in MRI that promises to shape its future. Real-time MRI will again broaden the diagnostic potential of MRI by adding completely new, hitherto impossible scientific and clinical applications as well as by simplifying and shortening existing procedures. More recently, the algorithm for regularized nonlinear inversion (NLINV) has been extended to allow for model-based reconstructions of quantitative parametric maps directly from suitable sets of MRI raw data. Relevant physical or physiological parameters are, for example, T1 relaxation times of water protons in various body tissues and the velocities of blood flow or cerebrospinal fluid (CSF) flow. These novel approaches include a corresponding signal model into the MRI signal equation and therefore always pose a nonlinear inverse reconstruction problem. However, as already demonstrated for real-time MRI, the computational demand is met by a user-invisible GPU-based bypass computer which may be retrofitted to an existing MRI system. The results offer fundamental advantages in comparison to conventional mapping methods which are based on serial image reconstructions followed by pixelwise fitting. Publications The list of Frahm's publications exhibits more than 550 entries comprising patents, scientific articles, review articles, and book chapters (as of January 2023), see . His Hirsch index is 104. Awards 1989 European MRI Award, German Roentgen Society 1990 European Magnetic Resonance Award, European Workshop on NMR in Medicine 1991 Gold Medal Award, International Society of Magnetic Resonance in Medicine 1992 Hans-Meyer-Award, Roentgen Society of Lower Saxony 1993 Karl-Heinz-Beckurts-Award, Beckurts-Foundation 1996 Niedersachsenpreis, President of the State of Lower Saxony 2005 Research Award of the Sobek-Foundation 2006 Biomedizinische NMR Forschungs GmbH 2013 Science Award (Stifterverband Award) of the Donors' Association for the Promotion of the Sciences and Humanities 2015 Niedersachsenprofessur 2016–2019 2016 Hall of Fame of German Research 2017 Jacob-Henle-Medal 2016 2018 European Inventor Award in Research category for "Improved magnetic resonance imaging (MRI)" especially in Fast low angle shot magnetic resonance imaging (FLASH MRI). 2020 Werner von Siemens Ring Memberships 1995 Fellow of the Society of Magnetic Resonance in Medicine 2005 Akademie der Wissenschaften zu Göttingen 2020 acatech (German Academy for Technical Sciences) References External links Biomedizinische NMR: Detailed information about scientific projects and recent results Max Planck Institute for Multidisciplinary Sciences: Further general information 1951 births Living people 20th-century German physicists 20th-century German biologists German physical chemists 21st-century German physicists