in the Open Era, after Djokovic, to complete the double Career Grand Slam. At the Mexican Open, Nadal won the title without dropping a set, which included a win over Medvedev, who that week had clinched the world No. 1 ranking. He also extended his winning streak to 15 matches, his best start to a season in his career. Nadal next entered the 2022 Indian Wells Masters as the fourth seed. After seeing off a final set tie-break from Sebastian Korda in the second round, Nadal beat Dan Evans, Reilly Opelka, Nick Kyrgios, and Carlos Alcaraz to reach his fourth final of the season and extend his winning streak to 20 matches. Nadal was beaten by Taylor Fritz in straight sets in the final, ending his winning streak. On 22 March, it was reported that Nadal will be unable to play for between four and six weeks, due to a rib stress fracture that occurred during Indian Wells. Nadal returned at the Madrid Open, where he defeated Miomir Kecmanovic, David Goffin in the second and third rounds respectively. He then lost to Carlos Alcaraz in a rematch of their Indian Wells semifinal. Nadal then entered Rome, where he was the defending champion. He defeated John Isner in straight sets, but then lost to Denis Shapovalov in three sets despite leading by a set and a break. At the French Open, Nadal recorded his 106th win defeating Jordan Thompson in the first round. With a 106–3 record at the French Open, he became the player with the most wins at a single major. He recorded his 300th career major win by defeating Corentin Moutet in the second round. He defeated Botic van de Zandschulp in the third round and faced Felix Auger Aliassime (coached by Nadal's uncle Toni) in the fourth round, winning the encounter after being taken to five sets for only the third time in his career at the French Open. Nadal met Djokovic for a record-extending 59th time in the quarterfinals - the first singles match in tennis history to feature two players each holding at least 20 Grand Slam titles and 1000 career match wins. Nadal emerged victorious in four sets to advance to his 15th French Open semifinal. He faced Alexander Zverev in a grueling battle lasting over three hours with only two sets played, and ended with Zverev's retirement due to an ankle injury. As