reputed to have replied "that the matter was easily accounted for: For that his discourse was his own, his actions were the ministry's". Great Plague and Great Fire In 1665, the Great Plague of London began, peaking in September with up to 7,000 deaths per week. Charles, his family, and the court fled London in July to Salisbury; Parliament met in Oxford. Plague cases ebbed over the winter, and Charles returned to London in February 1666. After a long spell of hot and dry weather through mid-1666, the Great Fire of London started on 2 September 1666 in Pudding Lane. Fanned by strong winds and fed by wood and fuel stockpiled for winter, the fire destroyed about 13,200 houses and 87 churches, including St Paul's Cathedral. Charles and his brother James joined and directed the firefighting effort. The public blamed Catholic conspirators for the fire. Foreign policy and marriage Since 1640, Portugal had been fighting a war against Spain to restore its independence after a dynastic union of sixty years between the crowns of Spain and Portugal. Portugal had been helped by France, but in the Treaty of the Pyrenees in 1659 Portugal was abandoned by its French ally. Negotiations with Portugal for Charles's marriage to Catherine of Braganza began during his father's reign and upon the restoration, Queen Luísa of Portugal, acting as regent, reopened negotiations with England that resulted in an alliance. On 23 June 1661, a marriage treaty was signed; England acquired Catherine's dowry of Tangier (in North Africa) and the Seven Islands of Bombay (the latter having a major influence on the development of the British Empire in India), together with trading privileges in Brazil and the East Indies, religious and commercial freedom in Portugal and two million Portuguese crowns (about £300,000); while Portugal obtained military and naval support against Spain and liberty of worship for Catherine. Catherine journeyed from Portugal to Portsmouth on 13–14 May 1662, but was not visited by Charles there until 20 May. The next day the couple were married at Portsmouth in two ceremonies—a Catholic one conducted in secret, followed by a public Anglican service. The same year, in an unpopular move, Charles sold Dunkirk to his first cousin King Louis XIV of France for about £375,000. The channel port, although a valuable strategic outpost, was a drain on Charles's limited finances, as it cost the Treasury £321,000 per year. Before