Cranberry juice is the liquid juice of the cranberry, often manufactured to contain sugar, water, and other fruit juices—especially when labeled as 'Cranberry Cocktail'. Cranberry—a fruit native to North America—is recognized for its bright red color, tart taste, and versatility for product manufacturing. Major cranberry products include cranberry juice, dried cranberry, cranberry sauce, frozen cranberry, cranberry powder, and dietary supplements containing cranberry extracts. The term "cranberry juice cocktail" or "cranberry juice blend" refers to products that contain about 28% cranberry juice, with the remainder either from other fruit juice concentrates (typically grape, apple or pear), water, and added sugar to improve palatability. Low-calorie cranberry juice products use non-caloric sweeteners. The tartness of cranberry juice derives from its mixed content of polyphenols, including flavonoids, proanthocyanidins, anthocyanins, phenolic acids, and ellagitannins. Despite a long-held reputation for providing antibacterial activity against urinary tract infections (UTIs), cranberry juice has no such proven effects, as determined by a Cochrane review of completed clinical research and a scientific panel for the European Food Safety Authority which concluded a cause-and-effect relationship could not be established between cranberry consumption and risk of UTIs. Nutrition and composition Cranberry juice is 86% water, 11% carbohydrates, and less than 1% fat or protein (table). A cup of standard (fortified) cranberry juice, amounting to 248 grams or 8 ounces, provides 107 calories and contains vitamin C as an ingredient to preserve freshness, with other micronutrients that may be added during manufacturing. Other than vitamin C and folate having more than 10% of the Daily Value, a typical serving of cranberry juice provides no micronutrients in significant content (table). One half cup of cranberry juice provides 60 calories, 20% of the Daily Value for vitamin C, and counts as one-half of a fruit serving toward the United States MyPlate daily nutrition guide. Effect on health Cranberry juice is an acidic drink with a pH of about 2.6. Some cranberry juice products contain large amounts of sugar used in manufacturing to make the drink more palatable, but their consumption may increase the risk of hyperglycemia and reduced control of blood glucose in people with diabetes or glucose intolerance. Cranberry juice and urinary tract infection In 2008, there was tentative evidence that long-term use of cranberry juice might help prevent symptomatic urinary tract infections (UTIs), but this finding was refuted in 2012 with a conclusion that "14 further studies suggest that cranberry juice is less