the parasites out of Daisy's brain and destroy them, freeing her from Hive's control, but as she escapes, James impales Lash on a fire-charged chain, killing him. Returning to the Playground, Daisy is taken into custody, while May mourns for Andrew. When Talbot reveals that Hydra stole a warhead from the ATCU, Fitz and Simmons deduce that Hive intends to use it to unleash the mutagenic pathogen into Earth's atmosphere. In an end tag Mack, his faith restored, is given a crucifix as a gift by Elena (the same crucifix seen in the vision of the dying S.H.I.E.L.D. agent). Production Development In April 2016, Marvel announced that the twentieth episode of the season would be titled "Emancipation", to be written by Craig Titley, with Vincent Misiano directing. Casting In April 2016, Marvel revealed that main cast members Clark Gregg, Ming-Na Wen, Brett Dalton, Chloe Bennet, Iain De Caestecker, Elizabeth Henstridge, Nick Blood, Adrianne Palicki, Henry Simmons, and Luke Mitchell would star as Phil Coulson, Melinda May, Grant Ward, Daisy Johnson, Leo Fitz, Jemma Simmons, Lance Hunter, Bobbi Morse, Alphonso "Mack" MacKenzie, and Lincoln Campbell, respectively. It was also revealed that the guest cast for the episode would include Axle Whitehead as James, John Hannah as Holden Radcliffe, Natalia Cordova-Buckley as Elena "Yo-Yo" Rodriguez, Adrian Pasdar as Brigadier General Glenn Talbot, Trevor Torseth as Pete Boggs, Jean Paul San Pedro as Jackson, Courtney Friel as newscaster and Jason Sweat as recruit #1. Torseth, Pedro, Friel, and Sweat did not receive guest star credit in the episode. Whitehead, Hannah, Cordova-Buckley, and Pasdar reprise their roles from earlier in the series. Matthew Willig also reprises his role as Lash. Blood and Palicki do not ultimately appear. Marvel Cinematic Universe tie-ins The episode is set in the aftermath of Captain America: Civil War, and deals with how the Inhumans are affected by the Sokovia Accords, with some members of the S.H.I.E.L.D. team feeling "Inhumans should be registered and [others] who feel that's a first step to them being sequestered, imprisoned, exterminated." Bennet said, "we've been dealing with the bigger issues of Civil War on a smaller, more personal scale for a while now. It's been building. We've been having our own mini version of Civil War." Wen noted that "the connection is there, but it’s also very tenuous at this point, because S.H.I.E.L.D. has become so isolated with what’s going on with the Avengers