advisory board included behavioral neurologist António Damásio, cognitive neuroscientist Vilayanur S. Ramachandran, surgical pioneer Roy Calne, psychiatrist David Healy, philosopher David Pearce, and the Nobel laureate Arvid Carlsson. Mehar Manku became the editor of Medical Hypotheses after Charlton was fired in 2010. Medical Hypotheses was initially published by Eden Press. Elsevier has been its publisher since 2002. Abstracting and indexing The journal is abstracted and indexed in the Science Citation Index, Index Medicus/MEDLINE/PubMed, BIOSIS Previews, Chemical Abstracts, Elsevier BIOBASE/Current Awareness in Biological Sciences, Current Contents/Clinical Medicine, Current Contents/Life Sciences, and EMBASE/Excerpta Medica. Research The most widely cited article from Medical Hypotheses was published in 1991 by Ronald S. Smith in which he proposed the macrophage theory of depression as an alternative to the monoamine theory of depression. Other famous articles featured in the journal include the proposal from Jarl Flensmark of Malmö, Sweden, that schizophrenia may be caused by wearing heeled shoes, and an article from Svetlana Komarova of McGill University positing that facial hair may play a role in preventing the development of cancer. In what psychiatrist and The Guardian columnist Ben Goldacre called an "almost surreally crass paper", two Medical Hypotheses authors posited "mongoloid" as an accurate term for people with Down syndrome because those with Down syndrome share characteristics with people of Asian origin, including a reported interest in crafts, sitting with crossed legs and eating foods containing monosodium glutamate (MSG). Correspondence items have presented masturbation as a treatment for nasal congestion. Science reported that a 2009 paper by Georg Steinhauser on navel lint "became an instant classic". In 2007, journalist Roger Dobson published a book in which he collected and described 100 Medical Hypotheses articles called Death Can Be Cured. Peer review debate Horrobin began the journal in response to what he viewed as the limitations of peer review. He wrote, "The primary criteria for acceptance are very different from the usual journals. In essence what I look for are answers to two questions only: Is there some biological plausibility to what the author is saying? Is the paper readable? We are NOT looking at whether or not the paper is true but merely at whether it is interesting." According to physiologist John Stein, Horrobin believed from his days as an undergraduate that peer review encourages adherence to currently accepted ideas at the expense of innovation. Also neuroscientist Vilayanur Ramachandran, who is on the journal's editorial