Medical Center ranks among top 15 centers in the United States with approximately $75 million in annual extramural research funding and a further $20 million in various clinical trials. University Hospitals Cleveland Medical Center also includes MacDonald Women's Hospital, Ohio's only hospital for women; and Seidman Cancer Center (formerly known as Ireland Cancer Center). Vision 2010 Vision 2010 was the largest construction and upgrade project in the history of University Hospitals. New construction included a new 200-bed cancer hospital (UH Seidman cancer center), upgraded emergency room facilities at CMC, a new neonatal intensive care unit (NICU) at Rainbow Babies & Children's Hospital, and new construction at other hospital sites. The capital expenditure for this project, according to hospital press releases, was to be approximately US$1 billion. Construction was originally due to be completed by the year 2010, but was not scheduled completed until 2011. Harrington Project The Harrington Project for Discovery & Development, launched in 2012, is a $300 million initiative at the University Hospitals whose purpose is to speed the delivery of new drugs and enhance the medical reputations of Cleveland and the Hospitals. It was established through a $50 million gift from the Harrington family and an additional $100 million in support from University Hospitals. The project has three components, the Harrington Discovery Institute (HDI), the Innovation Support Center (ISC), and Biomotiv. In June 2014, the Harrington Discovery Institute received a $25 million grant from the State of Ohio through the Third Frontier economic development program to further its mission. Notable alumni and faculty George Washington Crile (1910-1924 Chair of Surgery) - Performed first blood transfusion. Established Lakeside Hospital of University Hospitals Case Medical Center, and later co-founded Cleveland Clinic Claude Beck (Surgery residency alum; 1924 -1971 Professor of Cardiovascular Surgery - first such position in US) Performed first surgical treatment of coronary artery disease (1935). Performed first defibrillation using machine he built with James Rand (1947) Developed concept of Beck's Triad Started the first CPR teaching course for medical professionals (1950). Peter C. Agre (1978 Internal Medicine alumnus) - co-recipient 2003 Nobel Prize in Chemistry for discoveries that have clarified how salts and water are transported out of and into the cells of the body, leading to a better understanding of many diseases of the kidneys, heart, muscles and nervous system. Alfredo Palacio (Internal Medicine alumnus) - President of Ecuador (2005–2007) Peter Pronovost - intensive care physician