can be due to either familial short stature or constitutional growth delay(CGD). Familial short stature is indicative when one or both parents are of a short stature, and the height and weight percentiles are under the 5 percentile threshold. The child will be concordant with the mean parental height, and the bone age should be normal. Constitutional growth delays are marked by low height and weight percentiles as early as the first 4–6 months following birth. Genetic Syndromes A variety of genetic syndromes can result growth chart patterns with a typical pattern. Genetic diseases such as Turner's syndrome, Prader Willi, and Noonan syndrome can be marked by a less than 5th percentile height and weight since birth., Other genetic disorders such as Marfan's syndrome and Klinefelter's syndrome are typically indicated by a height above the 90th percentile. Endocrine and Metabolic Disorders A decrease of height velocity with retained or increased weight velocity can be indicative of endocrine disorders including hypothyroidism, growth hormone deficiency, and excess of glucocorticoids. Variability in Growth Charts The CDC's growth chart is utilized from a population that consists of a representative population in the USA. Charts based on a specific race or ethnicity are not useful because of the growth chart progression can be attributed to socioeconomic factors. WHO launched a revised growth in 2006 chart using children from Ghana, Oman, Norway, Brazil, India and the USA that substantiated the fact that growth is highly dependent on environmental factors. See also Failure to thrive, a growth disorder Weight and height percentile Endocrine disease Constitutional growth delay Growth hormone deficiency Intrauterine growth restriction Obesity References External links CDC information on growth charts WHO information on growth charts The WHO Child Growth Standards Growth Charts and Breastfeeding Babies Pediatrics