This is consistent with the SOA approach popular in that era. This approach relies on mappings between the mediated schema and the schema of original sources, and translating a query into decomposed queries to match the schema of the original databases. Such mappings can be specified in two ways: as a mapping from entities in the mediated schema to entities in the original sources (the "Global-as-View" (GAV) approach), or as a mapping from entities in the original sources to the mediated schema (the "Local-as-View" (LAV) approach). The latter approach requires more sophisticated inferences to resolve a query on the mediated schema, but makes it easier to add new data sources to a (stable) mediated schema. some of the work in data integration research concerns the semantic integration problem. This problem addresses not the structuring of the architecture of the integration, but how to resolve semantic conflicts between heterogeneous data sources. For example, if two companies merge their databases, certain concepts and definitions in their respective schemas like "earnings" inevitably have different meanings. In one database it may mean profits in dollars (a floating-point number), while in the other it might represent the number of sales (an integer). A common strategy for the resolution of such problems involves the use of ontologies which explicitly define schema terms and thus help to resolve semantic conflicts. This approach represents ontology-based data integration. On the other hand, the problem of combining research results from different bioinformatics repositories requires bench-marking of the similarities, computed from different data sources, on a single criterion such as positive predictive value. This enables the data sources to be directly comparable and can be integrated even when the natures of experiments are distinct. it was determined that current data modeling methods were imparting data isolation into every data architecture in the form of islands of disparate data and information silos. This data isolation is an unintended artifact of the data modeling methodology that results in the development of disparate data models. Disparate data models, when instantiated as databases, form disparate databases. Enhanced data model methodologies have been developed to eliminate the data isolation artifact and to promote the development of integrated data models. One enhanced data modeling method recasts data models by augmenting them with structural metadata in the form of standardized data entities. As a result of recasting multiple data models, the set of recast data models will now