for Tregs and suppression of immune system. IL-2Rα subunit expression on Tregs secures better sensitivity to IL-2. Therefore, administration of low doses of the cytokine preferentially stimulates T regulatory cells over others. Low-dose IL-2 therapy is used for graft-versus-host disease, type 1 diabetes mellitus, hepatitis C virus-induced vasculitis and systemic lupus. References Further reading External links Mouse CD Antigen Chart Human CD Antigen Chart CD4+FoxP3+ regulatory T cells gradually accumulate in gliomas during tumor growth and efficiently suppress antiglioma immune responses in vivo Clusters of differentiation