in thrombosis and have been associated with stroke. These observations suggest that NETs might play an important role in the pathogenesis of infectious, inflammatory and thrombotic disorders. Due to the charged and 'sticky' nature of NETs, they may become a problem in cystic fibrosis sufferers, by increasing sputum viscosity. Treatments have focused on breaking down DNA within sputum, which is largely composed of host NET DNA. A small study published in the journal JAMA Cardiology suggested that NETs played a major role in COVID-19 patients who developed ST-elevation myocardial infarctions. References External links Frontiers in Molecular Innate Immunity research topic about NET "Molecular mechanisms involved in neutrophil extracellular trap (NET) formation", PhD thesis, Jyaysi Desai, Ludwig Maximilian University of Munich, Germany. Chemistry winner, Dance Your PhD, 2015. Cell biology Immune system