adults aged 0–21 throughout Cleveland and the wider northern Ohio region. Cleveland Clinic Children's Hospital also sometimes treats adults that require pediatric care. The hospital is a few blocks away from the Ronald McDonald House of Cleveland. U.S. locations In May 2010, Cleveland Clinic's Lou Ruvo Center for Brain Health opened in a unique structure designed by architect Frank Gehry in Las Vegas, Nevada. In 2018, the Indian River Medical Center in Vero Beach, Florida, and Martin Health, consisting of a hospital in Port St. Lucie and two hospitals in Stuart, Florida, joined the Cleveland Clinic system. International locations In 2006, the Cleveland Clinic opened Cleveland Clinic Canada, a 26,000-square-foot outpatient clinic in downtown Toronto, offering both Ontario Health Insurance Plan (OHIP) and non-OHIP services. In 2017, Cleveland Clinic Canada acquired the Sports Medicine Specialists located in midtown Toronto. An overseas location, Cleveland Clinic Abu Dhabi, opened in 2015. The organization began work renovating an historic building at 33 Grosvenor Place in central London, England, in 2018. Demolition of the interior of the six-story, 198,000-square-foot building has begun, with an estimated opening date in early 2022. Finances In 2011 Cleveland Clinic was second on the Becker's Hospital Review list of top-grossing hospitals in the United States, with total patient revenue of $9.14 billion. The hospital posted $243 million operating income on $8 billion revenue in 2016. Operating income fell about 50% from 2015, which it said was due to shrinking reimbursements and rising drug costs. In 2017 its operating income was $330M on $8.4B in revenue. In 2015, the Clinic's endowment stood at more than $12 billion. During the coronavirus pandemic, the Cleveland Clinic received a $199 million grant from the United States Department of Health and Human Services under the CARES Act, funding that was intended to prevent health care providers from going under. In 2019, the Cleveland Clinic reported having $7 billion in cash reserves, with investment profits of $1.2 billion. In addition, Cleveland Clinic plays a significant role in the regional economy of Cleveland and the statewide economy. As of 2019, it is Ohio's largest employer, and generates $17.8 billion for the state. See also List of hospitals in the United States Medical centers in the United States List of hospitals by capacity List of hospitals by staff References Further reading Hospital buildings completed in 1921 Hospitals in Cleveland Buildings and structures in Cleveland 1921 establishments in