Santee may refer to: People Santee Dakota, a subgroup of the Dakota people, of the U.S. Great Plains Santee (South Carolina), a Native American people of South Carolina Places Lake Santee, Indiana, a reservoir and census-designated place Santee, California Santee (Corbin, Virginia), a historic plantation home Santee Indian Reservation in Nebraska Santee, Nebraska Santee, South Carolina Santee River in South Carolina Other uses Santee (surname) Santee Education Complex, Los Angeles, California Santee (film), a 1973 western starring Glenn Ford Santee (plumbing), a tee joint in a sanitation line USS Santee, multiple ships of the United States Navy