Somatostatin receptors are receptors for the ligand somatostatin, a small neuropeptide associated with neural signaling, particularly in the post-synaptic response to NMDA receptor co-stimulation/activation. Somatostatin is encoded by a CRE and is very susceptible to gene promoter region activation by transcription factor CREB. There are five known somatostatin receptors: SST1 () SST2 () SST3 () SST4 () SST5 () All are G protein-coupled seven transmembrane receptors. References External links G protein-coupled receptors