range of relevant issues including genetics in healthcare, the use of bioinformation, and concerns surrounding consent and confidentiality. Information technology and research infrastructure Biobank projects require considerable infrastructure to ensure that samples and data gathered from volunteers at the various recruitment centres are collected efficiently, processed and stored securely, and analysed effectively. Generation Scotland has designed protocols to standardise and integrate all stages of the process from volunteer recruitment to data handling. For example, a customised Laboratory Information Management System (LIMS) is being used to track samples as they move from the clinics to the Wellcome Trust Clinical Research Facility, Edinburgh for processing and storage, and then on to the research laboratories for analysis. Timeline The Generation Scotland concept has evolved over many years. Below is a list of the key milestones in the development of Generation Scotland and its associated projects. 2020 New GS branding developed by the team for new study. Due to the Coronavirus (COVID-19) outbreak, they also began new research into the Government's regulations and their impact on mental health and well being. The new study is called CovidLife 2019 GS help in research to find 102 genes linked to depression and evidence of heart injury. Later in the year they were awarded funding to enrol another 20,000 volunteers into the study 2018 300th research application received and volunteers are celebrated for their contribution to Scottish research 2017 GS co-authors over 150 research papers 2016 GS organises a symposium in Edinburgh, co-sponsored by the Centre for Cognitive Ageing and Cognitive Epidemiology. 2015 New data collection for GS:SFHS starts through the Stratifying Resilience and Depression Longitudinally (STRaDL) project. 2014 Genetic annotation of 20,000 GS:SFHS participants is completed. GS co-authors its 50th research paper. 2013 GS:SFHS cohort description is published in the International Journal of Epidemiology. Genetic annotation of 10,000 GS:SFHS participants is completed. GS organises a symposium co-hosted by Health Science Scotland in Surgeons' Hall, Edinburgh. 2012 GS receives its 100th research collaboration proposal. GS organises a successful GS Symposium in March, sponsored and hosted by Health Science Scotland and Nexxus, held in Glasgow. In February, a partnership is formed with Health Science Scotland (HSS). 2011 GS:21CGH receives favourable ethical opinion from NHS research ethics committee for setting up a Research Tissue Bank. Generation Scotland is awarded further funding from the Chief Scientist Office in April. In March, the final GS:SFHS participants attend a clinic, bringing the