The San Angelo metropolitan statistical area (MSA) is a metropolitan area in West Texas that covers two counties - Tom Green and Irion. As of the 2010 census, the MSA had a population of 111,823, with a 2014 estimate of 118,182. Counties Irion Tom Green Communities Cities San Angelo (principal city) Mertzon Census-designated places Christoval Grape Creek Unincorporated places Barnhart Carlsbad Knickerbocker Sherwood Tankersley Vancourt Veribest Wall Water Valley Demographics As of the census of 2020, 122,888 people, 47,794 households, and 28,198 families were residing within the MSA. The racial makeup of the MSA was 65.8% White (non-Hispanic White 52.4%), 3.7% African American, 0.9% Native American, 1.5% Asian, and 17.6% from other races. Hispanics or Latinos of any race were 38.9% of the population. See also List of cities in Texas List of museums in West Texas Texas census statistical areas List of Texas metropolitan areas References Geography of Tom Green County, Texas Geography of Irion County, Texas