the final at the 2021 Winston-Salem Open with new partner Austin Krajicek. At the 2021 BNP Paribas Open in Indian Wells, he reached his second Masters 1000 semifinal for 2021 after reuniting with Marcelo Melo where they were defeated by the eventual champions, his former partner Polasek and John Peers. Seeded as a top pair, Dodig and Melo reached the quarterfinals at the 2021 European Open. 2022: Australian Open mixed doubles title, French Open runner-up, 20th title Dodig partnering Kristina Mladenovic won the mixed doubles event at the 2022 Australian Open. It was his second title at this Major and sixth Grand Slam title overall. Partnering with Austin Krajicek they won their first title as a pair at the 2022 ATP Lyon Open, having reached the final at the 2021 Winston-Salem Open previously together. At the 2022 French Open he reached his fourth Grand Slam doubles final in his career also partnering with Krajicek defeating en route World No. 1 and No. 2 and top seeds Joe Salisbury and Rajeev Ram and saving five match points in the quarterfinals. They lost to Marcelo Arevalo and Jean Julien Rojer in the final. At the 2022 Halle Open and the 2022 Eastbourne International he reached the semifinals with Krajicek. At the ATP 500 2022 Citi Open, he reached his 40th doubles career final. Then, he reached his 41th at the 2022 Firenze Open defeating Nicolas Mahut and Édouard Roger-Vasselin. At the 2022 Tennis Napoli Cup he won his second title with Krajicek as a team defeating home favorites Lorenzo Sonego / Andrea Vavassori to reach their fifth final of 2022 and Australian duo Matthew Ebden/John Peers in the final. He reached his third straight and sixth final for the season with Krajicek at the ATP 500 2022 Swiss Indoors in Basel defeating top seeds Arevalo/Rojer and the Kazakhstani duo of Andrey Golubev and Aleksandr Nedovyesov en route. The team won their third title together defeating Mahut/Roger-Vasselin. At the 2022 Rolex Paris Masters the pair Dodig/Krajicek reached the semifinals defeating Belgian pair Sander Gille/Joran Vliegen and top seeds Rajeev Ram/Joe Salisbury climbing to World No. 9 and World No. 10 respectively. On 5 November, the pair qualified for the 2022 ATP Finals after defeating German duo Kevin Krawietz and Andreas Mies to reach their seventh final of 2022 as a team and eight for Dodig. Dodig reached world No. 8 in the rankings