during her next tournament, however, in Key Biscayne, defeating Jelena Janković in the third round in three sets – which was the first top 10 victory of her career. She lost in the round of 16 to Anna Chakvetadze. Reaching the fourth round of Key Biscayne has thus far been the best showing of Santangelo's in a high-tier event. During the clay court season, Santangelo defeated Nadia Petrova in the second round of Warsaw, for her second career top-10 victory, reaching her third quarterfinal of the year. She lost to eventual champion Henin. At the French Open, in singles, Santangelo reached the third round, losing to eventual champion Henin. For doubles, however, partnering Alicia Molik, she won the championship, winning her first Grand Slam title. The victory was her fourth title in doubles for the year, with four different partners at each championship. In 2007 Wimbledon Championships, Santangelo was defeated in round three by the defending champion and fourth-seeded, Amélie Mauresmo, in 57 minutes. Santangelo took part in the 2007 Fed Cup final, where she was defeated by Svetlana Kuznetsova in the second rubber and by Elena Vesnina in the fourth rubber; Italy unsuccessfully defended its title and Russia won the trophy with a 4–0 score. Santangelo had to miss the warm-ups for the Australian Open and the Australian Open itself in 2008 because of a troublesome left foot injury. She also had to miss the Paris Indoors event and the Bangalore Open event, where she has previously won a WTA title and been a runner-up. Santangelo returned from eight-month left foot injury lay-off in May; she reached the second round twice (including the 2008 Wimbledon Championships) and she won two ITF tournaments, Biella and Ortisei. At the Beijing Olympics, she was defeated by Dinara Safina in the first round. In 2009, once again plagued by her foot injury, Santangelo won three doubles tournaments, all of them partnering Nathalie Dechy: ASB Classic, where they defeated Nuria Llagostera Vives and Arantxa Parra Santonja, the Monterrey Open with a two-sets win over Iveta Benešová and Barbora Záhlavová-Strýcová and, finally, Strasbourg, defeating Claire Feuerstein and Stéphanie Foretz with a 6–0, 6–1 score. On 6 September, partnering Laura Olivieri, she won the 2009 European Beach Tennis Championships with a straight-sets win over the defending champions, Simona Briganti and Rossella Stefanelli. In May 2010, Santangelo announced her decision to compete in doubles events only, citing