HPM may refer to: Harbarian process modeling Hargeisa Provincial Museum, in Hargeisa, Somalia Haystack Prayer Meeting, held in Williamstown, Massachusetts, in 1806 High-power microwave, directed-energy weapon using electromagnetic radiation high performance mobile, a semiconductor production type parametric variant of TSMC Hospice and Palliative Medicine, a medical specialty that focuses on symptom management, relief of suffering and end-of-life care Human performance modeling Human Potential Movement, self-improvement movement of the 1960s Hydrogen-moderated self-regulating nuclear power module, a type of nuclear power generator A high proper motion star High performance material, type of special technical plastic High Performance Process Manager - type of Honeywell-produced device widely used in industry to control chemical and refining processes Honda Prospect Motor, an automobile manufacturing company