as bootstrapping. Self-modifying code is possible to write (programs which operate on themselves), both with assembler and with functional languages such as Lisp, but is generally discouraged in real-world programming. Computing hardware makes fundamental use of self-reference in flip-flops, the basic units of digital memory, which convert potentially paradoxical logical self-relations into memory by expanding their terms over time. Thinking in terms of self-reference is a pervasive part of programmer culture, with many programs and acronyms named self-referentially as a form of humor, such as GNU ('GNU's not Unix') and PINE ('Pine is not Elm'). The GNU Hurd is named for a pair of mutually self-referential acronyms. Tupper's self-referential formula is a mathematical curiosity which plots an image of its own formula. In biology The biology of self-replication is self-referential, as embodied by DNA and RNA replication mechanisms. Models of self-replication are found in Conway's Game of Life and have inspired engineering systems such as the self-replicating 3D printer RepRap. In art Self-reference occurs in literature and film when an author refers to his or her own work in the context of the work itself. Examples include Miguel de Cervantes' Don Quixote, Shakespeare's A Midsummer Night's Dream, The Tempest and Twelfth Night, Denis Diderot's Jacques le fataliste et son maître, Italo Calvino's If on a winter's night a traveler, many stories by Nikolai Gogol, Lost in the Funhouse by John Barth, Luigi Pirandello's Six Characters in Search of an Author, Federico Fellini's 8½ and Bryan Forbes's The L-Shaped Room. Speculative fiction writer Samuel R. Delany makes use of this in his novels Nova and Dhalgren. In the former, Katin (a space-faring novelist) is wary of a long-standing curse wherein a novelist dies before completing any given work. Nova ends mid-sentence, thus lending credence to the curse and the realization that the novelist is the author of the story; likewise, throughout Dhalgren, Delany has a protagonist simply named The Kid (or Kidd, in some sections), whose life and work are mirror images of themselves and of the novel itself. In the sci-fi spoof film Spaceballs, Director Mel Brooks includes a scene wherein the evil characters are viewing a VHS copy of their own story, which shows them watching themselves "watching themselves", ad infinitum. Perhaps the earliest example is in Homer's Iliad, where Helen of Troy laments: "for generations still unborn/we will live in song" (appearing in the song itself). Self-reference in