regarding the remedial surgery in horror, Freud could bring himself only to intimate delicately in his correspondence with Fliess the nature of his disastrous role, and in subsequent letters maintained a tactful silence on the matter or else returned to the face-saving topic of Eckstein's hysteria. Freud ultimately, in light of Eckstein's history of adolescent self-cutting and irregular nasal (and menstrual) bleeding, concluded that Fliess was "completely without blame", as Eckstein's post-operative haemorrhages were hysterical "wish-bleedings" linked to "an old wish to be loved in her illness" and triggered as a means of "rearousing [Freud's] affection". Eckstein nonetheless continued her analysis with Freud. She was restored to full mobility and went on to practice psychoanalysis herself. Freud, who had called Fliess "the Kepler of biology", later concluded that a combination of a homoerotic attachment and the residue of his "specifically Jewish mysticism" lay behind his loyalty to his Jewish friend and his consequent overestimation of both his theoretical and clinical work. Their friendship came to an acrimonious end with Fliess angry at Freud's unwillingness to endorse his general theory of sexual periodicity and accusing him of collusion in the plagiarism of his work. After Fliess failed to respond to Freud's offer of collaboration over the publication of his Three Essays on the Theory of Sexuality in 1906, their relationship came to an end. Development of psychoanalysis In October 1885, Freud went to Paris on a three-month fellowship to study with Jean-Martin Charcot, a renowned neurologist who was conducting scientific research into hypnosis. He was later to recall the experience of this stay as catalytic in turning him toward the practice of medical psychopathology and away from a less financially promising career in neurology research. Charcot specialized in the study of hysteria and susceptibility to hypnosis, which he frequently demonstrated with patients on stage in front of an audience. Once he had set up in private practice back in Vienna in 1886, Freud began using hypnosis in his clinical work. He adopted the approach of his friend and collaborator, Josef Breuer, in a type of hypnosis that was different from the French methods he had studied, in that it did not use suggestion. The treatment of one particular patient of Breuer's proved to be transformative for Freud's clinical practice. Described as Anna O., she was invited to talk about her symptoms while under hypnosis (she would coin the phrase "talking cure"