lactate (Lac-Hydrin) are used to facilitate the release of retained corneocytes. oral isotretinoin acitretin The topical receptor-selective retinoid tazarotene Research is ongoing with regard to the use of gene therapy to treat XLI. Timber Pharmaceuticals is planning on conducting a phase 3 trial of its investigational topical isotretinoin product in the second quarter of 2022 for the treatment of congential ichthyosis. History In the 1960s, recessive x-linked ichthyosis was distinguished clinically from other ichthyoses. See also Ichthyosis Carvajal syndrome References External links Genodermatoses Cholesterol and steroid metabolism disorders Rare diseases