26 | December 23 | Portland | | Tim Duncan (24) | Tim Duncan (11) | Tony Parker, Manu Ginóbili, George Hill, Roger Mason, Jr. (4) | AT&T Center18,581 | 15–11 |- bgcolor="#bbffbb" | 27 | December 26 | @ Milwaukee | | Tim Duncan (26) | DeJuan Blair (12) | Tony Parker, Manu Ginóbili (8) | Bradley Center14,864 | 16–11 |- bgcolor="#bbffbb" | 28 | December 27 | @ New York | | Tony Parker (22) | DeJuan Blair (10) | Richard Jefferson (4) | Madison Square Garden19,763 | 17–11 |- bgcolor="#bbffbb" | 29 | December 29 | Minnesota | | Richard Jefferson (24) | Tim Duncan (10) | Manu Ginóbili (10) | AT&T Center18,581 | 18–11 |- bgcolor="#bbffbb" | 30 | December 31 | Miami | | Tim Duncan (23) | Tim Duncan (10) | Tony Parker (9) | AT&T Center18,581 | 19–11 |- bgcolor="#bbffbb" | 31 | January 2 | @ Washington | | Tim Duncan (23) | Tim Duncan (7) | Tony Parker (7) | Verizon Center19,025 | 20–11 |- bgcolor="#ffcccc" | 32 | January 3 | @ Toronto | | Tony Parker (23) | Tim Duncan (12) | Tony Parker (6) | Air Canada Centre18,323 | 20–12 |- bgcolor="#bbffbb" | 33 | January 6 | Detroit | | Tony Parker (23) | DeJuan Blair (8) | Tony Parker (6) | AT&T Center17,337 | 21–12 |- bgcolor="#ffcccc" | 34 | January 8 | Dallas | | Tim Duncan (31) | Tim Duncan (12) | Manu Ginóbili (7) | AT&T Center18,581 | 21–13 |- bgcolor="#bbffbb" | 35 | January 10 | New Jersey | | Manu Ginóbili (21) | Tim Duncan (17) | Tony Parker (5) | AT&T Center18,047 | 22–13 |- bgcolor="#bbffbb" | 36 | January 12 | L.A Lakers | | Tim Duncan (25) | Tim Duncan (13) | Tony Parker, Manu Ginóbili (6) | AT&T Center18,581 | 23–13 |- bgcolor="#bbffbb" | 37 | January 13 | @ Oklahoma City | (OT) | Tony Parker, DeJuan Blair (28) | DeJuan Blair (21) | Tony Parker (8) | Ford Center17,886 | 24–13 |- bgcolor="#ffcccc" | 38 | January 15 | @ Charlotte | | Tony Parker, DeJuan Blair, George Hill, Manu Ginóbili (11) | DeJuan Blair (16) | Tim Duncan (5) | Time Warner Cable Arena15,742 | 24–14 |- bgcolor="#ffcccc" | 39 | January 16 | @ Memphis | | Tim Duncan (23) | DeJuan Blair,