pre-dated the establishment of the Portuguese nation, a point that shaped relations between the two. Under Afonso Henriques (r. 1139–1185), the first king of Portugal and the founder of the Portuguese Kingdom, church and state were unified into a lasting and mutually beneficial partnership. To secure papal recognition of his country, Afonso declared Portugal a vassal state of the Pope, and was as such recognized in 1179 through the papal bull Manifestis Probatum. The King found the Church to be a useful ally as he drove the Moors towards the South. For its support of his policies, Afonso richly rewarded the Church by granting it vast lands and privileges in the conquered territories. The Church became the country's largest landowner, and its power came to be equal to that of the nobility, the military orders, and even, for a time, the Crown. But Afonso also asserted his supremacy over the Church, a supremacy that — with various ups and downs — was maintained. Although relations between the Portuguese State and the Catholic Church were generally amiable and stable, their relative power fluctuated. In the 13th and 14th centuries, the Church enjoyed both riches and power stemming from its role in the reconquest and its close identification with early Portuguese nationalism. For a time, the Church's position vis-à-vis the State diminished until the growth of the Portuguese Overseas Empire made its missionaries important agents of colonization (see, for example, Kingdom of Kongo). Until the 15th century, some Jews occupied prominent places in Portuguese political and economical life. For example, Isaac Abrabanel was the treasurer of King Afonso V of Portugal. Many also had an active role in the Portuguese culture, and they kept their reputation of diplomats and merchants. By this time, Lisbon and Évora were home to important Jewish communities. In 1497, reflecting events that had occurred five years earlier in Spain, Portugal expelled the Jews and the few remaining Moors — or forced them to convert. In 1536, the Pope gave King João III (r. 1521–1557) permission to establish the Portuguese Inquisition to enforce the purity of the faith. Earlier, the country had been rather tolerant, but now orthodoxy and intolerance reigned. The Jesuit Order was placed in charge of all education. In the 18th century, anti-Church sentiment became strong. The Marquês de Pombal (r. 1750–1777) expelled the Jesuits in 1759, broke relations with the Holy See in Rome,