John McQueen (D), until December 21, 1860 . William P. Miles (D), until December 21, 1860 . Laurence M. Keitt (D), until December 1860 . Milledge L. Bonham (D), until December 21, 1860 . John D. Ashmore (D), until December 21, 1860 . William W. Boyce (D), until December 21, 1860 Tennessee . Thomas A. R. Nelson (O) . Horace Maynard (O) . Reese B. Brabson (O) . William B. Stokes (O) . Robert H. Hatton (O) . James H. Thomas (D) . John V. Wright (D) . James M. Quarles (O) . Emerson Etheridge (O) . William T. Avery (D) Texas . John H. Reagan (D) . Andrew J. Hamilton (ID) Vermont . Eliakim P. Walton (R) . Justin S. Morrill (R) . Homer E. Royce (R) Virginia . Muscoe R. H. Garnett (D) . John S. Millson (D) . Daniel C. De Jarnette (ID) . William Goode (D), until July 3, 1859 Roger A. Pryor (D), from December 7, 1859 . Thomas S. Bocock (D) . Shelton Leake (ID) . William Smith (D) . Alexander Boteler (O) . John T. Harris (ID) . Sherrard Clemens (D) . Albert G. Jenkins (D) . Henry A. Edmundson (D) . Elbert S. Martin (ID) Wisconsin . John F. Potter (R) . Cadwallader C. Washburn (R) . Charles H. Larrabee (D) Non-voting members . Marcus J. Parrott (R), until January 29, 1861 . Experience Estabrook, until May 18, 1860 Samuel G. Daily (R), from May 18, 1860 . Miguel A. Otero (D) . William H. Hooper (D) . Isaac Stevens (D) Changes in membership The count below reflects changes from the beginning of the first session of this Congress. Senate Replacements: 4 Democrats (D): no net change Republicans (R): no net change Deaths: 1 Resignations: 1 Interim appointments: 1 Withdrawals: 13 Total seats with changes: 16 |- | Oregon(2) | Vacant | Successor elected late due to legislature's failure to elect. | | Edward D. Baker (R) | October 2, 1860 |- | California(1) | | David C. Broderick (D) | Died September 16, 1859, after taking part in a duel he participated in, which he was unlucky.Interim successor was appointed to continue the term. | | Henry P. Haun (D) | November 3, 1859 |- | Texas(1) | | Matthias Ward (D) | Interim appointee lost nomination to finish the termSuccessor elected December 5, 1859. | | Louis Wigfall (D) |