African Bush Elephant, Bald Eagle, Adelie Penguin, Japanese Gecko, Carolina Anole, and Western Clawed Frog. To make slopes for Fibrinogen (considered a comparatively rapidly evolving protein) and Cytochrome C (comparatively slower), Xenopus tropical, Xenopus laevis, Takifugu rubripes, and Bos Taurus were utilized for comparison. Expression LRRIQ1 is lowly expressed (0.6 times the average gene) in lung, testis, epithelial tissue, pooled germ cell tumors, brain tissues, embryonic tissues, and adipose tissues. Interacting Proteins The presence of the Leucine-Rich Repeat motif provides structural framework for protein-protein interactions. HES4 is the only identified protein that interacts with LRRIQ1. HES4, is a transcription factor found in humans. The protein binds DNA on N-box motifs. Clinical significance To date, the clinical significance of this gene is not known. References Further reading Proteins