The ligamenta flava (singular, ligamentum flavum, Latin for yellow ligament) are a series of ligaments that connect the ventral parts of the laminae of adjacent vertebrae. They help to preserve upright posture, preventing hyperflexion, and ensuring that the vertebral column straightens after flexion. Hypertrophy can cause spinal stenosis. Structure Each ligamentum flavum connects the laminae two adjacent vertebrae. They begin with the junction of the axis and third cervical vertebra, continuing down to the junction of the fifth lumbar vertebra and the sacrum. They are best seen from the interior of the vertebral canal. when looked at from the outer surface they appear short, being overlapped by the lamina of the vertebral arch. Each ligament consists of two lateral portions which commence one on either side of the roots of the articular processes, and extend backward to the point where the laminae meet to form the spinous process; the posterior margins of the two portions are in contact and to a certain extent united, slight intervals being left for the passage of small vessels. Each consists of yellow elastic tissue, the fibers of which, almost perpendicular in direction, are attached to the anterior surface of the lamina above, some distance from its inferior margin, and to the posterior surface and upper margin of the lamina below. In the neck region the ligaments are thin, but broad and long; they are thicker in the thoracic region, and thickest in the lumbar region. They are thinnest between the atlas bone (C1) and the axis bone (C2), and may not be present in some people. They become longer inferiorly in the cervical spine, as the distance between adjacent laminae increases. Function The marked elasticity of the ligamenta flava serves to preserve upright posture, and to assist the vertebral column in resuming it after flexion. The elastin, fairly unique to the ligamenta flava among other ligaments, prevents buckling of the ligament into the spinal canal during extension, which would cause spinal cord compression. Clinical significance Because these ligaments lie in the posterior part of the vertebral canal, their hypertrophy can cause spinal stenosis, particularly in patients with diffuse idiopathic skeletal hyperostosis. The ligamenta flava may also become fatty or calcify during ageing. These cause degeneration of elastin. Some studies indicate that the hypertrophy of these ligaments may be linked to a fibrotic process associated with increased collagen VI, which could represent an adaptive and