Anne of France (or Anne de Beaujeu; 3 April 146114 November 1522) was a French princess and regent, the eldest daughter of Louis XI by Charlotte of Savoy. Anne was the sister of Charles VIII, for whom she acted as regent during his minority from 1483 until 1491. During the regency she was one of the most powerful women of late fifteenth-century Europe, and was referred to as "Madame la Grande". Between 1503 and 1521, she also acted as de facto regent of the Duchy of Bourbon during the reign of her daughter Suzanne, Duchess of Bourbon. Early life Anne was born at the Chateau of Genappe in Brabant on 3 April 1461, the eldest surviving daughter of King Louis XI of France and Charlotte of Savoy. Her brother, Charles would later succeed their father as Charles VIII of France. Her younger sister Joan became for a brief period, a queen consort of France as the first wife of Louis XII. Marriage Anne was originally betrothed to Nicholas, Duke of Lorraine, and was created Viscountess of Thouars in 1468 in anticipation of the marriage. However, Nicholas broke the engagement to instead pursue Mary of Burgundy, and then died unexpectedly in 1473, prompting Louis to take back the fiefdom. That same year, on 3 November, Anne married Peter of Bourbon instead, and took up rule of the Beaujolais at the same time, when her husband was ceded the title of 'Lord of Beaujeu' by his brother the Duke of Bourbon. Anne was just twelve years old at the time. Regency in France During the minority of Anne's brother, Charles VIII of France, Peter and Anne held the regency of France. This regency lasted from 1483 until 1491. Anne's regency overcame many difficulties, including unrest amongst the magnates who had suffered under Louis XI's oppression. Together Peter and Anne maintained the royal authority and the unity of the kingdom against the Orléans party, which was in open revolt during the "Mad War", which lasted from 1483 until 1488. Concessions, many of which sacrificed Louis's favourites, were made, and land was restored to many of the hostile nobles, including the future Louis XII of France, then Duke of Orléans. Louis tried to obtain the regency, but the Estates General sided with her. As regent of France, Anne was one of the most powerful women in the late fifteenth century, and she was referred