hereditary spastic paraplegia, as is AP-4. AP-1 is linked to MEDNIK syndrome. AP-3 is linked to Hermansky–Pudlak syndrome. COPI is linked to an autoimmune disease. COPII is linked to cranio-lenticulo-sutural dysplasia. One of the GGA proteins may be involved in Alzheimer's disease. Gallery See also Exomer List of adaptins SNAREs Molecular evolution Biogenesis of lysosome-related organelles complex 1 Notes References External links A collage of electron micrographs showing COPI, COPII and clathrin vesicles structure of COPI coat from this publication, free with free registration Video description of the COPII disease CLSD iBiology videos by Kai Simons about lipids, lipid rafts and cellular trafficking Part 1: The role of lipids in organizing the cellular traffic. Part 2: Lipid rafts as a membrane organizing principle Part 3: Biogenesis of glycolipid-rich apical membranes Cell biology Cell anatomy Organelles Protein complexes Protein families Molecular evolution Vesicular transport proteins