Margaret "Maggie" Scully was portrayed by actor Sheila Larken. Margaret, or "Maggie" as she was called by her husband, Bill Scully, is the mother of Dana Scully and her three siblings: William "Bill" Scully, Jr., Melissa Scully and Charles Scully. Margaret was widowed early in the series, since her husband died of a massive heart attack. She may have a bit of psychic intuition – when Dana is kidnapped, Margaret confessed to Mulder that she had had a premonition about Dana, but was afraid to tell her skeptical daughter. In 2016, Margaret suffered a heart attack and went into a coma. Dana revealed that Margaret's advance healthcare directive allowed life support to be applied, however she was unaware that Margaret had revoked it and replaced it with a DNR a year earlier. After hearing Charles Scully's voice on the phone, Margaret briefly awoke from her coma before passing away, with Mulder and Dana by her side. Her last words to Mulder were "My son is named William, too". Melissa Scully Melissa "Missy" Scully was portrayed by Melinda McGraw as an adult and Rebecca Codling and Lauren Diewold during childhood flashbacks. Melissa was the sister of Dana, Bill and Charles, and the daughter of William and Margaret. Melissa believed in new age mysticism, whereas Dana was a firm believer in hard science. Melissa came to see Dana when she had returned to the hospital after her abduction and claimed she could feel Dana's spirit was still inside her body. After Scully discovered the implant placed in her neck, Melissa suggested her to undertake regression therapy in an attempt to uncover the truth about her abduction. Melissa was shot in the head by mistake by Luis Cardinal and Alex Krycek, who were trying to kill her sister Dana, as she entered Scully's apartment ("The Blessing Way"). As Melissa lay dying in hospital, Dana asked for Albert Hosteen to go and pray for her ailing sister, as he had done for Fox Mulder shortly before. However, Hosteen was not confident of the outcome and Melissa soon died. Dana eventually detained and arrested Cardinal during his assassination attempt on Walter Skinner while Skinner was being transported in an ambulance. Upon being questioned by Dana, Cardinal denied involvement in Melissa's death, implicating Krycek as her killer. However, Cardinal was in fact the trigger man. Cardinal later died in his cell, his death made to look