U.S. Route 341 (US 341) is a U.S. highway entirely in the U.S. state of Georgia. It travels diagonally across southern Georgia (but is signed as north–south) from Brunswick at US 17/SR 25 to Barnesville at US 41/SR 7/SR 18. It is a spur route of US 41 and has two intersections with it: in Perry and at its northern terminus in Barnesville. Route description The following portions of US 341 are part of the National Highway System, a system of routes determined to be the most important for the nation's economy, mobility, and defense: From its southern terminus in Brunswick to the US 41 intersection in Perry From just south-southeast of Fort Valley to just north-northwest of Fort Valley. Brunswick to Jesup US 341 begins at an intersection with US 17 and SR 25 (Glynn Avenue) in the southeast corner of the city of Brunswick, a short distance north of the Sidney Lanier Bridge. US 341 and its state route companion, SR 27, head west along 4th Street, a four-lane undivided street. The highway turns north onto Newcastle Street and passes along the edge of the Port of Brunswick. Newcastle Street becomes two lanes at 1st Avenue; US 341/SR 27 turns west onto Prince Street then north onto Bay Street, which becomes a four-lane divided highway immediately to the south of the intersection. The highway parallels Norfolk Southern Railway's Brunswick District north between downtown Brunswick to the east and an industrial area along the East River. At the north end of downtown, US 341 has an oblique intersection with US 25 (Newcastle Street), whose companion route is SR 25 Connector (SR 25 Conn.) and which serves as the main street of downtown Brunswick. US 25/US 341/SR 27 continues north along Newcastle Street as a four-lane highway with center turn lane out of the city of Brunswick. The highway has a partial interchange with Norwich Street and its name changes to Norwich Street Extended. The highways cross over the paralleling rail line and have a partial interchange with Ross Road and another road that parallels the railroad. In the unincorporated community of Dock Junction, the highways intersect SR 303, which heads east as Community Road and west as Blythe Island Highway. Immediately to the south of the intersection is an acute intersection with SR 303 Conn., which serves as a cutoff between US 25/US 341/SR 27 and SR 303. The