R. radiobacter are colonizing the host plant and participate to steer the coordination of microbe-plant interaction. AHLs and Nitrogen Cycle Microbes are a key player in charge of the fate of nitrogen in soil and water. AHL-mediated quorum sensing has an important role in Nitrogen cycle. All nitrifying bacteria and some denitrifying bacteria use AHL as their signal molecules. AHLs influence the efficiency of and regulate the functions involved in nitrification and denitrification. Some bacterial species of ammonia-oxidizing bacteria, like Nitrosomonas europaea, Nitrosospira multiformis, Nitrosospira briensis, use C6- to C14- AHLs. Nitrite-oxidizing bacteria (NOB), such as Nitrobacter winogradskyi, Nitrobacter vulgaris, and Nitrospira moscoviensis, also use C8- or C10- AHLs. Candidatus Jettenia caeni with anaerobic ammonium oxidation (annamox) mode uses C6- and C8- AHLs. Moreover, Pseudomonas aeruginosa and Paracoccus denitrificans as denitrifying bacteria also use C4-HSL and C16-AHL, respectively. In some of the nitrifying and denitrifying bacteria like Nitrobacter hamburgensis AHLs were not found although putative AHL synthetase and receptor proteins were. See also Lactonase Further reading (discovery of homoserine lactone) Zhang Q, Li S, Hachicha M, Boukraa M, Soulère L, Efrit ML, Queneau Y. Heterocyclic Chemistry Applied to the Design of N-Acyl Homoserine Lactone Analogues as Bacterial Quorum Sensing Signals Mimics. Molecules. 2021; 26(17):5135. https://doi.org/10.3390/molecules26175135 Notes Cell signaling Carboxamides Tetrahydrofurans