The Portuguese Inquisition (Portuguese: Inquisição Portuguesa), officially known as the General Council of the Holy Office of the Inquisition in Portugal, was formally established in Portugal in 1536 at the request of its king, John III. Although Manuel I had asked for the installation of the Inquisition in 1515 to fulfill the commitment of his marriage with Maria of Aragon, it was only after his death that Pope Paul III acquiesced. In the period after the Medieval Inquisition, it was one of three different manifestations of the wider Christian Inquisition, along with the Spanish Inquisition and Roman Inquisition. The Goa Inquisition was an extension of the Portuguese Inquisition in colonial-era Portuguese India. History The major target of the Portuguese Inquisition were those who had converted from Judaism to Catholicism, the Conversos (also known as New Christians or Marranos), who were suspected of secretly practicing Judaism. Many of these were originally Spanish Jews who had left Spain for Portugal, when Spain forced Jews to convert to Christianity or leave. The number of victims is estimated as around 40,000. To a lesser extent people of other ethnicities and faiths, such as African practitioners of diasporic African religions and Vodun smuggled through the Atlantic slave trade from the colonies and territories of the Portuguese Empire, were put on trial and imprisoned with the accusations of heresy and witchcraft by the Portuguese Inquisition. As in Spain, the Inquisition was subject to the authority of the King, although the Portuguese Inquisition in practice exercised a considerable degree of institutional independence from both the Crown and the papacy compared to its Spanish counterpart. It was headed by a Grand Inquisitor, or General Inquisitor, named by the Pope but selected by the king, always from within the royal family. The Grand Inquisitor would later nominate other inquisitors. In Portugal, the first Grand Inquisitor was D. Diogo da Silva, personal confessor of King John III and Bishop of Ceuta. He was followed by Cardinal Henry, brother of John III, who would later become king. There were Courts of the Inquisition in Lisbon, Coimbra, and Évora, and for a short time (1541 until c. 1547) also in Porto, Tomar, and Lamego. It held its first auto-da-fé in Portugal in 1540. Like the Spanish Inquisition, it concentrated its efforts on rooting out those who had converted from other faiths (overwhelmingly Judaism) but did not adhere to the strictures of Catholic