Toyota Center18,119 | 20–22 |- bgcolor="#bbffbb" | 43 | January 25 | @ San Antonio | | Derrick Rose (27) | Luol Deng (9) | Derrick Rose (6) | AT&T Center18,581 | 21–22 |- bgcolor="#bbffbb" | 44 | January 27 | @ Oklahoma | | Derrick Rose (26) | Taj Gibson (15) | Derrick Rose (7) | Ford Center17,562 | 22–22 |- bgcolor="#bbffbb" | 45 | January 29 | @ New Orleans | | Luol Deng (26) | Joakim Noah (18) | Kirk Hinrich (6) | New Orleans Arena16,578 | 23–22 |- bgcolor="#ffcccc" | 46 | February 2 | L.A. Clippers | | Luol Deng (18) | Tyrus Thomas (9) | Derrick Rose (4) | United Center19,335 | 23–23 |- bgcolor="#ffcccc" | 47 | February 3 | @ Philadelphia | | Derrick Rose (30) | Luol Deng (11) | Derrick Rose (9) | Wachovia Center13,295 | 23–24 |- bgcolor="#ffcccc" | 48 | February 5 | @ Atlanta | | Luol Deng (20) | Kirk Hinrich (9) | Derrick Rose (6) | Philips Arena18,729 | 23–25 |- bgcolor="#bbffbb" | 49 | February 6 | Miami | | Luol Deng (25) | Brad Miller (8) | John Salmons (5) | United Center22,352 | 24–25 |- bgcolor="#bbffbb" | 50 | February 9 | @ Indiana | | Luol Deng (23) | Luol Deng (11) | Derrick Rose (7) | Conseco Fieldhouse12,945 | 25–25 |- bgcolor="#ffcccc" | 51 | February 10 | Orlando | | Luol Deng (23) | Luol Deng (7) | Kirk Hinrich, Tyrus Thomas (4) | United Center21,566 | 25–26 |- bgcolor="#bbffbb" | 52 | February 16 | New York | | Derrick Rose (29) | Taj Gibson (10) | Kirk Hinrich, Derrick Rose, John Salmons (6) | United Center20,989 | 26–26 |- bgcolor="#bbffbb" | 53 | February 17 | @ New York | | Derrick Rose (27) | Taj Gibson (16) | Derrick Rose (6) | Madison Square Garden19,763 | 27–26 |- bgcolor="#bbffbb" | 54 | February 19 | @ Minnesota | | Kirk Hinrich (20) | Brad Miller (10) | Kirk Hinrich, Derrick Rose (5) | Target Center18,183 | 28–26 |- bgcolor="#bbffbb" | 55 | February 20 | Philadelphia | | Taj Gibson (20) | Taj Gibson (13) | Derrick Rose (6) | United Center22,147 | 29–26 |- bgcolor="#ffcccc" | 56 | February 22 | @ Washington | | Derrick Rose (22) | Taj Gibson (8) | Derrick Rose