$240–$280 million facility and half will pay for research, on the condition that MIT builds the center even if fund raising falls short. Mission The Koch Institute emphasizes basic research into how cancer is caused, progresses, and responds to treatment. Unlike many other NCI Cancer Centers, it will not provide medical care or conduct clinical research but it has partnered with oncology centers such as the Massachusetts General Hospital's Cancer Center. The institute combines the existing faculty of the CCR with an equivalent number of engineering faculty to promote interdisciplinary approaches to diagnosing, monitoring, and treating cancer. The Koch Institute has identified five areas of research that it believes are critical for controlling cancer: Developing nanotechnology-based cancer therapeutics, creating novel devices for cancer detection and monitoring, exploring the molecular and cellular basis of metastasis, advancing personalized medicine through analysis of cancer pathways and drug resistance, engineering the immune system to fight cancer. Affiliates The Koch Institute is home to faculty members from various departments, including Biology, Chemistry, Mechanical Engineering, and Biological Engineering; more than 40 laboratories and 500 researchers across the campus. Koch Institute faculty teach classes at MIT, as well as train graduate and undergraduate students as well as postdoctoral fellows. The Koch Institute is affiliated with two current Nobel Laureates (Horvitz and Sharp), eighteen members of the National Academy of Sciences, eight members of the National Academy of Engineering, five National Medal of Science laureates, and ten Howard Hughes Medical Institute investigators, and one MacArthur Foundation Fellowship recipient. Notable faculty members affiliated with the Koch Institute include: Building The research facility is located on the corner of Main Street and Ames Street near Kendall Square in Cambridge, Massachusetts. The building is located opposite the Whitehead Institute and Broad Institute and near the biology and chemical engineering buildings on the north-eastern end of MIT's campus. MIT broke ground on Building 76 in March 2008, a topping-off ceremony was held in February 2009, and the building was dedicated on March 4, 2011. The building was designed by Cambridge-based architecture firm Ellenzweig, which designed several other buildings on the MIT campus. The structural engineer was LeMessurier. Designed to encourage interaction and collaboration, the building employs both dedicated lab space as well as common areas, and features a ground-floor gallery exhibiting art and technical displays related to biomedical research. The building includes facilities for bioinformatics and computing, genomics, proteomics and flow cytometry,