Too (1981) and Caryl Churchill's Top Girls (1982) and Serious Money (1987). She also starred in the Top Girls Off-Broadway production in 1983. For the RSC, she starred in As You Like It (1985) and Les Liaisons Dangereuses (1985–86). She made her film debut in 1985s Dance with a Stranger directed by Mike Newell, and went on to appear in Sammy and Rosie Get Laid (1987) directed by Stephen Frears, and High Season (1987). Back on the stage, she starred in The Cherry Orchard at the Aldwych Theatre in 1989, directed by Sam Mendes, and in Three Sisters at the Royal Court in 1990. In 1994, Manville starred in the first series of the BBC sitcom Ain't Misbehavin'. For her work in the 2000 miniseries Other People's Children, and the 2002 TV film Bodily Harm, she received nominations for Best Female Actor at the Royal Television Society Awards. Her extensive television credits include prominent roles in the dramas Holding On (1997), Real Women (1998–99), The Cazalets (2001), North & South (2004) and Cranford (2007). She also starred in Cards on the Table, a 2006 feature-length episode of Agatha Christie's Poirot. Since 2005, Manville has starred in several National Theatre productions, including His Dark Materials (2005), The Alchemist (2006) and Her Naked Skin (2008). She also starred in The Old Vic productions of All About My Mother (2007) and Six Degrees of Separation (2010). In 2009, she played Margaret Thatcher in the Channel 4 drama The Queen. Manville has appeared in numerous Mike Leigh films throughout her career, including High Hopes (1988), Secrets & Lies (1996), Topsy-Turvy (1999), Vera Drake (2004) and Mr. Turner (2014). Her most notable Mike Leigh films are All or Nothing in 2002 and Another Year in 2010. For both, she won the London Film Critics Circle Award for British Actress of the Year. For Another Year, she also won the National Board of Review Award for Best Actress, and was nominated for the British Independent Film Award for Best Supporting Actress and the European Film Award for Best Actress, as well as the Chicago Film Critics Award for Best Actress. She also won Best Supporting Actress from the San Diego Film Critics Society. On 18 January 2011, she received a BAFTA nomination in the Best Supporting Actress category. On 7 February 2011, former Charlie's Angels stars Jaclyn Smith and Cheryl Ladd presented the Best Actress Award