State Route 133 (SR 133) is a mostly multi-lane state highway and is a primary artery through the Florence–Muscle Shoals metropolitan area in the northwestern part of the U.S. state of Alabama. Route description SR 133 begins at an intersection with US 72 Alternate/SR 20/SR 157 just south of Muscle Shoals, in Colbert County. Here, the roadway continues as Colbert County Route 57 (CR 57) SR 133 and SR 157 travel concurrently to the north along Wilson Dam Road. They cross over Dry Creek and then enter the city limits of Muscle Shoals. They travel underneath a railroad bridge that carries railroad tracks of Norfolk Southern Railway. After that, they briefly leave the city limits. After they re-enter the city, they intersect Colbert CR 24 (CR 24; 6th Street). The road becomes a six-lane highway at Avalon Avenue. There is an intersection with SR 184 (East 2nd Street) just before a crossing of Pond Creek. They curve to the northwest and then cross the Tennessee River on the Singing River Bridge. They enter Lauderdale County and the city limits of Florence. Almost immediately, SR 133 splits off from SR 157 at an interchange. It travels to the northeast on Veterans Drive. It passes the Shoals Chamber of Commerce and the River Heritage Park. Just after passing Veterans Park, the highway curves to a nearly due north direction. At an intersection with the western terminus of Lauderdale CR 32 (Huntsville Road), SR 133 curves to the north-northwest. It has an intersection with US 43/US 72 (internally designated as SR 2)/SR 13 (Florence Boulevard). The highway curves to the northwest. It begins to travel along the northern edge of Delbert Park; on the northern edge of the park is an intersection with the western terminus of Lauderdale CR 46 (Gresham Road). On the northwestern edge of the park, after SR 133 has curved to a due west direction, it has an intersection with both the southern terminus of Lauderdale CR 47 (Old Jackson Highway South) and the northern terminus of Darby Drive. Just after curving to the west-southwest, it begins a concurrency with SR 17/SR 157 (Helton Drive). Almost immediately, the three highways cross over some railroad tracks of CSX. A short distance later, SR 17 splits off to the north onto Chisolm Road, while SR 133 and SR 157 travel to the southwest. They travel along the northern edge of Cox