Toothlessness, or edentulism, is the condition of having no teeth. In organisms that naturally have teeth, it is the result of tooth loss. Organisms that never possessed teeth can also be described as edentulous. Examples are the members of the former zoological classification order of Edentata, which included anteaters and sloths, as they possess no anterior teeth and no or poorly developed posterior teeth. In naturally dentate species, edentulism is more than just the simple presence or absence of teeth. It is biochemically complex because the teeth, jaws, and oral mucosa are dynamic (changing over time). Processes such as bone remodeling (loss and gain of bone tissue) in the jaws and inflammation of soft tissue in response to the oral microbiota are clinically important for edentulous people. For example, bone resorption in the jaw is frequently how the teeth were able to detach in the first place; the jaw in an edentulous area undergoes further resorption even after the teeth are gone; and insertion of dental implants can elicit new bone formation, leading to osseointegration. Meanwhile, bacteria and yeasts of the oral cavity and the immune system of their host create an immensely complicated and constantly changing interplay that presents clinically as gingivitis, caries, stomatitis, and other periodontal pathology. Signs and symptoms For people, the relevance and functionality of teeth can be easily taken for granted, but a closer examination of their considerable significance will demonstrate how they are actually very important. Among other things, teeth serve to: support the lips and cheeks, providing for a fuller, more aesthetically pleasing appearance maintain an individual's vertical dimension of occlusion along with the tongue and lips, allow for the proper pronunciation of various sounds preserve and maintain the height of the alveolar ridge cut, grind, and otherwise chew food Tooth loss also has a psychological impact: it has been shown to generally lower a patient's quality of life, with this compromised oral function leading to decreased self-esteem and a decline is psychological well-being. Patients may be embarrassed to smile, eat and talk. Facial support and aesthetics When an individual's mouth is at rest, the teeth in the opposing jaws are nearly touching; there is what is referred to as a "freeway space" of roughly 2–3 mm. However, this distance is partially maintained as a result of the teeth limiting any further closure past the point of maximum intercuspidation. When there are no