have examined biomarkers that result from the oxidation of 7DHC, such as DHCEO. It is likely that as animal models are improved, they will lead to many more discoveries in SLOS research. Eponym It is named after David Weyhe Smith (1926–1981), an American pediatrician; Luc Lemli (1935–), a Belgian physician; and John Marius Opitz (1935–), a German-American physician. These are the researchers who first described the symptoms of SLOS. References External links GeneReview/UW/NIH on Smith–Lemli–Opitz syndrome Autosomal recessive disorders Cholesterol and steroid metabolism disorders Genodermatoses Rare diseases Syndromes affecting head size Syndromes affecting the nervous system Syndromes with short stature