extraordinary definition by a pope or ecumenical council (extraordinary universal Magisterium), or those teachings infallibly taught to be revealed by the ordinary universal Magisterium. As in the case of the Immaculate Conception or the Assumption, these doctrines were held by the church prior to the date of official definition, but open for discussion. From the date of definition, they must be accepted by all members of the Catholic Church as contained specifically in the Deposit of Faith and owed supernatural faith in itself (de fide credenda). There are four Marian dogmas specifically defined by the Magisterium among a large number of other dogmas and doctrines about the Virgin Mary – for example, the Annunciation of Mary is dogma because it is in the scriptures, but it has not been formally defined by the Magisterium. These four Marian dogmas include: Mother of God Mary's motherhood of God (Deipara in Latin) is a dogma of the Catholic Church. The term "Mother of God" appears within the oldest known prayer to Mary, the Sub tuum praesidium, which dates to around 250 AD: "Under thy protection we seek refuge, Holy Mother of God". This was the first specifically Marian doctrine to be formally defined by the church, formally affirmed at the Third Ecumenical Council held at Ephesus in 431. This refuted the objection raised by Patriarch Nestorius of Constantinople. Scriptural basis for the dogma is found in John 1:14 which states "And the Word became flesh, and dwelt among us" and in Galatians 4:4 which states "God sent forth his Son, born of a woman, born under the law". Luke 1:35 further affirms divine maternity by stating: "The holy Spirit will come upon you. ... Therefore the child to be born will be called holy, the Son of God." The dogmatic constitution Lumen gentium at the Second Vatican Council affirmed Mary as the Mother of God. "The Virgin Mary, who at the message of the angel received the Word of God in her heart and in her body and gave Life to the world, is acknowledged and honored as being truly the Mother of God and Mother of the Redeemer." This dogma is inherently related to the Christological dogma of the hypostatic union which relates the divine and human natures of Jesus Christ. The Catechism of the Catholic Church teaches that "Mary is truly 'Mother of God' since she is the mother of the