cutaneous angiosarcoma Angiosarcoma in the skin (usually the head or neck and specifically the scalp) with no underlying risk factors such as lymphedema or radiation therapy. Lymphedema associated angiosarcoma Also called Stewart-Treves syndrome, it is a lymphangiosarcoma resulting from chronic lymphedema, swelling due to the build up of lymphatic fluid. It typically happens in the breast following a mastectomy that removes the lymph nodes of the breast. However it can happen anywhere. Parenchymal angiosarcoma Angiosarcoma in parenchymal organs such as the liver, breast or heart. These makes up about 40% of angiosarcoma. Primary breast angiosarcoma This refers to angiosarcoma of the breast without underlying causes such as radiation therapy or lymphedema. It is rare and makes up only 0.04% of breast tumors and 8% of breast sarcomas. It is very aggressive, usually presents in younger females and is often noticeable by a palpable mass. Prognosis is poor with a five-year survival between 8 and 50%. Secondary breast angiosarcoma These are angiosarcoma that arise in the breast from underlying causes such as lymphedema or radiation, usually from radiation therapy for breast cancer. The link between radiation therapy and angiosarcoma has been disputed by some who profess the angiosarcoma is caused by concurrent lymphedema. Secondary breast angiosarcoma tends to have a bad prognosis. Radiation-associated angiosarcoma has a five-year survival of 10 to 54%. Distant metastases are present in 27–42% of individuals and is associated with a far worse prognosis. Other prognostic factors include size of tumor, age and how much can be removed by surgery. Primary brain angiosarcoma Primary brain angiosarcoma are angiosarcoma that arise in the brain (i.e. not metastasised from elsewhere). They are exceedingly rare with only a few cases reported. Imaging is non specific and differential diagnosis includes most other brain tumors such as gliomas or cavernomas, requiring biopsy to confirm diagnosis, usually after surgery. Prognosis is generally poor with a median survival rate of eight months. However it varies greatly depending on whether or not the tumor has metastasised, some individuals may be rid of the disease following surgery, chemotherapy and radiation therapy. Primary cardiac angiosarcoma Primary cardiac angiosarcoma is an angiosarcoma that arises in the heart. Despite being very rare they are the most common malignant primary heart tumor with 10–25% of cases being angiosarcomas. Symptoms may include shortness of breath, chest pain (46%), hypotension and syncope. Superior vena cava syndrome is reportedly a complication of cardiac