back to the Premier League for the 2010–11 season, Guthrie took part in Newcastle's pre-season fixtures, playing in the 2–2 draw with PSV on the left wing, and in central midfield alongside Joey Barton in a 2–1 defeat to Rangers. He missed the opening fixtures of the Premier League season against Manchester United, Aston Villa, Wolverhampton Wanderers and Blackpool with a knee injury . He returned to contention in October after making a string of reserve team games. He returned to play against Wigan in a 2–2 draw, playing on the right wing. He was dropped for the next game, however, after an unimpressive display. Throughout the season, Guthrie was largely an out-of-favour player with Newcastle after the signing of Cheick Tioté in August 2010. The consistent form of Joey Barton and Kevin Nolan also kept the 24-year-old on the bench throughout much of the season, where he only registered one assist. A knee injury suffered in pre-season kept Guthrie out of the first few months of the 2011–12 Premier League season and made his return in the 4–3 League Cup defeat to Blackburn Rovers, scoring a long-range goal in the process. Due to an injury to Tioté, Guthrie started against Stoke City and Everton. On 21 January 2012, he scored a superb long-range goal against Fulham at Craven Cottage to give Newcastle a 1–0 lead, a game they would eventually go on to lose 5–2. Guthrie was released by Newcastle on 1 June 2012. Reading On 29 June 2012, Guthrie signed a three-year contract at newly promoted Premier League club Reading on a free transfer. He scored his first goal for Reading in only his second game, away at Chelsea, after goalkeeper Petr Čech spilled his free kick into the net. In October, it was reported by local and national newspapers that Guthrie and Reading manager Brian McDermott had fallen out after he was dropped from the team for the 3–3 draw with Fulham. The claims were denied by both the player and manager. On 11 December, McDermott revealed that Guthrie had refused to travel with the team for the away game against Sunderland, as his "head was not in the right place". He was fined two weeks wages and the following day issued a full apology stating that he had "loved his time at the club" and would do everything in his power to regain a first-team spot.