MD 4 immediately intersects MD 262 (Lower Marlboro Road) at another directional crossover intersection; the portion of MD 262 east of MD 4 has a right-in/right-out intersection with northbound MD 4. The highway crosses Chew Creek and Hall Creek on either side of Chaneyville, then passes through the town center of Dunkirk. Immediately south of the Calvert–Anne Arundel county line at Lyons Creek, MD 4 has a partial trumpet interchange with MD 260 (Chesapeake Beach Road); there is no access from MD 260 to southbound MD 4. The highway continues north paralleled by service roads briefly on the east (Fishers Station Road) and then on the west (MD 4 Service Road); both are segments of MD 980. A park and ride lot serving MTA Maryland commuter buses is located east of MD 4 north of the Lower Pindell Road intersection, with access from MD 980B service road. The divided highway and service road run north to Bristol, where the divided highway has a diamond interchange with MD 258 (Bay Front Road), which leads to MD 259 (Greenock Road) and MD 794 (Southern Maryland Boulevard). MD 4 continues northwest as Stephanie Roper Highway, with MD 794 (Southern Maryland Boulevard) paralleling on the northbound side. The southbound side is paralleled by another segment of MD 980 (MD 4 Service Road); there are ramps and right-in/right-out intersections with the parallel service roads on either side of Galloway Creek east of Jug Bay Wetlands Sanctuary. MD 4 curves west at its diamond interchange with MD 408 (Mt. Zion–Marlboro Road) at Waysons Corner. The highway crosses the Patuxent River into Prince George's County on Hills Bridge and has a northbound ramp to Marlboro Pike and a southbound ramp from Green Landing Road, which is unsigned MD 726. MD 4 has a cloverleaf interchange with U.S. Route 301 (Robert Crain Highway) and crosses over CSX's Pope's Creek Subdivision rail line. The freeway continues to the south of the town of Upper Marlboro, which is accessed via MD 4's diamond interchange with MD 717 (Water Street), which heads north toward the Prince George's County courthouse and county offices in the center of town and the Prince George's Equestrian Center and Show Place Arena to the south. MD 4 continues west as Pennsylvania Avenue and crosses the Western Branch of the Patuxent River just west of MD 717. West of Upper Marlboro, the freeway has a half-diamond interchange