Alfonso Carrillo de Acuña (1410, in Carrascosa del Campo – 1 July 1482, in Alcalá de Henares) was a Spanish politician and Roman Catholic archbishop. Life His father was Lope Vázquez de Acuña, head of the Honrado Concejo de la Mesta and descendant of a noble Portuguese family. His mother was Teresa Carrillo de Albornoz, a native of Carrascosa del Campo whose ancestors had included clergy. He was educated under his uncle, cardinal Alfonso Carrillo de Albornoz. On Albornoz's fall from power, in 1434, Carrillo was made protonotary apostolic by Pope Eugene IV, entering the royal court of John II of Castile. He was a hugely influential figure in the court of John II (1406–1454), Henry IV (1454–1474) and with the Catholic Monarchs. On the execution of the royal favourite Alvaro de Luna in 1453, Carrillo raised Juan Pacheco, marquis de Villena, the favourite of the new king Henry IV and diplomat to France for him, rising to great power and overcoming many nobles. His greed and ambition led him to oppose the king when Henry IV promoted Beltrán de la Cueva and his Mendoza allies, sworn enemies of Carrillo, as advisors to the throne instead of his nephew, Juan Pacheco. He was made bishop of Sigüenza in 1436 then archbishop of Toledo in 1446. He was made a pseudocardinal deacon of Sant'Eustachio in the consistory of 12 April 1440, but declined the promotion From 1462 Carrillo was the main instigator of the noble Castilian faction which wanted to depose the king and replace him with his half-brother, the infante Alfonso, and he was a highly active participant in the Farce of Ávila. This began a long and bloody civil war in Castile. The infante died in summer 1468 and was replaced as pretender to the throne by his sister Isabella. Carrillo acted as her main advisor and with Pedro de Peralta (Pedro de Peralta y Ezpeleta) he played a major part in arranging her marriage to Ferdinand II of Aragon in October 1469. Even so, when the Catholic Monarchs came to power after Henry IV's death in December 1474, they immediately came into conflict with Carrillo. Carrillo would not accept their authoritarian treatment of him nor his enemy cardinal Pedro González de Mendoza's rise to be chancellor of the kingdom. This led him to clash with the Mendoza family, a battle he lost in the War of the Castilian