Night Shift Nurses is the North American localization of , a Japanese OVA series adapted by Discovery from the visual novel of the same name. It was formerly licensed by Anime 18, and now by Critical Mass Video. The series is particularly notorious for its explicit depictions of rape, necrophilia, sadomasochism, and paraphilia. Synopsis Setting Night Shift Nurses, as was originally written for the game, takes place in an undisclosed area of Japan, mainly at the fictional St. Juliana Hospital. A majority of the game is portrayed on campus with minor visits to the character's residences and surrounding towns. Plot Yakin Byōto 1: Ryuji Hirasaka is an unemployed, middle-aged Japanese gynaecologist, single, independent, and living on his own. One evening, he receives an email from the fictional St. Juliana Hospital, a local institution, offering him a temporary job opportunity. He contently accepts, scheduling to meet with the president the following day. That afternoon, semi-formal and with a portfolio, Ryuji commutes to the hospital. After an acquaintance with Ren Nanase, a nurse who escorts him to the president, he is frightened to discover his potential employer is a woman he had brutally raped in the past, Narumi Jinguji. In spite of the excruciating atmosphere, however, Narumi explains her wish to develop a department in the hospital that caters to the sexual interests of patients; in need of his expertise to oversee the operation. Overwhelmed with lewd excitement, Ryuji agrees. Yakin Byōto 2: A young elite doctor Souichiro Kuwabara couldn't forget his feelings towards Ren Nanase, whom he had fallen in love with back in his training days. He's been switching occupations at different hospitals one after another, to go look for her, and finally he meets her again at the Sei-Katorea General Hospital. However, her attitude was remote and sadly enough his love couldn't be fulfilled. To make things worse and more complicated, he finds a stack of photographs depicting Ren being molested. Ren had been turned into a lewd woman by Hirasaka when she was still working at St. Julianna. He was very disappointed after what he had witnessed to the point where he ends up losing his mind and going insane-(both mentally and sexually). Yakin Byōto 3: In a rural village, Yotsuya Jiro, a young novelist was lying in front of a hospital after falling off his bike. He was seriously injured with a broken leg, and when he