College- Columbia Newberry College- Newberry Morris College- Sumter Orangeburg-Calhoun Technical College- Orangeburg South Carolina State University- Orangeburg University of South Carolina- Columbia University of South Carolina Sumter- Sumter Webster University Media The region is served by four commercial television stations, WLTX CBS 19, WOLO ABC 25, WACH FOX 57, and WIS 10. The state's second largest newspaper, The State, is published here. Major highways Interstate 20 Interstate 77 Interstate 95 Interstate 26 Interstate 126 US 321 US 21 US Route 1 US 76 US 176 US 178 US 378 US 15 US 301 US 601 US 521 SC 277 SC 12 SC 34 SC 261 References Regions of South Carolina