between the two Greek powers Athens and Sparta. Athens built a long wall to protect its inhabitants, but the wall helped to facilitate the spread of a plague that killed about 30,000 Athenians, including Pericles. After a disastrous campaign against Syracuse, the Athenian navy was decisively defeated by Lysander at the Battle of Aegospotami. The Macedonians, underneath Philip II of Macedon and Alexander the Great, invaded Persia and won several major victories, establishing Macedonia as a major power. However, following Alexander's death at an early age, the empire quickly fell apart. Meanwhile, Rome was gaining power, following a rebellion against the Etruscans. During the three Punic Wars, the Romans defeated the neighboring power of Carthage. The First Punic War centered on naval warfare. The Second Punic War started with Hannibal's invasion of Italy by crossing the Alps. He famously won the encirclement at the Battle of Cannae. However, after Scipio invaded Carthage, Hannibal was forced to follow and was defeated at the Battle of Zama, ending the role of Carthage as a power. After defeating Carthage the Romans went on to become the Mediterranean's dominant power, successfully campaigning in Greece, (Aemilius Paulus decisive victory over Macedonia at the Battle of Pydna), in the Middle East (Lucius Licinius Lucullus, Gnaeus Pompeius Magnus), in Gaul (Gaius Julius Caesar) and defeating several Germanic tribes (Gaius Marius, Germanicus). While Roman armies suffered several major losses, their large population and ability (and will) to replace battlefield casualties, their training, organization, tactical and technical superiority enabled Rome to stay a predominant military force for several centuries, utilizing well trained and maneuverable armies to routinely overcome the much larger "tribal" armies of their foes (see Battles of Aquae Sextiae, Vercellae, Tigranocerta, Alesia). In 54 BC the Roman triumvir Marcus Licinius Crassus took the offensive against the Parthian Empire in the east. In a decisive battle at Carrhae Romans were defeated and the golden Aquilae (legionary battle standards) were taken as trophies to Ctesiphon. The battle was one of the worst defeats suffered by the Roman Republic in its entire history. While successfully dealing with foreign opponents, Rome experienced numerous civil wars, notably the power struggles of Roman generals such as Marius and Sulla during the end of the Republic. Caesar was also notable for his role in the civil war against the other member of the Triumvirate (Pompey) and against the Roman Senate. The successors of Caesar