tribes, especially the Yamasee for most of his military force. On news of the outbreak of Queen Anne's War in 1702, he led 500 colonists, 300 native allies, and 14 small ships on an invasion of Spanish Florida along the coast, destroying the remaining Spanish missionary Indians of Guale and Mocama, and devastating the lands around St. Augustine. While the town of St. Augustine was razed, its central fortress, Castillo de San Marcos, where the Spanish and numerous allied Indians had taken refuge, resisted Moore's siege. The 1702 campaign was viewed as a disaster due to the failure to take the fortress and the expenses incurred, and Moore resigned his post. In 1704, Moore led an expedition of 50 colonists and 1,000 Muscogee, Yamasee, and other allied Indians, into western Florida, leading to the Apalachee massacre. The Apalachee were the last powerful Spanish-allied Indian nation in the region. Their defeat in 1704 resulted in many Apalachee being enslaved and taken from Charleston to the West Indies. Other Apalachee were relocated (some voluntarily, others not) to the Savannah River to live in semi-serfdom. Another result of the defeat of the Apalachee was the collapse of the final defence of the Indians of Florida. In the following years, Carolinian and Indian slave raiders virtually wiped out the Indian population of Florida all the way to the Florida Keys. Moore's defeat of the Apalachee in Spanish Florida was hailed as a major victory for Carolina, which had been fighting with the Spanish for control of the region for decades. It also served to strengthen ties between various southeastern Indians and Carolina. The Creek people and the Cherokees became much more closely allied with Carolina. With these two Indian nations as strong allies, the English rose to a position of dominance over the French and Spanish in the American southeast. Moore died in 1706 of a tropical disease, possibly yellow fever. He was significantly in debt. His son by the same name was elected to the same office in 1719 following the overthrow of the proprietary governor. Personal life Moore married Margaret Berringer, daughter of Lady Margaret Yeamans (by a previous marriage). Their daughter, Mary Moore, married Job Howe, another of the "Goose Creek Men". Altogether James and Margaret had ten children, many of whom moved to the Lower Cape Fear region, where they and their descendants became known as "The Family", the most