missed the second leg of the UEFA Europa League round-of-32 tie against FC Porto and the Bundesliga clash with Bayern Munich due to an adductor injury, as tests confirmed that the 27-year-old would be out for up to three weeks. The Greek centre back picked up the injury during Dortmund's 1–0 win against Bayer Leverkusen and was replaced 13 minutes from time at the BayArena. On 21 May 2016, Papastathopoulos featured in his third DFB-Pokal final in a row, putting in a tremendous performance despite a missed penalty, but he did not succeed in winning the DFB-Pokal for first time in his career. He started the 2016–17 season as the undisputed leader in BVB defence. On 15 September 2016, he netted the second goal in an away crashing 6–0 against Legia Warsaw on a Group Champions League match. On 4 January 2017 the German magazine "kicker" listed the Greek international as one of the best players in the German Bundesliga. The magazine paid a tribute to the best players currently playing in the German Bundesliga, separating them out into different categories. In the first category (World Class) no defenders were listed, however, Papastathopoulos was one of three defenders listed in the second category, International Class. The other two defenders included Mats Hummels of Bayern Munich and Jonathan Tah of Bayer Leverkusen. On 8 February 2017, in a DFB Pokal home win on penalties' game against Hertha Berlin, Papastathopoulos' two quickfire (in a minute) bookings for dissent saw Dortmund finish extra time with 10 men before Fabian Lustenberger, Vladimír Darida and Salomon Kalou all erred from the spot, rendering Christian Pulisic's miss irrelevant. On 25 February 2017, Dortmund made three changes from last weekend's 3–0 win over VfL Wolfsburg and it was two of those, Papastathopoulos and Raphaël Guerreiro, who combined to open the scoring in the 13th minute in a 3–0 away win against SC Freiburg. Papastathopoulos looked to be offside as Guerreiro swung in a free-kick from the right, which the Greece defender met with a header planted inside the right-hand post. On 16 April 2017, Papastathopoulos was the one who had a quick reaction to an Eintracht Frankfurt equalising, by scoring a goal after Sven Bender's assist giving a lead to the score in his team in a final 3–1 home win. On 26 April 2017, helped Borussia Dortmund to a 3–2 win over Bayern Munich and their