|| Maddux || || 39,269 || 95–55 |- bgcolor=#ffbbbb | 151 || September 18 || @ Cubs || 4–7 || Zambrano || Reyes || || 38,182 || 95–56 |- bgcolor=#ffbbbb | 152 || September 20 || @ Reds || 5–6 || Hancock || King || Weathers || 16,587 || 95–57 |- bgcolor=#ccffcc | 153 || September 21 || @ Reds || 5–1 || Marquis || Ortiz || || 16,784 || 96–57 |- bgcolor=#ffbbbb | 154 || September 22 || @ Reds || 2–6 || Coffey || King || || 17,461 || 96–58 |- bgcolor=#ffbbbb | 155 || September 23 || @ Brewers || 6–9 || Capuano || Carpenter || Turnbow || 22,472 || 96–59 |- bgcolor=#ffbbbb | 156 || September 24 || @ Brewers || 7–8 || Glover || Mulder || Turnbow || 33,506 || 96–60 |- bgcolor=#ccffcc | 157 || September 25 || @ Brewers || 2–0 || Suppan || Davis || Isringhausen || 20,150 || 97–60 |- bgcolor=#ffbbbb | 158 || September 27 || Astros || 1–3 || Oswalt || Morris || Lidge || 40,260 || 97–61 |- bgcolor=#ffbbbb | 159 || September 28 || Astros || 6–7 || Qualls || Isringhausen || Lidge || 40,616 || 97–62 |- bgcolor=#ccffcc | 160 || September 30 || Reds || 12–6 || Reyes || Hudson || || 47,257 || 98–62 |- |- bgcolor=#ccffcc | 161 || October 1 || Reds || 9–6 || Flores || Simpson || Isringhausen || 49,487 || 99–62 |- bgcolor=#ccffcc | 162 || October 2 || Reds || 7–5 || Thompson || Claussen || Isringhausen || 50,434 || 100–62 |- Postseason Game Log |- bgcolor=#ccffcc | 1 || October 4 || Padres || 8–5 || Carpenter || Peavy || || 52,349 || 1–0 |- bgcolor=#ccffcc | 2 || October 6 || Padres || 6–2 || Mulder || Astacio || || 52,599 || 2–0 |- bgcolor=#ccffcc | 3 || October 8 || @ Padres || 7–4 || Morris || W. Williams || Isringhausen || 45,093 || 3–0 |- |- bgcolor=#ccffcc | 1 || October 12 || Astros || 5–3 || Carpenter || Pettitte || Isringhausen || 52,332 || 1–0 |- bgcolor=#ffbbbb | 2 || October 13 || Astros || 1–4 || Oswalt || Mulder || Lidge || 52,358 || 1–1 |- bgcolor=#ffbbbb | 3 || October 15 || @ Astros || 3–4 || Clemens || Morris || Lidge || 42,823 || 1–2 |- bgcolor=#ffbbbb | 4 ||