1861, only two weeks after being mustered out, he was again mustered in as Colonel of what afterwards became the 106th Regiment Pennsylvania Volunteers, but at that time was known as the Fifth California Regiment, of Edward Dickinson Baker's California Brigade. Morehead brought with him numbers of soldiers of the disbanded 22nd Regiment. Morehead shared all the dangers of the men in his 106th Pennsylvania Infantry which went on to serve throughout the whole war. First at Ball's Bluff, then in the Peninsula Campaign where fought at Fair Oaks, Savage Station, Battle of Glendale or Charles City Cross Roads and Malvern Hill. Then he fought at Antietam and Fredericksburg. Although never wounded, Morehead was injured when his horse was shot from under him at Antietam: Colonel Morehead's horse was shot from under him, and, falling, held him fast until released by Sergeant Joseph Taylor and Corporals McNeal and Stephen Taylor of Company C. After going some distance to the rear the Colonel found he had lost his sword, a handsome one, that had been presented to him by the Regiment, and went back after it, though urged not to do so by the men, but he said, "Yes I will, that sword was given me by my men and I told them I would protect it with my life and never see it dishonored, and I am not going to let them damned rebels get it", so he went back to where his horse lay and got it and returned in safety to the regiment although the enemy was near enough to demand his surrender, and fired at him because he refused. Morehead was detailed frequently to the command of different brigades of the II Corps, yet he only received a brevet promotion to brigadier general on March 15, 1865, after he had resigned on April 5, 1864, returning home on account of disabilities caused by disease. Later life After the War General Morehead engaged in the wholesale shoe business until appointed Weigher of the Port of Philadelphia, a position he held for many years. He early entered the Grand Army of the Republic, and became commander of E. D. Baker Post No. 8 of Philadelphia, also a member of the Union Veteran Legion and the Military Order of the Loyal Legion. In 1882, he moved to Asbury Park, New Jersey, where he resided until his death on May 28,