Emotional isolation is a state of isolation where one may have a well-functioning social network but still feels emotionally separated from others. Population-based research indicates that one in five middle-aged and elderly men (50–80 years) in Sweden are emotionally isolated (defined as having no one in whom one can confide). Of those who do have someone in whom they can confide, eight out of ten confide only in their partner. People who have no one in whom they can confide are less likely to feel alert and strong, calm, energetic and happy. Instead, they are more likely to feel depressed, sad, tired and worn out. Many people suffering from this kind of isolation have strong social networks, but lack a significant bond with their friends. While they can build superficial friendships, they are often not able to confide in many people. People who are isolated emotionally usually feel lonely and unable to relate to others. In relationships Emotional isolation can occur as a result of social isolation, or when a person lacks any close confidant or intimate partner. Even though social relationships are necessary for emotional well-being, they can trigger negative feelings and thoughts and emotional isolation can act as a defense mechanism to protect a person from emotional distress. When people are emotionally isolated, they keep their feelings completely to themselves, are unable to receive emotional support from others, feel "shut down" or numb, and are reluctant or unwilling to communicate with others, except perhaps for the most superficial matters. Emotional isolation can occur within an intimate relationship, particularly as a result of infidelity, abuse, or other trust issues. One or both partners may feel alone within the relationship, rather than supported and fulfilled. Identifying the source of the distress and working with a therapist to improve communication and rebuild trust can help couples re-establish their emotional bond. Effects on the mind Cacioppo and his team have found that the brains of lonely people react differently than those with strong social networks. The University of Chicago researchers showed lonely and non-lonely subjects photographs of people in both pleasant settings and unpleasant settings. When viewing the pleasant pictures, non-lonely subjects showed much more activity in a section of the brain known as the ventral striatum than the lonely subjects. The ventral striatum plays an important role in learning. It is also part of the brain's reward center, and can be