book Il Cortigiano, encouraged all his daughters (Sofonisba, Elena, Lucia, Europa, Minerva and Anna Maria) to cultivate and perfect their talents. Four of the sisters (Elena, Lucia, Europa and Anna Maria) became painters, but Sofonisba was by far the most accomplished and renowned and taught her younger siblings. Elena Anguissola (c. 1532 – 1584) abandoned painting to become a nun. Both Anna Maria and Europa gave up art upon marrying, while Lucia Anguissola (1536 or 1538 – 1565–1568), the best painter of Sophonisba's sisters, died young. The remaining sister, Minerva, became a writer and Latin scholar. Asdrubale, Sophonisba's brother, studied music and Latin, but not painting. Her aristocratic father made sure that Anguissola and her sisters received a well-rounded education that included the fine arts. Anguissola was fourteen when her father sent her and her sister Elena to study with Bernardino Campi, a respected portrait and religious painter of the Lombard school. When Campi moved to another city, Anguissola continued her studies with painter Bernardino Gatti (known as Il Sojaro), a pupil of Correggio's. Anguissola's apprenticeship with local painters set a precedent for women to be accepted as students of art. Dates are uncertain, but Anguissola probably continued her studies under Gatti for about three years (1551–1553). One of Anguissola's most important early works was Bernardino Campi Painting Sofonisba Anguissola (c. 1550). The unusual double portrait depicts Anguissola's art teacher in the act of painting a portrait of her. In 1554, at age twenty-two, Anguissola traveled to Rome, where she spent her time sketching various scenes and people. While in Rome, she was introduced to Michelangelo by another painter who was familiar with her work. Anguissola initially showed Michelangelo a drawing of a laughing girl, but the painter challenged her to draw a weeping boy, a subject which he felt would be more challenging. Anguissola drew Boy Bitten by a Crayfish and sent it back to Michelangelo, who immediately recognized her talent. Michelangelo subsequently gave Anguissola sketches from his notebooks to draw in her own style and offered advice on the results. For at least two years, Anguissola continued this informal study, receiving substantial guidance from Michelangelo. Experiences as a female artist Anguissola's education and training had different implications from those of men, since men and women worked in separate spheres. Her training was not to help her into a profession where she would compete for commissions with male artists,