The La Crosse–Onalaska Metropolitan Statistical Area, as defined by the United States Census Bureau, is an area consisting of La Crosse County, Wisconsin and Houston County, Minnesota, anchored by the cities of La Crosse and Onalaska. The area is part of what is commonly referred to as the Coulee Region or 7 Rivers Region. As of the 2020 census, the MSA had a population of 139,627, and in 2021 estimates placed the total population at 139,211. Counties La Crosse County Wisconsin Houston County, Minnesota Communities Places with more than 50,000 inhabitants La Crosse, WI (Principal city) Places with 10,000 to 50,000 inhabitants Onalaska, WI (Principal city) Holmen, WI Places with 5,000 to 10,000 inhabitants La Crescent, MN West Salem, WI Places with 1,000 to 5,000 inhabitants Bangor, WI Caledonia, MN Spring Grove, MN Places with fewer than 1,000 inhabitants Brownsville, MN Eitzen, MN Hokah, MN Houston, MN Rockland, WI Unincorporated places Barre Mills, WI Burns, WI Campbell, WI Farmington, WI French Island, WI Greenfield, WI Hamilton, WI Holland, WI Medary, WI Mindoro, WI Shelby, WI Stevenstown, WI Washington, WI Population Cities Primary Onalaska was promoted as a principal city of the MSA when the Office of Management and Budget revised the definitions of metropolitan statistical areas in 2013. See also Wisconsin statistical areas References External links La Crosse County Houston County La Crosse, Wisconsin La Crosse County, Wisconsin Houston County, Minnesota