| 7 | November 6 | Phoenix | | Kevin Garnett (26) | Kevin Garnett (8) | Rajon Rondo (11) | TD Garden 18,624 | 6–1 |- bgcolor="#bbffbb" | 8 | November 7 | @ New Jersey | | Paul Pierce, Rajon Rondo (16) | Kevin Garnett (13) | Paul Pierce (7) | Izod Center 16,119 | 7–1 |- bgcolor="#bbffbb" | 9 | November 11 | Utah | | Kevin Garnett (18) | Kendrick Perkins (8) | Rajon Rondo (11) | TD Garden 18,624 | 8–1 |- bgcolor="#ffcccc" | 10 | November 13 | Atlanta | | Paul Pierce (24) | Kendrick Perkins (9) | Rajon Rondo (9) | TD Garden18,624 | 8–2 |- bgcolor="#ffcccc" | 11 | November 14 | @ Indiana | | Ray Allen (24) | Kendrick Perkins (13) | Paul Pierce, Rajon Rondo, Ray Allen (4) | Conseco Fieldhouse18,165 | 8–3 |- bgcolor="#bbffbb" | 12 | November 18 | Golden State | | Paul Pierce (19) | Kendrick Perkins, Rajon Rondo (7) | Rajon Rondo (12) | TD Garden18,624 | 9–3 |- bgcolor="#ffcccc" | 13 | November 20 | Orlando | | Paul Pierce (21) | Rasheed Wallace (13) | Ray Allen, Rajon Rondo (6) | TD Garden18,624 | 9–4 |- bgcolor="#bbffbb" | 14 | November 22 | @ New York | | Paul Pierce (33) | Kendrick Perkins (13) | Rajon Rondo (10) | Madison Square Garden19,763 | 10–4 |- bgcolor="#bbffbb" | 15 | November 25 | Philadelphia | | Paul Pierce (27) | Kendrick Perkins (8) | Rajon Rondo (7) | TD Garden18,624 | 11–4 |- bgcolor="#bbffbb" | 16 | November 27 | Toronto | | Ray Allen (20) | Kevin Garnett (7) | Rajon Rondo (11) | TD Garden18,624 | 12–4 |- bgcolor="#bbffbb" | 17 | November 29 | @ Miami | | Kevin Garnett (24) | Kendrick Perkins (13) | Rajon Rondo (11) | American Airlines Arena18,104 | 13–4 |- bgcolor="#bbffbb" | 18 | December 1 | @ New Orleans | | Ray Allen (27) | Kendrick Perkins (12) | Rajon Rondo (9) | Time Warner Cable Arena15,129 | 14–4 |- bgcolor="#bbffbb" | 19 | December 3 | @ San Antonio | | Kevin Garnett (20) | Kevin Garnett, Kendrick Perkins (7) | Rajon Rondo (12) | AT&T Center18,581 | 15–4 |- bgcolor="#bbffbb" | 20 | December 4 | @ Oklahoma City | | Kevin Garnett (23) | Kevin Garnett, Kendrick Perkins