Apalachicola may refer to: Apalachicola people, a group of Native Americans who lived along the Apalachicola River in present-day Florida Places Apalachicola, Florida Apalachicola River Apalachicola Bay Apalachicola National Forest Apalachicola Regional Airport Port of Apalachicola Railroad Apalachicola and Alabama Railroad Apalachicola Northern Railroad Ships , a tugboat in the United States Navy.