dramatically longer than wild-type flies. In the tiny roundworm Caenorhabditis elegans, loss-of-function mutants of JNK-1 have a decreased life span, while amplified expression of wild-type JNK-1 extends life span by 40%. Worms with overexpressed JNK-1 also have significantly increased resistance to oxidative stress and other stresses. See also References External links Getting a Handle on Cellular JNK (from Beaker Blog) MAP Kinase Resource EC 2.7.11