Sir Almroth Edward Wright (10 August 1861 – 30 April 1947) was a British bacteriologist and immunologist. He is notable for developing a system of anti-typhoid fever inoculation, recognizing early on that antibiotics would create resistant bacteria, and being a strong advocate for preventive medicine. Biography Wright was born at Middleton Tyas, near Richmond, North Yorkshire into a family of mixed Anglo-Irish and Swedish descent. He was the son of Reverend Charles Henry Hamilton Wright, deacon of Middleton Tyas, who later served in Belfast, Dublin, and Liverpool and managed the Protestant Reformation Society. His mother, Ebba Almroth, was the daughter of , Governor of the Swedish Royal Mint in Stockholm. His younger brother Charles Theodore Hagberg Wright became the librarian of the London Library. In 1882, he graduated from Trinity College Dublin with first-class honours in modern literature and won a gold medal in modern languages and literature. Simultaneously he took medicine courses and in 1883 graduated in medicine. In the late 19th century, Wright worked with the armed forces of Britain to develop vaccines and promote immunisation. He married Jane Georgina Wilson (1861-1926) in 1889 and had three children. The first, Edward Robert Mackay Wright (1890-1913), was born in Glebe, Sydney. Second son Leonard Almoth Wilson Wright (1891-1972) was born in Dublin, as was daughter Doris Helena MacNaughton Wright (later Romanes, after whom the Helena Romanes School was named) (1894-1990). In 1902, Wright started a research department at St Mary's Hospital Medical School in London. He developed a system of anti-typhoid fever inoculation and brought the humoral and cellular theories of immunity together by showing the cooperation of a substance (that he named opsonin) contained in the serum with the phagocytes against pathogens. Citing the example of the Second Boer War, during which many soldiers died from easily preventable diseases, Wright convinced the armed forces that 10 million vaccine doses for the troops in northern France should be produced during World War I. During WWI Wright established a research laboratory attached to the British Expeditionary Force's hospital designated Number 13, General Hospital in Boulogne-sur-Mer. In 1919 Wright returned to St Mary's and remained there until his retirement in 1946. Among the many bacteriologists who followed in Wright's footsteps at St Mary's was Sir Alexander Fleming, who in turn later discovered lysozyme and penicillin. Wright was elected a Fellow of the Royal Society in May 1906. Leonard Colebrook became his