treatment of glioblastoma multiforme and is considered as a possible therapeutic option for glioma. Antiviral effect Seliciclib is also a possible antiviral agent. It causes the death of cells infected with HIV and preventing the replication of herpes simplex virus. Ovum production Seliciclib has been shown to cause parthenogenetic egg activation. However it does create abnormal second polar bodies and therefore possible aneuploid zygotes. Egg activation usually involves calcium oscillations however this does not happen with seliciclib. Seciclib causes egg activation by inhibiting protein kinases which results in the inactivation of the maturation promoting factor (MPF). Renal hypertrophy Seliciclib reduces renal hypertrophy by 45% after 5/6 nephrectomy. Side effects Causes severe side effects that can not be tolerated on daily bases. Side effects include hypokalemia and elevation of liver enzymes. Due to these side effects Seliciclib has not been approved by the USFDA. References Primary alcohols Purines Protein kinase inhibitors Experimental drugs Isopropyl compounds