when humans reject the calling of the Holy Spirit, it is not a result of the Word being less efficacious. Instead, contempt for the means of grace is the result of "the perverse will of man, which rejects or perverts the means and instrument of the Holy Ghost, which God offers him through the call, and resists the Holy Ghost, who wishes to be efficacious, and works through the Word..." Lutherans are certain that the work of the Holy Spirit does not occur merely alongside the means of grace to regenerate, but instead is an integral part of them, always working through them wherever they are found. Lutherans teach that the Holy Spirit limits himself to working only through the means of grace and nowhere else, so that those who reject the means of grace are simultaneously resisting and rejecting the Holy Spirit and the grace he brings. Biblical passages related to the doctrine The statement of St. Paul is said to confirm that those whom God effectually calls necessarily come to full salvation: "(T)hose whom (God) predestined He also called, and those whom He called He also justified, and those whom He justified He also glorified" (Romans 8:28,30). Of course, this confirmation depends upon the belief that when God elected certain individuals for salvation, He either did not know or did not consider who would respond and obey, though the Apostle Peter refers to the "Elect according to the foreknowledge of God the Father, through sanctification of the Spirit, unto obedience and sprinkling of the blood of Jesus Christ". Calvinists also rely upon several verses from the sixth chapter of the Gospel of John, which contains a record of Jesus' teaching on humanity's abilities and God's activities in salvation, as the central proof text for the Calvinist doctrine: John 6:37,39: "All that the Father gives me will come to me.... And this is the will of Him who sent me, that I should lose nothing of all that He has given me, but raise it up on the last day."[ESV] John 6:44–45: "No one can come to me unless the Father who sent me draws him.... Everyone who has heard and learned from the Father comes to me."[ESV] John 6:65: "(N)o one can come to me unless it is granted him by the Father."[ESV] Proponents of Arminianism argue that the word "draw" (Greek: , helkô) as used in John