an upset win over the No. 6 Florida Gators in Gainesville and a shootout win over Ole Miss in the season finale. In March 2021, a woman testifying in front of Louisiana state legislators claimed that she had reported an instance of sexual harassment by LSU running back Derrius Guice to Orgeron, but that the coach had taken no action against him, and in fact called the woman and asked her to forgive Guice. In June 2021, Orgeron was added as a defendant to a Title IX lawsuit against LSU, which alleges that the coach was told Guice had raped a student and did not report the allegation. Despite high expectations and a favorable schedule, LSU stumbled to a 3–3 start in 2021, losing several games in which they were favored. Following the tumultuous start, Orgeron’s Tigers were able to upend the No. 20-ranked Florida Gators in a thrilling rivalry game matchup. Despite the victory, LSU administrators announced the following day, on October 17, 2021, that they had reached a mutual agreement for Orgeron to leave the program at the end of the 2021 season. Orgeron's last game was a last-second victory against Texas A&M at home, which allowed the Tigers to finish the season at 6–6 and become bowl eligible. Despite this, Orgeron announced shortly after the game that he would not coach in the bowl game, and that offensive line coach Brad Davis would be appointed interim coach. In media Orgeron appears as himself in the 2009 film The Blind Side recruiting Michael Oher. In 2005, Orgeron had won an intense recruiting battle for Oher. Director John Lee Hancock contacted Orgeron about playing himself, despite having been fired by Ole Miss prior to the filming of the movie. Orgeron agreed and impressed the filmmaker with his enthusiasm. In 2006, Bruce Feldman, then a senior writer at ESPN The Magazine, was allowed in-depth access to the Ole Miss program for a book about the recruiting process at a big-time college football program. The result was 2007's Meat Market: Inside the Smash-Mouth World of College Football Recruiting, a book filled with anecdotes about Orgeron, which The New York Times described as "one of the most insightful books ever written about college football." Orgeron was portrayed by Emmett Skilton in the TV series Young Rock, which is about actor and former wrestler Dwayne "The Rock" Johnson. Orgeron was Johnson's defensive line