Dr. Mario is a 1990 puzzle video game developed and published by Nintendo for the Nintendo Entertainment System, Famicom, and Game Boy. It was produced by Gunpei Yokoi and designed by Takahiro Harada. The soundtrack was composed by Hirokazu Tanaka. It is a falling block puzzle game, where the player's objective is to destroy the viruses populating the on-screen playing field by using colored vitamin capsules that are automatically tossed into the field by Dr. Mario. The player manipulates the falling capsules, to align the same colors, which destroys viruses. The player progresses through the game by eliminating all the viruses on the screen in each level. Dr. Mario was a commercial success, with more than copies sold worldwide across all platforms. It received generally positive reviews, appearing on several lists of "Best Nintendo Games of All Time". It has been ported, remade, or had a sequel on every Nintendo home console since the NES, and on most portable consoles, including a re-release in 2004 on the Game Boy Advance in the Classic NES Series. It was modified into minigames in WarioWare, Inc.: Mega Microgames!, Brain Age 2: More Training in Minutes a Day!, and Brain Age: Concentration Training. Dr. Luigi is a spin-off for Wii U, released in 2013 as part of the Year of Luigi celebration. Gameplay Dr. Mario is a falling block tile-matching video game. Mario assumes the role of a doctor, tossing two-colored medical capsules into a medicine bottle representing the playing field. This area is populated by viruses of three colors — red, yellow, and blue — which stay in their starting positions until removed. In a style similar to Tetris, the player manipulates each capsule as it vertically falls, able to move it left or right and rotate it 90 degrees clockwise or counter-clockwise. When matching colors of capsule halves and viruses touch sequentially 4-in-a-row, they disappear. Any remaining half or whole capsules which are not supported will fall to the bottom of the playing field or until hitting another supported object, and any new 4-in-a-row alignments also disappear. The main objective is to eliminate all viruses from the playing field, finishing each level. A game over occurs if capsules fill the playing field in a way that obstructs the bottle's narrow neck. After each 5th level is completed on Medium or High difficulty, up to level 20, a cutscene shows the virus trio