$146 billion in 2014, the 21st-highest in the country, up from $144 billion in 2013, $138.4 billion in 2012, and $133.1 billion in 2011. The St. Louis metropolitan area had a per-capita GDP of $48,738 in 2014, up 1.6% from the previous year. In 2007, manufacturing in the city conducted nearly $11 billion in business, followed by the health care and social service industry with $3.5 billion; professional or technical services with $3.1 billion; and the retail trade with $2.5 billion. The health care sector was the area's biggest employer with 34,000 workers, followed by administrative and support jobs, 24,000; manufacturing, 21,000, and food service, 20,000. Major companies and institutions As of 2022, the St. Louis Metropolitan Area is home to seven Fortune 500 companies. They include Centene, Emerson Electric, Reinsurance Group of America, Edward Jones, Olin, Graybar Electric, and Ameren. Other notable corporations headquartered in the region include Arch Coal, Bunge Limited, Wells Fargo Advisors (formerly A.G. Edwards), Energizer Holdings, Patriot Coal, Post Foods, United Van Lines, and Mayflower Transit, Post Holdings, Olin, Enterprise Holdings (a parent company of several car rental companies). Notable corporations with operations in St. Louis include Cassidy Turley, Kerry Group, Mastercard, TD Ameritrade, BMO Harris Bank, and World Wide Technology. Health care and biotechnology institutions with operations in St. Louis include Pfizer, the Donald Danforth Plant Science Center, the Solae Company, Sigma-Aldrich, and Multidata Systems International. General Motors manufactures automobiles in Wentzville, while an earlier plant, known as the St. Louis Truck Assembly, built GMC automobiles from 1920 until 1987. Chrysler closed its St. Louis Assembly production facility in nearby Fenton, Missouri and Ford closed the St. Louis Assembly Plant in Hazelwood. Several once-independent pillars of the local economy have been purchased by other corporations. Among them are Anheuser-Busch, purchased by Belgium-based InBev; Missouri Pacific Railroad, which was headquartered in St. Louis, merged with the Omaha, Nebraska-based Union Pacific Railroad in 1982; McDonnell Douglas, whose operations are now part of Boeing Defense, Space & Security; Trans World Airlines, which was headquartered in the city for its last decade of existence, prior to being acquired by American Airlines; Mallinckrodt, purchased by Tyco International; and Ralston Purina, now a wholly owned subsidiary of Nestlé. The May Department Stores Company (which owned Famous-Barr and Marshall Field's stores) was purchased by Federated Department Stores, which has its regional headquarters in the area. The Federal Reserve Bank of St.