Ludlow was twenty-one years old. The book was a success, going through a few printings in short order, and Ludlow, although he published both the book and his earlier article The Apocalypse of Hasheesh anonymously, was able to take advantage of the book's notoriety. For a time he studied law under William Curtis Noyes (himself a lawyer who had begun his legal studies at the age of fourteen in the offices of Ludlow's uncle Samuel). Ludlow passed the bar exam in New York in 1859, but never practiced law, instead deciding to pursue a literary career. The late 1850s marked a changing of the guard in New York City literature. Old guard literary magazines like The Knickerbocker and Putnam’s Monthly were fading away, and upstarts like the Atlantic Monthly, The Saturday Press, and Vanity Fair were starting up. Ludlow took on a position as an associate editor at Vanity Fair, a magazine which at the time resembled Punch in tone. It was probably through the Vanity Fair staff that Ludlow was introduced to the New York City bohemian and literary culture, centered around Pfaff's beer cellar on Broadway and Saturday night gatherings at Richard Henry Stoddard’s home. This scene attracted the likes of Walt Whitman, Fitz James O’Brien, Bayard Taylor, Thomas Bailey Aldrich, Edmund Clarence Stedman, and Artemus Ward. New York City’s vibrant literary scene and cosmopolitan attitudes were a boon to Ludlow. “It is a bath of other souls,” he wrote. “It will not let a man harden inside his own epidermis. He must affect and be affected by multitudinous varieties of temperament, race, character.” New York was tolerant of iconoclasts and of people with just the sort of notoriety Ludlow had cultivated. “No amount of eccentricity surprises a New-Yorker, or makes him uncourteous. It is difficult to attract even a crowd of boys on Broadway by an odd figure, face, manner, or costume. This has the result of making New York an asylum for all who love their neighbor as themselves, but would a little rather not have him looking through the key-hole.” The late 1850s and early 1860s found Ludlow in just about every literary quarter of New York. He wrote for, among many others, the Harper's publications (Weekly, Monthly and Bazar), the New York World, Commercial Advertiser, Evening Post, and Home Journal, and for Appleton’s, Vanity Fair, Knickerbocker, Northern Lights, The Saturday Press, and the Atlantic