not likely under any feasible scenario (five were modeled). The parallel to the overharvesting of Swietenia macrophylla (big-leaf mahogany), a tree that grows in a similar distribution in the same areas as ipê, is interesting, yet ipê continues to be logged at prodigious rates with no sign of a listing in the Convention on Trade in International Species or other drastic actions likely necessary to prevent extinction. Swietenia mahagoni and Swietenia humilis (other species yielding mahogany wood) were so thoroughly depleted that by the early 1900s there were essentially none left to harvest in the wild. Unfortunately the current scenario is one in which Handroanthus is headed for similar unsustainable depletion of wild populations. Uses It is used as a honey plant, and widely planted as an ornamental tree in landscaping gardens, public squares and boulevards due to its impressive and colorful appearance as it flowers. Well-known and popular, it is the national tree of Paraguay. It is also planted as a street tree in cities of India, like in Bangalore. The inner bark is used in traditional medicine. It is dried, shredded, and then boiled, making a bitter brownish-colored tea known as lapacho or taheebo. The unpleasant taste of the extract is lessened when taken in pill form, or as tinctures. Lapacho bark is typically used during flu and cold season and for easing smoker's cough. It is claimed to work by promoting the lungs to expectorate and free deeply embedded mucus and contaminants during the first three to ten days of treatment. In ethnomedicine, lapacho plays an important role for several South American indigenous people. In the past decades it has been used by herbalists as a general tonic, immunostimulant, and adaptogen. It is used in herbal medicine for intestinal candidiasis. However, the main active compound lapachol has since turned out to be toxic enough to kill fetuses in pregnant rats and reduce the weight of the seminal vesicle in male rats in doses of 100 mg/kg of body weight. Still, lapachol has strong antibiotic and disinfectant properties, and may be better suited for topical applications. Lapachol induces genetic damage, specifically clastogenic effects, in rats. Beta-lapachone has a direct cytotoxic effect and the loss of telomerase activity in leukemia cells in vitro. The ethnomedical use of lapacho and other Handroanthus teas is usually short-term, to get rid of acute ailments, and not as a general tonic. Usefulness as