SC 341 in Lake City. In 1939, SC 54, along with US 52 and SC 341, was extended farther into Lake City. Then, SC 54 was extended to SC 51 in Salem. Between 1943 and 1947, its path just west of the Lynches River was straightened out. In late 1951, it was decommissioned; most of its path was redesignated as part of US 378. Future Major intersections Special routes Sumter business loop U.S. Route 378 Business (US 378 Bus.) was a business route of US 378 that existed in Sumter. It used Broad Street, Liberty Street, and Myrtle Beach Boulevard. It was established in 1958 as a renumbering of mainline US 378 through downtown Sumter. Lake City business loop U.S. Route 378 Business (US 378 Bus.) is a business route of US 378 through Lake City. The highway travels from US 378 and South Carolina Highway 341 (SC 341) west of the city to US 378 east of the city. US 378 Bus. begins heading east from US 378 (Turbeville Highway) concurrent with SC 341 along two-lane Main Street. The two highways enter the city just east of Lake City Memorial Park. In the center of the city, US 378 Bus. and SC 341 have an intersection with US 52 (Ron McNair Boulevard). One block after their grade crossing of CSX's Charleston Subdivision, the highways diverge. The main highway continues east on Main Street while the business route turns north onto Church Street. US 378 Bus. leaves the city limits at its crossing of Lake Swamp and reaches its eastern terminus at US 378 (Myrtle Beach Highway). Conway truck route U.S. Route 378 Truck (US 378 Truck) is a truck route of US 378 that partially exists in Conway and Red Hill. It directs truck traffic onto US 501, South Carolina Highway 544 Connector (Red Hill 1) (SC 544 Conn.), US 501 Business (US 501 Bus.), SC 90, Old Reaves Ferry Road, and SC 905. Its entire length is concurrent with US 701 Truck. It is loosely signed, frequently in Conway and Red Hill, and infrequently outside the city limits of both locales. See also References External links The Highways of South Carolina: US 378 Endpoints of U.S. Highway 378 78-3 78-3 78-3 3 Transportation in Wilkes County, Georgia Transportation in Lincoln County, Georgia Transportation in McCormick County, South Carolina Transportation in Edgefield County, South Carolina Transportation in Saluda County,