Manilkara zapota, commonly known as sapodilla (), sapote, chicozapote, chico, chicle, naseberry, or nispero, among other names, is a long-lived, evergreen tree native to southern Mexico, Central America and the Caribbean. An example natural occurrence is in coastal Yucatán in the Petenes mangroves ecoregion, where it is a subdominant plant species. It was introduced to the Philippines during Spanish colonization. It is grown in large quantities in Mexico and in tropical Asia including India, Pakistan, Thailand, Malaysia, Cambodia, Indonesia, Vietnam, Bangladesh. The specific epithet zapota is from the Spanish , which ultimately derives from the Nahuatl word tzapotl. Description Sapodilla can grow to more than tall with a trunk diameter of up to . The average height of cultivated specimens, however, is usually between with a trunk diameter not exceeding . It is wind-resistant and the bark is rich in a white, gummy latex called chicle. The ornamental leaves are medium green and glossy. They are alternate, elliptic to ovate, long, with an entire margin. The white flowers are inconspicuous and bell-like, with a six-lobed corolla. An unripe fruit has a firm outer skin and when picked, releases white chicle from its stem. A fully ripened fruit has saggy skin and does not release chicle when picked. The fruit is a large berry, in diameter. Inside, its flesh ranges from a pale yellow to an earthy brown color with a grainy texture akin to that of a well-ripened pear. Each fruit contains one to six seeds. The seeds are hard, glossy, and black, resembling beans, with a hook at one end that can catch in the throat if swallowed. The fruit has an exceptionally sweet, malty flavor. The unripe fruit is hard to the touch and contains high amounts of saponin, which has astringent properties similar to tannin, drying out the mouth. The trees can survive only in warm, typically tropical environments, dying easily if the temperature drops below freezing. From germination, the sapodilla tree will usually take anywhere from five to eight years to bear fruit. The sapodilla trees yield fruit twice a year, though flowering may continue year round. Other names Most of the common names of Manilkara zapota like "sapodilla" and "chicozapote" come from Spanish meaning "little sapote". Other common names in English for Manilkara zapota include bully tree, sawo, and marmalade plum. Biological studies Compounds extracted from the leaves showed anti-diabetic, antioxidant and hypocholesterolemic (cholesterol-lowering) effects