This list contains a list of EC numbers for the sixth group, EC 6, ligases, placed in numerical order as determined by the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology. All official information is tabulated at the website of the committee. The database is developed and maintained by Andrew McDonald. EC 6.1: Forming Carbon-Oxygen Bonds EC 6.1.1: Ligases Forming Aminoacyl-tRNA and Related Compounds (Aminoacyl tRNA synthetase) : tyrosine—tRNA ligase : tryptophan—tRNA ligase : threonine—tRNA ligase : leucine—tRNA ligase : isoleucine—tRNA ligase : lysine—tRNA ligase : alanine—tRNA ligase : Deleted : valine—tRNA ligase : methionine—tRNA ligase : serine—tRNA ligase : aspartate—tRNA ligase : D-alanine—poly(phosphoribitol) ligase : glycine—tRNA ligase : proline—tRNA ligase : cysteine—tRNA ligase : glutamate—tRNA ligase : glutamine—tRNA ligase : arginine—tRNA ligase : phenylalanine—tRNA ligase : histidine—tRNA ligase : asparagine—tRNA ligase : aspartate—tRNAAsn ligase : glutamate—tRNAGln ligase EC 6.1.1.25: The tRNAPyl is now known only to be charged with pyrrolysine (cf. ) : pyrrolysine—tRNAPyl ligase : O-phospho-L-serine—tRNA ligase EC 6.1.1.28: proline/cysteine—tRNA ligase. Later published work having demonstrated that this was not a genuine enzyme, EC 6.1.1.28 was withdrawn at the public-review stage before being made official EC 6.1.2: Acid—alcohol ligases (ester synthases) : D-alanine—(R)-lactate ligase : nebramycin 5′ synthase * * No Wikipedia article EC 6.1.3: Cyclo-ligases : olefin β-lactone synthetase * * No Wikipedia article EC 6.2: Forming Carbon-Sulfur Bonds EC 6.2.1: Acid-Thiol Ligases : acetate—CoA ligase : medium-chain acyl-CoA ligase : long-chain-fatty-acid—CoA ligase : succinate—CoA ligase (GDP-forming) : succinate—CoA ligase (ADP-forming) : glutarate—CoA ligase : cholate—CoA ligase : oxalate—CoA ligase : malate—CoA ligase : carboxylic acid—CoA ligase (GDP-forming) : biotin—CoA ligase : 4-coumarate—CoA ligase : acetate—CoA ligase (ADP-forming) : 6-carboxyhexanoate—CoA ligase : arachidonate—CoA ligase : acetoacetate—CoA ligase : propionate—CoA ligase : citrate—CoA ligase : long-chain-fatty-acid—protein ligase : long-chain-fatty-acid—[acyl-carrier-protein] ligase EC 6.2.1.21: Activity covered by , phenylacetate—CoA ligase : [citrate (pro-3S)-lyase] ligase : dicarboxylate—CoA ligase : phytanate—CoA ligase : benzoate—CoA ligase : o-succinylbenzoate—CoA ligase : 4-hydroxybenzoate—CoA ligase : 3α,7α-dihydroxy-5β-cholestanate—CoA ligase EC 6.2.1.29: Deleted, identical to , cholate—CoA ligase : phenylacetate—CoA ligase : 2-furoate—CoA ligase : anthranilate—CoA ligase : 4-chlorobenzoate—CoA ligase : trans-feruloyl-CoA synthase : acetate—[acyl-carrier protein] ligase : 3-hydroxypropionyl-CoA synthase : 3-hydroxybenzoate—CoA ligase : (2,2,3-trimethyl-5-oxocyclopent-3-enyl)acetyl-CoA synthase : [butirosin acyl-carrier protein]—L-glutamate ligase : 4-hydroxybutyrate—CoA ligase (AMP-forming) * : 3-[(3aS,4S,7aS)-7a-methyl-1,5-dioxo-octahydro-1H-inden-4-yl]propanoate—CoA ligase * : 3-oxocholest-4-en-26-oate—CoA ligase * : 2-hydroxy-7-methoxy-5-methyl-1-naphthoate—CoA ligase * : 3-(methylthio)propionyl—CoA ligase * : E1 ubiquitin-activating enzyme * : L-allo-isoleucine—holo-[CmaA peptidyl-carrier protein] ligase * : medium-chain-fatty-acid—[acyl-carrier-protein]