The Battle of San Domingo was a naval battle of the Napoleonic Wars fought on 6 February 1806 between squadrons of French and British ships of the line off the southern coast of the French-occupied Spanish colonial Captaincy General of Santo Domingo (San Domingo in contemporary British English) in the Caribbean. All five of the French ships of the line commanded by Vice-Admiral Corentin-Urbain Leissègues were captured or destroyed. The Royal Navy led by Vice-Admiral Sir John Thomas Duckworth lost no ships and suffered fewer than a hundred killed while the French lost approximately 1,500 men. Only a small number of the French squadron were able to escape. The battle of San Domingo was the last fleet engagement of the war between French and British capital ships in open water. Background In late 1805, First Lord of the Admiralty Lord Barham withdrew the Royal Navy blockade of the French Atlantic ports following the Trafalgar Campaign, in which the French Navy had lost 14 ships of the line. Barham believed that the French, having suffered such heavy losses, would be unable and unwilling to launch a major offensive in the Atlantic until after the winter. However, he had miscalculated the strength of the fleet at Brest, the principal French Atlantic seaport. The Brest fleet had not been engaged in the 1805 campaign and was therefore intact. Taking advantage of the withdrawal of the British blockade, Emperor Napoleon ordered two squadrons to put to sea with orders to raid the British trade routes that crossed the Atlantic. These forces were to inflict as much economic damage to Britain as possible without engaging an equivalent British naval squadron and risking defeat and capture. The cruise was expected to last as long as 14 months, sustained by captured food supplies from British merchant ships. Sailing unopposed on 13 December 1805, the squadrons separated two days later in pursuit of British merchant convoys, one squadron steering for the South Atlantic under Contre-Admiral Jean-Baptiste Willaumez and the other, under Vice-Admiral Corentin-Urbain Leissègues, sailing for the Caribbean. The Admiralty in London did not discover that the French had sailed until 24 December, and the two squadrons they prepared in pursuit, under Rear-Admiral Sir Richard Strachan and Rear-Admiral Sir John Borlase Warren, did not sail until January 1806, by which time the French had disappeared into the Atlantic. There was however one British squadron that had maintained contact