Dorry L. Segev is the Israeli-born Marjory K. and Thomas Pozefsky Professor of Surgery at Johns Hopkins School of Medicine, professor of epidemiology at Johns Hopkins Bloomberg School of Public Health, and associate vice chair of the Department of Surgery at Johns Hopkins Hospital. He has made significant contributions to the field of transplantation, including developing a mathematical model to facilitate a nationwide kidney paired donation program, both in the US and Canada. He is also known for his role in getting the HIV Organ Policy Equity Act (or HOPE Act) signed into law. Education and career Segev was born in Haifa, Israel, and earned his B.S. in electrical engineering and B.A. in computer science at Rice University in 1992. He obtained his M.D. at Johns Hopkins University in 1996, as well as his M.H.S. in biostatistics and Ph.D. in clinical investigation at Johns Hopkins Bloomberg School of Public Health in 2009. Both Segev and his wife, Sommer Gentry, have been featured in The Baltimore Sun, Science, Time, and The New York Times. Segev is the director of the Epidemiology Research Group in Organ Transplantation at Johns Hopkins University. Incompatible kidney transplant There are over 20,000 patients on the kidney transplant waitlist who have become highly sensitized, making finding a compatible donor extremely difficult. These patients often spend years on the kidney transplant waitlist looking for a compatible donor. In a 2016 study published in The New England Journal of Medicine, Segev and his team found that patients who received a kidney transplant from an incompatible live donor had a much higher survival benefit compared to patients who stayed on dialysis or waited for a deceased donor transplant. There are over 20,000 patients on the waitlist who have become highly sensitized, meaning that they have developed antibodies human leukocyte antigens—HLAs—key components of the immune system. These findings show that moving forward with a live donor kidney transplant could be the best option for highly sensitized patients who have a healthy and willing donor. Kidney paired donation Kidney paired donation is a form of live donation where patients with incompatible donors swap kidneys to receive a compatible kidney. The first kidney-paired donation was performed in South Korea in 1991, followed by one in Europe in 1999. Sommer Gentry and Dorry Segev found that the existing matching programs were not sufficient to accommodate the scale of the transplant waitlist in the United