antagonists, and/or a proton pump inhibitor. Sucralfate was used as an option. Parenteral nutrition greatly increased chance of recovery. An esophagectomy can be issued if the disorder is severe enough. Prognosis The prognosis for acute esophageal necrosis is generally poor, as the condition is associated with a high risk of mortality (up to 32%). Most mortality is attributed to the underlying cause; mortality specifically caused by AEN is about 6 percent. Society and culture Acute esophageal necrosis made an appearance on an American medical drama show, Dr. G: Medical Examiner. Jan Garavaglia, the show's host, receives a female body, that at time of the autopsy had a severe case of acute esophageal necrosis due to alcohol use disorder. History Acute esophageal necrosis was first described by Goldenberg et al. in 1990. Cases have emerged since 1960, but have never been described as the common names for AEN. Due to its rarity, only 88 cases have been pronounced AEN, but most likely there are many more. Gurvits et al. describes AEN as "poorly described in medical literature". Abdullah et al. published the first-ever systemic review on acute esophageal necrosis and reviewed around 154 patients reported in the literature at the time of publishing. References External links Esophagus disorders