particular enzymatic defect. She was the first to show that a defect in an enzyme can be the cause of a human genetic disease. Gerty and Carl Cori collaborated on most of their work, including that which won them the 1947 Nobel Prize in Physiology or Medicine "for their discovery of the course of the catalytic conversion of glycogen". They received one half the prize, the other half going to the Argentinian physiologist, Bernardo Houssay "for his discovery of the part played by the hormone of the anterior pituitary lobe in the metabolism of sugar". Their work continued to clarify the mechanisms of carbohydrate metabolism, advancing understanding of the reversible conversion of sugars and starch, findings which proved crucial in the development of treatments for diabetics. Awards and recognitions In 1947, Gerty Cori became the third woman—and the first American woman—to win a Nobel Prize in science, the previous recipients being Marie Curie and Irène Joliot-Curie. She was the first woman to be awarded the Nobel Prize in Physiology or Medicine. She was elected a Fellow of the American Academy of Arts and Sciences in 1953. Cori was the fourth women elected to the National Academy of Sciences. She was appointed by President Harry S. Truman as board member of the National Science Foundation, a position she held until her death. Gerty was also a member of the American Society of Biological Chemists, the American Chemical Society and the American Philosophical Society. She and her husband were presented jointly with the Midwest Award (American Chemical Society) in 1946 and the Squibb Award in Endocrinology in 1947. In addition, Cori received the Garvan-Olin Medal (1948), the St. Louis Award (1948), the Sugar Research Prize (1950), the Borden Award (1951). The twenty-five square foot laboratory shared by Cori and her husband at Washington University was deemed a National Historic Landmark by the American Chemical Society in 2004. Six of the scientists mentored by Cori and her husband went on to win Nobel Prizes, which is only surpassed by the mentored scientists of British physicist J.J. Thomson. In 1949, she was awarded the Iota Sigma Pi National Honorary Member for her significant contribution. The crater Cori on the Moon is named after her, as is the Cori crater on Venus. She shares a star with her husband on the St. Louis Walk of Fame. She was inducted into the National Women's Hall of