successes. In Battle of Chaul in 1508, Lourenço de Almeida was defeated and lost his life; but in the following year this defeat was avenged by a terrible defeat of the Egyptian fleet at the Battle of Diu in which the Port city of Diu was wrested from the Gujarat Sultanate of India by Francisco de Almeida. Some years after, Afonso de Albuquerque tried to take Aden, while the Egyptian troops suffered disaster in Yemen. Al-Ashraf Qansuh al-Ghuri now fitted out a new fleet to punish the enemy and protect the Indian trade; but before its results were known, Egypt had lost her sovereignty, and the Red Sea with Mecca and all its Arabian interests had passed into Ottoman hands. Ottoman-Safavid intrusions Ottoman Sultan Bayezid II was still engaged in Europe when there suddenly in 1501 appeared a new ground of hostility with Egypt. It arose out of the relations of the two kingdoms with the Safavid dynasty in Persia. Shah Ismail I of Persia was a Shia Muslim who had embarked on a war with the Sunni Ottoman Sultanate over the Caucasus and religious differences. Many Sufi sects had been arrested or exiled by Sultan Bayezid II as dangerous to his rule; and Shah Ismail I's request, that instead they should be allowed free transit into Europe across the Bosporus, was rejected. Upon this, Shah Ismail I sent an Embassy to the Venetians via Syria inviting them to join his arms and recover the territory taken from them by the Porte. Sultan Bayezid II, angry with the Mamluk Sultan Al-Ashraf Qansuh al-Ghuri, complained bitterly that this Embassy had been suffered to pass through Syria. To appease him, Al-Ashraf Qansuh al-Ghuri placed in confinement the Venetian merchants then in Syria and Egypt. And although, fearing reprisals from Venice, he after a year released them, yet the relations between Egypt and the Porte remained peaceful for a time. On the succession, however, of Selim I to the throne of Ottoman Sultanate, things took a very different turn. Not only had the attitude of Shah Ismail I become more threatening, but Sultan Selim I himself was more of the warrior than his father. Selim I set out against him, and the Battle of Chaldiran was fought near Tabriz on 23 August 1514. The fanaticism of the Sufis, which led even to their women joining in the combat, failed against the cavalry and