test for Primary Biliary Cirrhosis and later showed that it was an autoimmune disease. She also demonstrated the efficacy of corticosteroid therapy for autoimmune hepatitis. She also recognised the link between hepatitis B and hepatocellular carcinoma. In 2006, the Sheila Sherlock Prizes were founded with a donation from her husband, Dr Geraint James. The two prizes are awarded to the highest achieving medical students at the UCL Medical School. In March 2008, on the 90th anniversary of her birth, the liver unit which she had founded at the Royal Free Hospital, was renamed the Sheila Sherlock Liver Centre in her memory. Professor Priscilla Kincaid-Smith, nephrologist said of her:—{{blockquote|text="She was a superb clinician; we all used to go to Sheila's round. She'd be as rude as anything to you on the round – really pick you out and say, 'That's absolute rubbish,' and walk on to the next patient. But she was tremendous, a really wonderful clinician."}} Criticism In Human guinea pigs Dr. Maurice Henry Pappworth criticises Prof. Sherlock. He explains he felt she was conducting experiments on patients which she knew to be harmful an example give is that she wrote 'It is dangerous to give amino-acids such as methionine, which are toxic, to patients with liver disease. ... Patients in impending coma are extremely sensitive to sedatives. If the patient is uncontrollable half the usual dose of pentobarbital may be given: morphia is absolutely contraindicated, Drugs known to induce hepatic coma such as ammonium sals, ammonium-exchange resins, methionine, urea and diamond are disallowed''' in the British Medical Bulletin in 1957 but then went on to conduct an experiment in which those with liver disease morphine. References Bibliography External links Watch a video oral history interview with Dame Sheila Sherlock – recorded by Oxford Brookes University in partnership with the Royal College of Physicians as part of the Medical Sciences Video Archive. 1918 births 2001 deaths Medical doctors from London Alumni of the University of Edinburgh Dames Commander of the Order of the British Empire Deaths from pulmonary fibrosis British hepatologists Fellows of the Royal College of Physicians Female Fellows of the Royal Society British women medical doctors People educated at Folkestone School for Girls Fellows of the Royal Society 20th-century British women scientists Physicians of the Royal Free Hospital 20th-century women physicians Fellows of the Royal College of Physicians of Ireland