|| Mesa || 43,299 || 27–16 |- bgcolor="ffbbbb" | 44 || May 21 || @ Twins || 3–4 || Milchin || Henneman (0–2) || — || 12,323 || 27–17 |- bgcolor="ccffcc" | 45 || May 22 || @ Twins || 6–5 || Pavlik (6–1) || Parra || Henneman (12) || 17,955 || 28–17 |- bgcolor="ffbbbb" | 46 || May 23 || @ Royals || 2–4 || Appier || Oliver (3–2) || Montgomery || 15,612 || 28–18 |- bgcolor="ffbbbb" | 47 || May 24 || @ Royals || 0–8 || Gubicza || Witt (4–4) || — || 13,696 || 28–19 |- bgcolor="ccffcc" | 48 || May 25 || @ Royals || 2–1 || Helling (1–1) || Haney || Henneman (13) || 23,668 || 29–19 |- bgcolor="ccffcc" | 49 || May 26 || @ Royals || 6–4 || Hill (6–3) || Linton || Henneman (14) || 22,665 || 30–19 |- bgcolor="ccffcc" | 50 || May 27 || Indians || 3–2 || Pavlik (7–1) || McDowell || — || 46,521 || 31–19 |- bgcolor="ccffcc" | 51 || May 28 || Indians || 11–3 || Oliver (4–2) || Hershiser || — || 35,727 || 32–19 |- bgcolor="ccffcc" | 52 || May 29 || Indians || 5–4 || Cook (3–0) || Tavarez || Henneman (15) || 35,893 || 33–19 |- bgcolor="ccffcc" | 53 || May 31 || Twins || 7–2 || Hill (7–3) || Rodriguez || — || 32,861 || 34–19 |- |- bgcolor="ffbbbb" | 54 || June 1 || Twins || 5–9 || Milchin || Henneman (0–3) || — || 43,413 || 34–20 |- bgcolor="ffbbbb" | 55 || June 2 || Twins || 5–6 || Guardado || Russell (1–1) || — || 33,809 || 34–21 |- bgcolor="ccffcc" | 56 || June 3 || @ Brewers || 9–6 || Witt (5–4) || Sparks || Henneman (16) || 9,748 || 35–21 |- bgcolor="ffbbbb" | 57 || June 4 || @ Brewers || 2–6 || Bones || Gross (5–4) || — || 10,685 || 35–22 |- bgcolor="ffbbbb" | 58 || June 5 || @ Brewers || 4–6 || McDonald || Hill (7–4) || Fetters || 11,276 || 35–23 |- bgcolor="ccffcc" | 59 || June 7 || Blue Jays || 10–7 || Pavlik (8–1) || Janzen || Henneman (17) || 40,046 || 36–23 |- bgcolor="ccffcc" | 60 || June 8 || Blue Jays || 2–0 || Oliver (5–2) || Guzman || — || 43,439 || 37–23 |- bgcolor="ccffcc"