Spain scarcely budged between the years 1596 and 1696. The disease is generally believed to have been bubonic plague, an infection by the bacterium Yersinia pestis, transmitted via a rat vector. Other symptom patterns of the bubonic plague, such as septicemic plague and pneumonic plague, were also present. See also Second plague pandemic Great Plague of London Great Plague of Vienna Bubonic Plague Black Death in Spain References External links Second plague pandemic History of Seville Health disasters in Spain 17th-century epidemics 1649 disasters 1640s in Spain