in A Population History of North America Michael R. Haines and Richard Hall Steckel (Eds.), Cambridge University Press, 2000, . 1490s in the Caribbean 15th-century epidemics 16th-century epidemics 17th-century epidemics 18th-century epidemics African slave trade Age of Discovery Disease transmission Epidemiology European colonization of the Caribbean Health in the Caribbean History of Hispaniola History of indigenous peoples of North America History of indigenous peoples of the Americas History of the Caribbean History of the Colony of Santo Domingo Indigenous health Portuguese colonization of the Americas Spanish colonization of the Americas