surgery to save her and baby Sofia's life. It was also used when Derek died and Meredith stood at his bedside. The song also featured prominently in the season five Scrubs episode "My Lunch", and was used as the song of choice for the 'best bits' of season 8 of Big Brother UK. "How to Save a Life" was also featured in One Tree Hill. Music videos The original music video, which premiered on VH1 on September 12, 2006, featured the recurring themes of light and stopped time. This music video shows the scene of a car crash and all of its presumed victims in pause. There is a recurring light throughout the video shining brightly in the dark woods that the video takes place in. Scenes of the band playing in a dark warehouse are intercut with the story going on outside. This version of the video was placed at No. 21 of the year by VH1's "Top 40 Videos of 2006". Another version of the music video juxtaposes scenes from Grey's Anatomy to scenes of the original music video. However, all the scenes of the presumed car crash victims are excluded and only scenes of the Fray playing in a warehouse are shown. A third music video, directed by Mark Pellington, was released for the song on December 6, 2006. The video features various adolescents, most of which seem to be between 12 and 18 in age, all who appear to be depressed and suicidal, or possibly mourning the loss of a loved one. All of these children have lost a significant loved one prior to the video, and many of them cry and scream in the video, all against a white background. Scenes of the band playing the song against this same white background are also shown throughout the video. Many numbered steps are shown alongside them, such as "Remember", "Cry", or "Let It Go". The video ends with each child finding a catharsis and making peace with themselves or others. This version of the video debuted on MTV's Total Request Live (TRL) at No. 9, and went on to top the countdown at No. 1 on December 21, 2006, becoming the band's first TRL No. 1, and also becoming the last No. 1 video on TRL for 2006. Track listings CD 1 "How to Save a Life" (single mix) - 4:00 "She Is" – Acoustic from