Erinsborough High. Alex is diagnosed with Lymphoma and he asks Susan to marry him; she accepts. Alex's condition deteriorates and they decide to marry right away. The marriage is witnessed by Karl, Rachel, Zeke, and Alex's older daughter, Katya (Dichen Lachman). Alex passes away shortly after. Susan begins to fall for Karl again and she declares her love for him. They get back together in secret, but Rachel and Zeke find out the truth and believe that Susan did not love their father. They later give Karl and Susan their blessings. While Susan and Karl are on holiday in London, Karl proposes for a third time. Susan immediately accepts and they remarry on a boat on the Thames. The ceremony is interrupted when Izzy goes into labour and Karl delivers her daughter, Holly (Chaya Broadmore). Susan discovers that Karl is Holly's father and she tells him when they get back home. During a period of ill health, Susan hits Bridget Parker (Eloise Mignon) with her car after passing out. Susan is unaware that she has struck Bridget and she leaves the scene. When she realises that she is responsible, Susan confesses and it causes a bitter feud between the Kennedys and the Parkers. However, during Susan's trial, Bridget remembers falling into the path of the car and that the collision was unavoidable. Soon afterwards, following a series of incorrect diagnoses, Susan is diagnosed with multiple sclerosis. Susan is shocked and scared, and Karl and Libby try to help her. Susan collapses at Toadie and Steph's wedding rehearsal and she goes to a multiple sclerosis retreat for professional help. Susan takes sick leave from the school and becomes a journalist for the Erinsborough News. After Libby is told she cannot have any more children, she and Dan decide to try surrogacy. Susan offers to be their surrogate, despite Karl's objections. Paul Robinson finds out about the surrogacy and writes a newspaper article about it, without knowing the identity of the family involved. When he finds out that Susan is the surrogate, he makes it public. The family face abuse and the hospital board decide to end the programme. Libby and Dan protest against the decision and Susan tries blackmailing a senior board member. The board change their minds and Susan becomes pregnant. Dan finds it hard to relate to Susan and begins to question her part in his and Libby's lives.