The route continues east through Owego, following Front Street for five blocks before veering southeast onto Fifth Avenue at a junction with John Street. Paralleling the Norfolk Southern tracks once again, NY 17C proceeds southeast alongside a stretch of houses near the Susquehanna River, crossing into the town of Owego. The route soon becomes commercial alongside the river, entering a large trumpet interchange which connects to NY 434 and NY 17 across the Susquehanna. After the interchange, NY 17C crosses over the tracks, bending southeast through Owego, becoming a two-lane residential street. Running alongside the tracks and the Susquehanna again, the route makes another stretch to the northeast, bending southeast through Owego. Soon making a large bend to the south, NY 17C becomes residential, entering the hamlet of Campville. NY 17C through Campville remains residential, serving several homes on both sides of the road. Just after leaving the hamlet of Campville, NY 17C intersects with the northern terminus of NY 962J, a reference route erroneously signed as a touring route. NY 17C continues eastward through the town of Owego, running on an embankment high over the Norfolk Southern tracks, remaining a two-lane residential road as it bends northeast. Running northeast, the route crosses several residential neighborhoods of Owego before crossing the county line into Broome County. Broome County Crossing into Broome County, NY 17C abruptly climbs up the side of Bornt Hill and parallels the tracks and river into the town of Union, entering the urban core of the Binghamton metropolitan area. The route, still bearing the name of Campville Road, runs over the hill to the north and west of Tri-Cities Airport and the Triple Cities to the east become visible for the first time. After passing Glendale Technology Park, a former IBM complex, NY 17C crosses over to the south side of the railroad and passes the En-Joie Golf Course, one of the many remnants of the area's prosperity under Endicott-Johnson. As it takes on the name West Main Street and crosses South Grippen Avenue, NY 17C becomes a residential street, passing numerous single-family homes for a short distance as it crosses the border into Endicott. The route becomes a commercial village street before intersecting with NY 26, Nanticoke Avenue, at the center of downtown Union. Now concurrent, NY 17C and NY 26 pick up an additional lane on each side as they proceed east as East Main