the first 100-yard rushing game of his NFL career, rushing 16 times for 111 yards and a touchdown in a 40-14 win for the Bills. Spiller finished the year with 561 yards on 107 carries, with 4 rushing touchdowns and a 5.2 yards/carry average. He also recorded 39 receptions for 269 yards and 2 touchdowns. 2012 season With Fred Jackson once again missing time due to injuries, Spiller took advantage of the opportunity to have a career year. In Week 15 against the Seattle Seahawks, Spiller reached the 1,000 yards rushing mark for the first time in his NFL career. He also only needed 154 carries to reach the mark - the fewest carries to 1,000 yards since Chicago Bears running back Beattie Feathers in 1934. Spiller rushed for 1,244 yards on only 207 carries and scored 6 touchdowns; his (6.009) yards per carry average (YPC) was second to Adrian Peterson's (6.025). He also caught 43 passes for 459 yards with two receiving touchdowns. Spiller was also elected to be in the Pro Bowl as an alternate for Baltimore Ravens running back Ray Rice, who participated in the Super Bowl. 2013 season On August 27, 2013, Spiller took temporary leave from active status with the Bills to be with his family after the murder–suicide by his step-grandfather Hubert Allen, Jr. In 2013, Spiller rushed for 933 yards with 185 receiving yards in 15 games (10 starts). 2014 season In Week 2 against the Miami Dolphins, Spiller returned a kickoff for a touchdown going 102 yards. For his efforts beyond that, Spiller was named the AFC Special Teams Player of the Week. On October 19, Spiller broke his collarbone against the Minnesota Vikings. He was placed on injured reserve/designated to return on October 21, 2014. He returned to action against the Raiders in Week 16. The 2014 season was a tumultuous year for the Bills' running backs, aside from Spiller's injury. Fellow running back Fred Jackson was also injured, leaving newly signed backs Anthony Dixon and Bryce Brown as the only healthy running backs for much of the season. New Orleans Saints On March 13, 2015, Spiller signed a four-year, $18 million contract with the New Orleans Saints. The deal included $9 million guaranteed. In a Week 4 game against the Dallas Cowboys, Spiller caught an 80-yard touchdown pass in overtime to win. It was Saints quarterback Drew Brees' 400th career