as acitretin, etretinate, and isotretinoin, for the treatment of keratoderma and, less effectively, for periodontitis. Topical emollients, salicylic acid and urea preparations can also be used as adjuncts. Extraction of the primary teeth combined with oral antibiotics and professional teeth cleaning, for periodontitis. It has been reported that Inflammation associated with the arthritis caused by HMS can be controlled by removal of the synovial tissue surrounding affected joints (synovectomy), at the cost of permanent handicap. See also Ichthyosis–sclerosing cholangitis syndrome List of cutaneous conditions List of dental abnormalities associated with cutaneous conditions References External links Genodermatoses Palmoplantar keratodermas Syndromes affecting teeth Syndromes affecting the skin Rare syndromes