the MPAA for "crude language" and "bodily humor" in 2000. However, Warner Bros. edited the film to make it family-friendly; and in 2001 when it was released, the film was re-rated PG on appeal for "bodily humor". Release Marketing The first trailer for Osmosis Jones was released in front of Pokémon 3: The Movie on April 6, 2001, and contains a classical masterpiece from Stanley Kubrick's film 2001: A Space Odyssey. Home media Osmosis Jones was released on VHS and DVD on November 13, 2001. Reception Box office Osmosis Jones had its world premiere screening on August 7, 2001, at the Grauman's Egyptian Theatre before being widely released on August 10, 2001, in 2,305 theaters worldwide. Upon its original release, the film was a financial stump and was the penultimate project produced by Warner Bros. Feature Animation (preceded by The Iron Giant and followed by Looney Tunes: Back in Action, which both also failed at the box office upon their original releases). The film opened at #7 in its first opening weekend at the U.S. box office, accumulating $5,271,248 on its opening week. The film soon grossed $13,596,911. The film was a box office bomb, unable to recover its $70 million production budget. Critical response On Rotten Tomatoes, Osmosis Jones has an approval rating of 56% based on 111 reviews, with an average rating of 5.5/10. The site's critical consensus reads, "The animated portion of Osmosis is zippy and fun, but the live-action portion is lethargic." On Metacritic, the film has a weighted average score of 57 out of 100, based on 28 critics, indicating "mixed or average reviews". Audiences polled by CinemaScore gave the film an average grade of "B−" on an A+ to F scale. The animated parts of Osmosis Jones were praised for their plot and fast pace, in contrast with the criticized live action segments. Robert Koehler of Variety praised the film for its animated and live-action segments intervening, claiming it to be "the most extensive interplay of live-action and animation since Who Framed Roger Rabbit". The New York Times wrote "the film, with its effluvia-festival brand of humor, is often fun, and the rounded, blobby rendering of the characters is likable. But the picture tries too hard to be offensive to all ages. I suspect that even the littlest viewers will be too old for that spit." Roger Ebert gave the film 3 out of