leads to inadequate H2O2 production, while myeloperoxidase deficiency is characterized by a lack of myeloperoxidase to interact with present H2O2. Testing with NADPH oxidase-specific assays can lead to positive results for chronic granulomatous disease and negative results for myeloperoxidase deficiency. Treatment Most individuals with myeloperoxidase deficiency do not need regular treatment, as they experience only mild symptoms, if any at all. Continued antibiotic use is not recommended in myeloperoxidase-deficient patients who don’t experience recurrent infections. Acquired myeloperoxidase deficiency typically goes away when the underlying condition is treated. In particular, when myeloperoxidase deficiency is caused by severe iron deficiency, treatment with iron returns myeloperoxidase function to normal. References External links Enzyme defects Congenital defects of phagocyte number, function, or both Noninfectious immunodeficiency-related cutaneous conditions