the simpler compound dapsone (which is administered in tablet form). Promin and other sulfones can also not be used as substitutes for dapsone when intolerance develops, as this is a general reaction to sulfones, and not specific to dapsone. Today, the drugs of choice for treating leprosy are dapsone, rifampicin and clofazimine. References Anilines Benzosulfones Dihydropteroate synthetase inhibitors Antileprotic drugs Prodrugs