After playing some ITF and WTA tournaments, she decided in late February 2013 to take a second break from tennis with no timetable for her return. 2017–18: Return to competition Marino started training again during the first week of September 2017 and decided to return to competition in October 2017, after being away from the game for nearly five years. She was scheduled to play the $60k Saguenay Challenger but her comeback was delayed by three months due to ITF administrative regulations. She returned at a $15k event in Antalya at the end of January 2018 and won the title in her first tournament back, not losing a set along the way. The next week, she won her second straight title at a $15k in Antalya, without losing a set once again. Again in Antalya the week after, she captured her third $15k event in a row. Playing her fourth straight tournament in Antalya, the first on clay, Marino lost her quarterfinal match, ending her winning-streak at 19 matches. At her next tournament in March, a $25k tournament in Kōfu, she reached the quarterfinals as a qualifier but was defeated by world No. 101, Luksika Kumkhum, in three sets. In April at the $25k in Osaka, she advanced to her fourth final of the season where she lost to Destanee Aiava. 2020–21: Hiatus and another comeback to the tour Marino began the season using a protected ranking to gain entry into the qualifying tournament for the 2021 Australian Open, held in Dubai mid-January. She qualified for her first Grand Slam tournament in ten years, defeating Jaqueline Cristian, Viktoriya Tomova and Maryna Zanevska without dropping a set. She was granted direct entry into the Gippsland Trophy, one of three makeshift WTA lead-up tournaments created for the participants of the upcoming Australian Open, also held in Melbourne, however she lost in the first round to Jasmine Paolini. Marino won her first-round match at the Australian Open defeating Kimberly Birrell 6–0, 7–6, but was defeated in the second round by Markéta Vondroušová 6–1, 7–5, despite serving for the second set up 5–3. She won her qualifying match against Mayo Hibi 6–4, 6–3 at the Phillip Island Trophy, another makeshift tournament created in light of the COVID-19 pandemic. In the first round, she beat Mona Barthel to set up a second-round meeting with fourth seeded Petra Martić. 2022: US Open third round At the