|| 4–12 || Ol. Perez || Suppan || || 16,682 || 8–6 |- style="background-color:#bbffbb" | 15 || April 19 || @ Pirates || 4–0 || Carpenter || Santos || || 15,085 || 9–6 |- style="background-color:#bbffbb" | 16 || April 21 || Cubs || 9–3 || Mulder || Williams || || 41,379 || 10–6 |- style="background-color:#bbffbb" | 17 || April 22 || Cubs || 4–1 || Ponson || Rusch || Isringhausen || 41,424 || 11–6 |- style="background-color:#ffbbbb" | 18 || April 23 || Cubs || 3–7 || Maddux || Marquis || || 41,373 || 11–7 |- style="background-color:#bbffbb" | 19 || April 24 || Pirates || 7–2 || Carpenter || Ol. Perez || || 38,953 || 12–7 |- style="background-color:#bbffbb" | 20 || April 25 || Pirates || 6–3 || Suppan || Santos || Isringhausen || 38,809 || 13–7 |- style="background-color:#bbffbb" | 21 || April 26 || Pirates || 4–3 || Isringhausen || R. Hernandez || || 38,728 || 14–7 |- style="background-color:#bbffbb" | 22 || April 27 || Nationals || 6–2 || Ponson || O'Connor || || 39,515 || 15–7 |- style="background-color:#ffbbbb" | 23 || April 28 || Nationals || 3–8 || Armas || Marquis || || 40,841 || 15–8 |- style="background-color:#bbffbb" | 24 || April 29 || Nationals || 2–1 || Looper || Rauch|| Isringhausen || 39,596 || 16–8 |- style="background-color:#bbffbb" | 25 || April 30 || Nationals || 9–2 || Suppan || Day || || 39,383 || 17–8 |- style="background-color:#ffbbbb" | 26 || May 1 || @ Reds || 1–6 || Arroyo || Mulder || || 20,900 || 17–9 |- style="background-color:#ffbbbb" | 27 || May 2 || @ Reds || 2–3 || Coffey || Falkenborg || || 25,127 || 17–10 |- style="background-color:#ffbbbb" | 28 || May 3 || @ Astros || 4–5 || Oswalt || Marquis || Lidge || 37,305 || 17–11 |- style="background-color:#ffbbbb" | 29 || May 4 || @ Astros || 3–4 || Pettitte || Carpenter || Lidge || 37,290 || 17–12 |- style="background-color:#bbffbb" | 30 || May 5 || @ Marlins || 7–2 || Suppan || Mitre || || 13,266 || 18–12 |- style="background-color:#bbffbb" | 31 || May 6 || @ Marlins || 7–6 || Mulder || Willis || Isringhausen || 14,369 || 19–12 |- style="background-color:#bbffbb" | 32 || May 7 || @ Marlins || 9–1 || Hancock || Olsen || || 13,057 || 20–12 |- style="background-color:#ffbbbb" | 33 || May 8 || Rockies || 2–6 || Francis