U.S. Route 521 (US 521) is a north–south United States Highway that traverses , from Georgetown, South Carolina, to Charlotte, North Carolina. Though numbered as an auxiliary route of US 21, it does not actually intersect its parent or any of its sibling routes, though it is in the same general part of the country as other routes from its family. Historically, it once connected to US 21 in Pineville, North Carolina, but various changes have left it terminating a few miles short of the current US 21. Route description South Carolina Starting at the city of Georgetown, US 521 runs through the town Andrews to Greeleyville. From here to the city of Manning it is known as the Greeleyville Highway. There is a brief section right before Manning where it runs concurrent with SC 261. In Manning SC 261 branches off and US 521 merges with US 301 for a short distance. It crosses over Interstate 95 (I-95) and heads to the city of Sumter. In Sumter, it runs together with US Business 378. Leaving Sumter, US 521 is known as Camden Highway. It passes under I-20 and proceeds to Camden. It then goes on to the town of Kershaw, running concurrent with US 601. The final city it goes through before going into North Carolina is Lancaster. North Carolina US 521 traverses from the South Carolina state line to I-485. The entire route is a four- to six-lane divided highway, split in naming between Lancaster Highway and Johnston Road. History Established in 1932, it was overlapped entirely with SC 26, from Georgetown to the North Carolina state line, where it continued with NC 26 into Pineville, where it ended at U.S. Route 21/NC 261 (now NC 51). In 1933, SC 26 was decommissioned; followed in 1934 with the decommissioning of NC 26. In 1949, US 521 was rerouted in Williamsburg County to run directly from Andrews, through Salters and Greeleyville, to Manning; which replaced SC 171 and part of SC 261, the old alignment became part of SC 377 and SC 261. Between 1962 and 1964, US 521 was rerouted at the Sumter-Kershaw county line to Camden; the old alignment became an extension of SC 261. In 1969, US 521 was extended north, via South Boulevard, and Wilkinson Blvd, then in 1981, by way of Woodlawn Road, and Billy Graham Parkway, to I-85 in Charlotte. Between 1986 and