the most iconic character of the series. She is the first nurse Ryuji meets and the first who genuinely welcomes him as a friend and superior. When her love for an inpatient boxer, Naoya Ohkawa, is discovered, Ryuji learns of her match fixing and uses it as blackmail. Like the nurses to come, in spite of the abhorrent treatment she receives, Ren develops Stockholm syndrome and becomes emotionally attached to her abuser. Ren is distinguishable by her incredibly long hair, of which is usually tied into a ponytail. It is later revealed that she is pregnant. She is the one who kills Ryuji after he gained back his consciousness. After being arrested she admits that she loves him. In Night Shift Nurses Kranke, she marries Ryuji, lives with him in the countryside, and becomes a "good" wife. : Remi Shinjyo is a twenty-seven-year-old senior nurse of the hospital maternity ward. As a headstrong superior, Remi is outwardly proud, fastidious and authoritative, especially to Ryuji. Although it is not mentioned until later, Remi is responsible for an act of malpractice that resulted in the death of a patient. Ryuji takes advantage of Remi's malpractice and subjects her to inhumane experiments. Like Ren, Remi falls for Ryuji and shows huge interest of wanting to be experimented by Ryuji again. Amongst all the nurses, she is one of the few nurses in the series that is not a virgin. : Shy and quiet, Ako Fujisawa is a twenty-three-year-old pharmacist. The daughter of a wealthy family, she is falsely accused of stealing drugs from her department and this is used as the basis for her series of abuse. In much the same fashion as Ren and Remi, Ako develops delusional, obedient feelings for Ryuji. Owing to one of the elements of the show, Ako becomes a coprophile. : Hikaru Kodama is a twenty-one-year-old amateur nurse, newly employed and specializing in pediatrics. As her department suggests, Hikaru absolutely loves children and like them, is energetic. She is the fourth and final nurse to be subjected to Ryuji and by far endures the most inhumane practices in the first phase of the series. It is later revealed that most of the group has to endure the same thing as her. Hikaru is noted for her pigtails and loose socks. She has an adoptive sister, Ai, hospitalized for heart problems. She later admits to have fallen for