Dr. No is the sixth novel by the English author Ian Fleming to feature his British Secret Service agent James Bond. Fleming wrote the novel in early 1957 at his Goldeneye estate in Jamaica. It was first published in the United Kingdom by Jonathan Cape on 31 March 1958. The novel centres on Bond's investigation into the disappearance in Jamaica of two fellow MI6 operatives. He establishes that they had been investigating Doctor No, a Chinese operator of a guano mine on the fictional Caribbean island of Crab Key. Bond travels to the island and meets Honeychile Rider and later Doctor No. The novel began as a 1956 screenplay for the producer Henry Morgenthau III for a proposed television show entitled Commander Jamaica. When those plans foundered, Fleming adapted the ideas as the basis for a novel, provisionally titled The Wound Man. The book's eponymous villain was influenced by Sax Rohmer's Fu Manchu stories. Dr. No was the first of Fleming's novels to face widespread negative criticism in Britain; Paul Johnson of the New Statesman dismissed the book as one of "Sex, Snobbery and Sadism". When released on the American market it was received more favourably. Dr. No was serialised in the Daily Express, first in an abridged story form and later as a comic strip. The story was adapted in 1962 as the first film in the Bond series, with Sean Connery in the lead role; in 2008 BBC Radio 4 broadcast a version with Toby Stephens as Bond. Plot After recovering from serious poisoning inflicted by the SMERSH agent Rosa Klebb (in From Russia, with Love) the MI6 agent James Bond is sent by his superior, M, on an undemanding mission to the British colony of Jamaica. He is instructed to investigate the disappearance of Commander John Strangways, the head of MI6's Station J in Kingston, and his secretary. Bond is briefed that Strangways had been investigating the activities of Doctor Julius No, a reclusive Chinese-German who lives on the fictional island of Crab Key and runs a guano mine. The island has a colony of roseate spoonbills at one end while local rumour is that a vicious dragon also lives there. The spoonbills are protected by the American National Audubon Society, two of whose representatives died when their plane crashed on No's airstrip. On his arrival in Jamaica, Bond soon realises that he is being watched. His