Myrsine lessertiana, the kōlea lau nui, is a species of colicwood that is endemic to Hawaii. It inhabits dry, coastal mesic, mixed mesic, and wet forests at elevations of on all main islands. M. lessertiana is a small to medium-sized tree, reaching a height of and a trunk diameter of . Uses Native Hawaiians used kōlea lau nui wood to make papa olonā (Touchardia latifolia scrapers), kua kuku (kapa anvils), pou (house posts), kaola (beams) and pale (gunwales) and manu (ornamental end pieces) for waa (outrigger canoes). Kōlea lau nui bark was boiled in water to make hili kōlea (a red dye), which was then used on kapa. Its leaves have been used for visions and revelation, and when smoked produce a high euphoric effect and visuals similar to those of LSD. References lessertiana Plants described in 1841 Endemic flora of Hawaii Trees of Hawaii Flora without expected TNC conservation status