passed for two touchdowns to lead Northwestern to a 29–28 win. The Wildcats overcame a 25-point deficit, which was the biggest comeback in school history. He went 26-of-46 and passed for 312 yards, along with two touchdowns and a career-tying three interceptions. He rushed for 65 yards on 17 carries and one touchdown. Kafka totaled 377 yards of total offense, which was second-best in his career. Against 12th ranked Penn State, Kafka went 14-for-18 and passed for 128 yards, along with rushing for 42 yards on eight carries and a touchdown before leaving the game with a leg injury during the second quarter. He was replaced by backup Dan Persa. Kafka shared time at quarterback with Persa due to his strained hamstring on November 7 against the 4th-ranked, and previously undefeated, Iowa Hawkeyes. Northwestern coming into the game was a 16-point underdog, but still beat Iowa 17–10 in Northwestern's first win over a nationally ranked top-ten team since they won against Ohio State in 2004. Persa had to leave the game early to receive X-rays for a hand injury, which forced Kafka to play more than original planned. He finished as Northwestern’s leading passer with 72 yards on ten completions. Against Illinois on November 14, Kafka threw for 305 yards and went 23-of-37, along with a 28-yard touchdown pass to wide receiver Zeke Markshausen. He rushed seven times for 12 yards and a one-yard touchdown to beat the Fighting Illini 21–16. Kafka threw for 300 or more yards for the fourth time that season. Against 16th-ranked Wisconsin on November 21, Kafka went 26-of-40 for 326 yards and two touchdowns, both to converted wide receiver Andrew Brewer. He rushed for 17 yards on seven carries to upset the Badgers with a 33–31 win. Kafka threw for 300 or more yards for the fifth time in the season and for the second straight game. He was named Big Ten Co-Offensive Player of the Week for his performance against Wisconsin. Kafka ranked third in the Big Ten Conference in passing yards with 241.5 passing yards per game and he ranked second in total offense. He finished the season tied for first in the Big Ten in rushing touchdowns by a quarterback with seven. His 65.7 completion percentage for 2009 ranked first in the Big Ten. His 414 pass attempts ranked third in the Big Ten and eighth among all quarterbacks nationally. Kafka was