Govind and his team try to save him but is too late and they watch helplessly as he dies. Govind, saddened by the event, quarantines the lab room and fills it with a concentrated salt solution. After learning the original virus's lethal potential the hard way, Govind refuses to hand over the main single vial containing the virus due to fear of misuse. However his boss and senior scientist, Dr. Sethu has a malicious plan in mind - to sell it to a terrorist nation. Realizing this, Govind sneaks the vial out of the lab and is pursued by the security guard and the officials. Govind flees to his friend and coworker Suresh's house for refuge, who secretly betrays him. A helicopter housing a rogue CIA agent Christian Fletcher, arrives in the middle of Govind's and Suresh's house. Fletcher fast-ropes down to Suresh's apartment with a crossbow, shoots Suresh and attempts to seize the vial. Govind flees away while Yukha Narahazi, Suresh's wife and an Aikido champion, fights Fletcher and protects Govind. Govind manages to jump into another apartment's window and escapes the building before the apartment is bombed by Fletcher. The virus is inadvertently shipped to India by Govind's friend Sairam aboard a passenger aircraft, safely in Govind's hands. Govind secretly boards the aircraft carrying the virus and changes its location. Govind later learns that the package containing the vial is being sent to Krishnaveni. In Japan, a skilled Martial arts teacher Shingen Narahazi who is Yuka Narahazi's elder brother gets informed of his sister's murder and sets out to finish the culprit. After arriving in India, Govind is questioned by Balram Naidu, a quirky RAW operative, who immediately dislikes Govind. Govind unsuccessfully tries to explain the series of incidents, but Naidu believes him to be a member of a gang. Meanwhile, Fletcher, who has married an Indian assassin named Jasmine, arrives in Chennai. After marrying her and using her as a translator, Fletcher threatens Govind and a police officer Bharat and takes them away in a jeep, after killing two Black Cats at the airport for a clean exit from pursuing Indian authorities. The arrival of the famous pop singer Avatar Singh makes their escape easy. After exiting the city, Govind escapes from Fletcher with the help of the policeman and reaches Chidambaram. Fletcher follows him along with Jasmine, after hiring a cab, After Govind attempts to persuade