used in military applications (dual-use research), so biosecurity protocols are used to prevent dangerous biological materials from falling into the hands of malevolent parties. Laboratory program Components of a laboratory biosecurity program include: Physical security Personnel security Material control and accountability Transport security Information security Program management Biological Security Animals and plants Threats to animals and plants, in particular food crops, which may in turn threaten human health, are typically overseen by a government department of agriculture. Animal biosecurity encompasses different means of prevention and containment of disease agents in a specific area. A critical element in animal biosecurity is biocontainment – the control of disease agents already present in a particular area and work to prevent transmission. Animal biosecurity may protect organisms from infectious agents or noninfectious agents such as toxins or pollutants, and can be executed in areas as large as a nation or as small as a local farm. Animal biosecurity takes into account the epidemiological triad for disease occurrence: the individual host, the disease, and the environment in contributing to disease susceptibility. It aims to improve nonspecific immunity of the host to resist the introduction of an agent, or limit the risk that an agent will be sustained in an environment at adequate levels. Biocontainment works to improve specific immunity towards already present pathogens. The aquaculture industry is also vulnerable to pathogenic organisms, including fungal, bacterial, or viral infections which can affect fish at different stages of their life cycle. Human health Direct threats to human health may come in the form of epidemics or pandemics, such as the 1918 Spanish flu pandemic and other influenza epidemics, MERS, SARS, or the COVID-19 pandemic, or they may be deliberate attacks (bioterrorism). The country/federal and/or state health departments are usually responsible for managing the control of outbreaks and transmission and the supply of information to the public. Medical countermeasures Medical countermeasures (MCMs) are products such as biologics and pharmaceutical drugs that can protect from or treat the effects of a chemical, biological, radiological, or nuclear (CBRN) attack or in the case of public health emergencies. MCMs can also be used for prevention and diagnosis of symptoms associated with CBRN attacks or threats. In the US, the Food and Drug Administration (FDA) runs a program called the "FDA Medical Countermeasures Initiative" (MCMi), with programs funded by the federal government. It helps support "partner" agencies and organisations prepare for public