The Breed is a 2006 natural horror film that is directed by Nicholas Mastandrea. Having marked Mastandrea's directorial debut, the film features two brothers and their friends who travel to an island cabin the brothers inherited from their recently deceased uncle for a relaxing weekend getaway. However, the group is besieged by ravenous genetically enhanced dogs bred to kill via an abandoned training facility on the Island. Plot A couple on a small sailboat find a small island and begin to look around. The woman wanders off while the man ties up the boat. She stumbles across a fence and a small compound, but no one seems to be around. She is then attacked by unknown creatures. The man at the boat is startled by her screams. Sometime later, a seaplane heads to what appears to be the same island. Matt (Lively) and John (Hudson) are two brothers who are heading to the island for a week of fun and relaxation. The island was owned by their uncle, who built a cabin on it. He recently died, and the island is otherwise uninhabited. The brothers are joined by three friends, Nicki (Rodriguez), Sara (Manning) and Noah (Harper). Upon landing, they moor the seaplane at a dock near the cabin. Soon after they arrive, a puppy shows up. The friends take him in to the cabin. Noah goes into the kitchen to get a drink. The puppy follows him in. The puppy then mysteriously growls at him and runs off. Sara and John then follow him out. They are ambushed by an older vicious dog and Sara is bitten by it. The pair manage to get back to the cabin. The following morning, the men are in the forest. They bump into the man who came to the island at the beginning of the movie. He is bloody and warns them about the dogs. A pack of dogs attack and eat him. The men run back to the cabin and tell the women to come inside. A dog attacks Nicki and John shoots an arrow to save her, wanting to kill a dog, but accidentally impales one through of Nicki's shin instead. They are soon under siege by more vicious dogs, one of which they impale with a hot-poker. The friends decide they must leave the island, but dogs have surrounded the plane. As they have no other way off the