Agnes Macdonald may refer to: Agnes Macdonald, 1st Baroness Macdonald of Earnscliffe, second wife of Sir John A. Macdonald Agnes Syme Macdonald, Scottish suffragette Agnes Gertrude VanKoughnet, Canadian socialite and second wife of Hugh John Macdonald Agnes MacDonald, one of the MacDonald sisters, Scottish women notable for their marriages to well-known men See also Agnes McDonald, New Zealand nurse, postmistress and teacher