luminal surface of the inner placenta compartment. It was obvious that the Kurloff cell must have a role during pregnancy in the guinea-pig because of a significant increase in the number of these cells in the blood and tissues. The inclusion material has been proved to prevent immunological damage to target cells when purified. Studies were done on the effect of extracted inclusion body material in purified form, on inflammatory cells in vitro. The results showed marked toxic effects on macrophages with first clumping follow by cell death. The evidence suggests that Kurloff cells may play a part in preventing immunological damage to the trophoblast by maternal defensive cells. See also Resistance to cancer in naked mole rats Russell bodies References Blood cells Cavies