to conduct scientific research, deploy commercial, military, and scientific payloads, and was involved in the construction and operation of Mir and the ISS. During its tenure, the Space Shuttle served as the only U.S. vehicle to launch astronauts, of which there was no replacement until the launch of Crew Dragon Demo-2 on May 30, 2020. Budget The overall NASA budget of the Space Shuttle program has been estimated to be $221 billion (in 2012 dollars). The developers of the Space Shuttle advocated for reusability as a cost-saving measure, which resulted in higher development costs for presumed lower costs-per-launch. During the design of the Space Shuttle, the Phase B proposals were not as cheap as the initial Phase A estimates indicated; Space Shuttle program manager Robert Thompson acknowledged that reducing cost-per-pound was not the primary objective of the further design phases, as other technical requirements could not be met with the reduced costs. Development estimates made in 1972 projected a per-pound cost of payload as low as $1,109 (in 2012) per pound, but the actual payload costs, not to include the costs for the research and development of the Space Shuttle, were $37,207 (in 2012) per pound. Per-launch costs varied throughout the program and were dependent on the rate of flights as well as research, development, and investigation proceedings throughout the Space Shuttle program. In 1982, NASA published an estimate of $260 million (in 2012) per flight, which was based on the prediction of 24 flights per year for a decade. The per-launch cost from 1995 to 2002, when the orbiters and ISS were not being constructed and there was no recovery work following a loss of crew, was $806 million. NASA published a study in 1999 that concluded that costs were $576 million (in 2012) if there were seven launches per year. In 2009, NASA determined that the cost of adding a single launch per year was $252 million (in 2012), which indicated that much of the Space Shuttle program costs are for year-round personnel and operations that continued regardless of the launch rate. Accounting for the entire Space Shuttle program budget, the per-launch cost was $1.642 billion (in 2012). Disasters On January 28, 1986, STS-51-L disintegrated 73 seconds after launch, due to the failure of the right SRB, killing all seven astronauts on board Challenger. The disaster was caused by the low-temperature impairment of an O-ring, a mission-critical seal