total (15 in the alpha subunit and 13 in the beta subunit) and 15 very short (no more than 4 residues) beta sheets. Functional RabGGTase binds three metal ions as ligands: two calcium ions (Ca2+) and a zinc ion (Zn2+), all of which interact with the beta subunit. See also Farnesyltransferase Geranylgeranyltransferase type 1 – also referred to as Geranylgeranyltranferase 1 or just Geranylgeranyltranferase Prenylation References Coxon, Fraser P., Frank H. Ebetino, Emilie H. Mules, Miguel C. Seabra, Charles E. McKenna and Michael J. Rogers. Phosphonocarboxylate inhibitors of Rabnext term geranylgeranyl transferase disrupt the prenylation and membrane localization of previous termRabnext term proteins in osteoclasts in vitro and in vivo. Bone Vol. 37, Iss. 3. Sept. 2005, p. 349-358. Chinpaisal, Chatchai, Chih-Hao Lee and Li-Na Wei. Studies of the mouse Rabnext term geranylgeranyl transferase β subunit: gene structure, expression and regulation . Gene Vol. 184, Iss. 2 Jan. 1997, p. 237-43. Sinnott, M. (Ed.), Comprehensive Biological Catalysis. A Mechanistic Reference, vol. 1, Academic Press, San Diego, CA, 1998, p. 31-118. External links EC 2.5.1