This list contains a list of EC numbers for the fourth group, EC 4, lyases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. All official information is tabulated at the website of the committee. The database is developed and maintained by Andrew McDonald. EC 4.1: Carbon-Carbon Lyases EC 4.1.1: Carboxy-lyases : pyruvate decarboxylase : oxalate decarboxylase EC 4.1.1.3: Now recognized to be two enzymes [oxaloacetate decarboxylase (Na+ extruding)] and (oxaloacetate decarboxylase). : acetoacetate decarboxylase : acetolactate decarboxylase : cis-aconitate decarboxylase : benzoylformate decarboxylase : oxalyl-CoA decarboxylase : malonyl-CoA decarboxylase EC 4.1.1.10: Now included with , aspartate 4-decarboxylase : aspartate 1-decarboxylase : aspartate 4-decarboxylase EC 4.1.1.13: deleted : valine decarboxylase : glutamate decarboxylase : hydroxyglutamate decarboxylase : ornithine decarboxylase : lysine decarboxylase : arginine decarboxylase : diaminopimelate decarboxylase : phosphoribosylaminoimidazole carboxylase : histidine decarboxylase : orotidine-5′-phosphate decarboxylase : aminobenzoate decarboxylase : tyrosine decarboxylase EC 4.1.1.26: Now included with aromatic-L-amino-acid decarboxylase EC 4.1.1.27: Now included with aromatic-L-amino-acid decarboxylase : aromatic-L-amino-acid decarboxylase : sulfoalanine decarboxylase : pantothenoylcysteine decarboxylase : phosphoenolpyruvate carboxylase : phosphoenolpyruvate carboxykinase (GTP) : diphosphomevalonate decarboxylase : dehydro-L-gulonate decarboxylase : UDP-glucuronate decarboxylase : phosphopantothenoylcysteine decarboxylase : uroporphyrinogen decarboxylase : phosphoenolpyruvate carboxykinase (diphosphate) : ribulose-bisphosphate carboxylase : hydroxypyruvate decarboxylase EC 4.1.1.41: Now , (S)-methylmalonyl-CoA decarboxylase : carnitine decarboxylase : phenylpyruvate decarboxylase : 4-carboxymuconolactone decarboxylase : aminocarboxymuconate-semialdehyde decarboxylase : o-pyrocatechuate decarboxylase : tartronate-semialdehyde synthase : indole-3-glycerol-phosphate synthase : phosphoenolpyruvate carboxykinase (ATP) : adenosylmethionine decarboxylase : 3-hydroxy-2-methylpyridine-4,5-dicarboxylate 4-decarboxylase : 6-methylsalicylate decarboxylase : phenylalanine decarboxylase : dihydroxyfumarate decarboxylase : 4,5-dihydroxyphthalate decarboxylase : 3-oxolaurate decarboxylase : methionine decarboxylase : orsellinate decarboxylase : gallate decarboxylase : stipitatonate decarboxylase : 4-hydroxybenzoate decarboxylase : gentisate decarboxylase : protocatechuate decarboxylase : 2,2-dialkylglycine decarboxylase (pyruvate) : phosphatidylserine decarboxylase : uracil-5-carboxylate decarboxylase : UDP-galacturonate decarboxylase : 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase : 3,4-dihydroxyphthalate decarboxylase EC 4.1.1.70: Now , glutaconyl-CoA decarboxylase : 2-oxoglutarate decarboxylase : branched-chain-2-oxoacid decarboxylase : tartrate decarboxylase : indolepyruvate decarboxylase : 5-guanidino-2-oxopentanoate decarboxylase : arylmalonate decarboxylase : 4-oxalocrotonate decarboxylase : acetylenedicarboxylate decarboxylase : sulfopyruvate decarboxylase : 4-hydroxyphenylpyruvate decarboxylase : threonine-phosphate decarboxylase : phosphonopyruvate decarboxylase : 4-hydroxyphenylacetate decarboxylase : D-dopachrome decarboxylase : 3-dehydro-L-gulonate-6-phosphate decarboxylase : diaminobutyrate decarboxylase : malonyl-S-ACP decarboxylase : biotin-independent malonate decarboxylase EC 4.1.1.89: Now , biotin-dependent malonate decarboxylase : peptidyl-glutamate 4-carboxylase : salicylate decarboxylase : indole-3-carboxylate decarboxylase : pyrrole-2-carboxylate decarboxylase : ethylmalonyl-CoA decarboxylase : L-glutamyl-[BtrI acyl-carrier protein] decarboxylase : carboxynorspermidine decarboxylase : 2-oxo-4-hydroxy-4-carboxy-5-ureidoimidazoline decarboxylase * : 4-hydroxy-3-polyprenylbenzoate decarboxylase * :