with its side chain-demethylated metabolite norbutriptyline being a secondary amine. Other tertiary amine TCAs include amitriptyline, imipramine, clomipramine, dosulepin (dothiepin), doxepin, and trimipramine. The chemical name of butriptyline is 3-(10,11-dihydro-5H-dibenzo[a,d]cycloheptene-5-yl)-N,N,2-trimethylpropan-1-amine and its free base form has a chemical formula of C21H27N with a molecular weight of 293.446 g/mol. The drug has been used commercially both as the free base and as the hydrochloride salt. The CAS Registry Number of the free base is 15686-37-0 and of the hydrochloride is 5585-73-9. History Butriptyline was developed by Wyeth and introduced in the United Kingdom in either 1974 or 1975. Society and culture Generic names Butriptyline is the English and French generic name of the drug and its , , and , while butriptyline hydrochloride is its and . Its generic name in Latin is butriptylinum, in German is butriptylin, and in Spanish is butriptylina. Brand names Butriptyline has been marketed under the brand names Evadene, Evadyne, Evasidol, and Centrolese. Availability Butriptyline has been marketed in Europe, including in the United Kingdom, Belgium, Luxembourg, Austria, and Italy. References Abandoned drugs Alpha-1 blockers Dimethylamino compounds Dibenzocycloheptenes H1 receptor antagonists Muscarinic antagonists Serotonin receptor antagonists Tricyclic antidepressants