He led his American Legion teams to state championships in 2004 and 2007. Gyorko played quarterback and wide receiver for the football team, and shooting guard and point guard for the basketball team. In basketball, Gyorko was named All-Conference as a sophomore. University won the conference championship in Gyorko's junior year, as he averaged 17.4 points per game (PPG), second best in the conference. He was named his conference's Player of the Year and to the All-State second team. In his senior year, he averaged 18.2 PPG and was named to the All-State first team. After weighing scholarship offers to play college baseball from WVU, St. John's University and Clemson University, Gyorko chose to remain near home, enrolling at WVU in order to play college baseball for the West Virginia Mountaineers baseball team, which competed in the Big East Conference of the National Collegiate Athletic Association's (NCAA) Division I. Gyorko shifted to second base for his freshman year to accommodate senior Tyler Kuhn, who played shortstop. He had a 21-game hitting streak to start his tenure with the Mountaineers, registering a .500 batting average during the streak. As a freshman, Gyorko finished the season with a .409 batting average with eight home runs and 63 runs batted in (RBIs), winning the Big East Rookie of the Year Award. He was also named to the All-Big East's second team, and the Freshman All-America teams of Louisville Slugger and the National Collegiate Baseball Writers Association. In 2009, he played collegiate summer baseball for the Brewster Whitecaps of the Cape Cod Baseball League (CCBL), where he was named a league all-star, but he required shoulder surgery and was unable to play the entire summer season. Following Kuhn's graduation, Gyorko returned to shortstop for the Mountaineers. In his sophomore season, Gyorko batted .421 with eight home runs and 58 RBIs. He set a Mountaineers single-season record with 28 doubles. He was named First Team All-Big East and Second Team All-American by Louisville Slugger. After the season, he joined the United States national collegiate baseball team, but did not make the final roster. He joined Brewster for the CCBL season, playing second base. He was named to the CCBL All-Star Team, and he competed in the home run derby, held at Fenway Park. Prior to Gyorko's junior season, in 2010, he was named the preseason Big East Player of the Year and a Third Team