he is informed that he needs to undergo a risky surgery. The night before the operation, Adam argues with an intoxicated Kyle, demanding that he let him drive his car even though he has never learned and has no driver's license. After a near miss, Adam breaks down and accuses Kyle of being more concerned with using the cancer for his own gain than taking his condition seriously. Adam then calls Katherine and tells her he wishes she was his girlfriend, but he also says he is tired of being sick and just wants his cancer to be over. That night, dropping off Kyle (who was too drunk to drive), Adam finds the book Facing Cancer Together from their trip to a bookstore where Kyle picked up a shop clerk. The book is filled with notes, highlighted paragraphs, and turned-down pages. He realizes that Kyle sincerely cares about him and has been earnestly trying to help him since his diagnosis. The next day, Kyle drops Adam off at the hospital, where Adam embraces him for being a good friend and apologizes for the previous night. After saying his tearful farewells to his family, he undergoes surgery. Katherine goes to the waiting room and inadvertently meets Adam's parents and Kyle during the wait. After the surgery, they are told that although the bone degradation was worse than they believed, the surgeons removed the tumor successfully, and Adam will recover. Sometime later, he is preparing for a date with Katherine, while Kyle encourages him and bandages the incision on his back. After Kyle leaves, Katherine asks, "Now what?" and Adam smiles, finally free of cancer. Cast Development and production The screenplay is loosely based on the experience of screenwriter Will Reiser, friend of the film's co-lead, Seth Rogen. Reiser is also close with Evan Goldberg of Da Ali G Show. The film was going to be called I'm with Cancer before it was announced that this was a working title. The film was later renamed Live with It and then 50/50. James McAvoy was going to play the lead role before he left the film due to personal reasons, as he was afraid of missing the birth of his first child, and was replaced by Joseph Gordon-Levitt. Principal photography took place in Vancouver over a five-week period, beginning in March 2010. The head-shaving scene in the film was featured on the movie