the tongue representation is bilateral in both modalities, but predominantly ipsilateral in the gustatory modality and predominantly contralateral in the tactile modality. The absence of left gustatory extinction in those patients can be attributed to the predominant channeling of left hemitongue taste inputs into the intact left hemisphere. Since there were no severe disturbances manifested in any of the present RHD or LHD patients, it seems reasonable to assume that gustatory extinction surfaces only as an accompaniment and possibly a consequence of a very marked extinction of tactile lingual sensitivity, or even a full blown intraoral tactile hemineglect. There is still no clear evidence of the existence of purely taste extinction and/or neglect. More evidence that suggests the relationship between tactile and taste extinction in the tongue comes from a patient with a right parieto-occipital glioblastoma, tested with local applications of the four basic tastants (bitter, salty, sour, sweet), or with touch and pin prick stimuli to the two sides of the tongue. The patient missed most of the left hemitongue stimuli on bilateral stimulation, or less frequently wrongly attributed to them the quality of the concurrent right stimulus. Combinations of taste and mechanical stimuli showed an interference of left side stimuli on the perception of right stimuli, suggesting a complex alteration of the central tactile and gustatory representations of both sides of the tongue. Given that taste perception is usually co-mingled with tactile sensations, it is possible that left-sided gustatory extinction in severe left buccal hemineglect was secondary to left-sided lingual tactile extinction. Multisensory Neglect and extinction can overlap for a single sensory modality, and even for multiple sensory modalities. Extinction affecting a unimodal sensory system can be influenced by the concurrent activation of another modality. Tactile extinction, as an example, can be modulated by visual events simultaneously presented in the region near the tactile stimulation, increasing or reducing tactile perception, depending upon the spatial arrangement of the stimuli. In one example of visual and tactile relationship, the visual stimulation in the ipsilesional side exacerbates contralesional tactile extinction, whereby the presentation of visual and tactile stimuli on the same contralesional side can reduce the deficit. Tactile and visual informations can also be integrated in other peripersonal space regions, such as around the face. Another similar modulation interaction is between audition and touch. The contralesional tactile detection is hampered by sounds in tactile extinction patients. However, a multisensory effect observed