is an intermediate metabolite of ethanol and is responsible for most symptoms of a hangover; its effect on autonomic β receptors is responsible for the vasomotor symptoms. Treatment involves reassuring the patient that the often frightening symptoms will pass, rehydration (fluid replacement) for fluid loss from vomiting, and monitoring for cardiac arrhythmias. Large and prolonged doses of coprine were found to have gonadotoxic effects on rats and dogs in testing. See also List of Coprinopsis species Notes References Further reading Acetaldehyde dehydrogenase inhibitors Edible fungi Fungi described in 1786 Fungi of Europe Fungi of North America atramentaria Taxa named by Jean Baptiste François Pierre Bulliard