) || Bosman (1) || 2:39 || 7,353 || 11–10 || W5 |- style="background:#fcc;" | 22 || April 29 || 8:00p.m. EDT || @ Tigers || L 4–5 || Radatz (1–0) || Bertaina (1–2) || – || 2:24 || 6,986 || 11–11 || L1 |- |- |- style="background:#bbb;" |–|| June 15 || || Angels || colspan="8"|Postponed (Rain) |- style="background:#fcc;" | 64 || June 17 || 8:05p.m. EDT || Orioles || L 1–5 || Cuellar (0–2) || Shellenback (1–2) || – || 2:26 || 22,134 || 31–33 || L2 |- style="background:#fcc;" | 65 || June 18 || 8:05p.m. EDT || Orioles || L 1–3 || Hardin (3–3) || Moore (5–2) || Hall (2) || 2:11 || 10,420 || 31–34 || L3 |- style="background:#fcc;" | 66 || June 19 || 8:05p.m. EDT || Orioles || L 0–2 || McNally (10–0) || Higgins (4–7) || – || 2:04 || 13,376 || 31–35 || L4 |- style="background:#cfc;" | 67 || June 20 || 8:00p.m. EDT || @ Tigers || W 7–2 || Knowles (3–0) || McMahon (1–4) || – || 3:07 || 27,725 || 32–35 || W1 |- style="background:#fcc;" | 68 || June 21 || 1:15p.m. EDT || @ Tigers || L 5–9 || Lolich (8–1) || Humphreys (1–2) || – || 2:31 || 25,340 || 32–36 || L1 |- style="background:#cfc;" | 69 || June 22 || 1:30p.m. EDT || @ Tigers || W 9–4 || Higgins (5–7) || Dobson (2–5) || – || 2:51 || – || 33–36 || W1 |- style="background:#cfc;" | 70 || June 22 || 4:56p.m. EDT || @ Tigers || W 9–5 || Moore (6–2) || Sparma (4–3) || – || 1:51 || 52,721 || 34–36 || W2 |- style="background:#fcc;" | 71 || June 23 || 8:00p.m. EDT || @ Orioles || L 3–5 || Palmer (9–2) || Knowles (3–1) || Richert (6) || 1:57 || 7,830 || 34–37 || L1 |- style="background:#fcc;" | 72 || June 24 || 8:00p.m. EDT || @ Orioles || L