2002 stock collapse was not caused by the farm sea lice population: although the farm sea lice population during the out-migration of juvenile pink salmon was greater in 2000 than that of 2001, there was a record salmon returning to spawn in 2001 (from the juveniles in 2000) compared with a 97% collapse in 2002 (from the juveniles in 2001). The authors also note that initial studies had not investigated bacterial and viral causes for the event despite reports of bleeding at the base of the fins, a symptom often associated with infections, but not with sea lice exposure under laboratory conditions. Wild salmon are anadromous. They spawn inland in fresh water and when young migrate to the ocean where they grow up. Most salmon return to the river where they were born, although some stray to other rivers. Concern exists about of the role of genetic diversity within salmon runs. The resilience of the population depends on some fish being able to survive environmental shocks, such as unusual temperature extremes. The effect of hatchery production on the genetic diversity of salmon is also unclear. Genetic modification Salmon have been genetically modified in laboratories so they can grow faster. A company, Aqua Bounty Farms, has developed a modified Atlantic salmon which grows nearly twice as fast (yielding a fully grown fish at 16–18 months rather than 30), and is more disease resistant, and cold tolerant. It also requires 10% less food. This was achieved using a chinook salmon gene sequence affecting growth hormones, and a promoter sequence from the ocean pout affecting antifreeze production. Normally, salmon produce growth hormones only in the presence of light. The modified salmon does not switch growth hormone production off. The company first submitted the salmon for FDA approval in 1996. In 2015, FDA has approved the AquAdvantage Salmon for commercial production. A concern with transgenic salmon is what might happen if they escape into the wild. One study, in a laboratory setting, found that modified salmon mixed with their wild cohorts were aggressive in competing, but ultimately failed. Impact on wild predatory species Sea cages can attract a variety of wild predators which can sometimes become entangled in associated netting, leading to injury or death. In Tasmania, Australian salmon-farming sea cages have entangled white-bellied sea eagles. This has prompted one company, Huon Aquaculture, to sponsor a bird rehabilitation centre and try more robust netting.