Nicorette is the brand name of a number of products for nicotine replacement therapy (NRT) that contain nicotine polacrilex. Developed in the late 1970s in Sweden by in the form of a chewing gum, Nicorette was the first nicotine replacement product on the market. The product range encompasses chewing gum, lozenges, patches of two kinds (transparent and non-transparent), oral spray (Nicorette QuickMist), inhalator, sublingual tablets (Nicorette Microtab) and nasal spray. The products are manufactured by McNeil Consumer Healthcare company, a subsidiary of Johnson & Johnson, in Helsingborg, Sweden and are sold globally by Johnson & Johnson, even in the Middle East, except for in the United States where Nicorette is distributed by Haleon. Nicotine replacement products including gum and transdermal patches are on the World Health Organization's List of Essential Medicines. The brand name "Nicorette" comes from "nicotine" and , "right way". Medical uses Nicorette products are indicated for the relief of withdrawal symptoms associated with nicotine withdrawal and to aid in smoking cessation. It is suggested that Nicorette products should be used in "conjunction with a behavioural support programme". Prior to 2005, nicotine products in Britain were only licensed to "assist smokers who were making an immediate and complete quit attempt". Following advice from a working group set up by the Committee on Safety of Medicines (since 2005, the Commission on Human Medicines) the MHRA concluded that NRT products should be used also by those who are unable to stop abruptly. Currently Nicorette products in the UK are indicated to: relieve craving (the urge to smoke), relieve withdrawal symptoms (irritability, impatience; difficulty in concentrating), improve the likelihood of a successful abrupt quit attempt, reduce the amount smoked in those not immediately motivated to quit. The products are intended for adults and children over 12 years of age as well as pregnant and lactating women (it has been concluded that "the use of NRT in pregnancy does not give undue concern and any harm caused by nicotine replacement must be compared with that caused by continued smoking – which is extremely harmful to both the woman and her child".) Nicorette, like all other NRT products, are most beneficial for heavy smokers (more than 15 cigarettes per day). There are not enough studies to show that NRT helps those who smoke fewer than 10 cigarettes per day. Contraindications The typical contraindication (reason to not use) for Nicorette products is hypersensitivity to