match, have sometimes been pointed out by annoyed researchers preoccupied by the idea that because the archetypal form of acronyms originated with one-to-one letter matching, there must be some impropriety in their ever deviating from that form. However, the raison d'être of clinical trial acronyms, as with gene and protein symbols, is simply to have a syntactically usable and easily recalled short name to complement the long name that is often syntactically unusable and not memorized. It is useful for the short name to give a reminder of the long name, which supports the reasonable censure of "cutesy" examples that provide little to no hint of it. But beyond that reasonably close correspondence, the short name's chief utility is in functioning cognitively as a name, rather than being a cryptic and forgettable string, albeit faithful to the matching of letters. However, other reasonable critiques have been (1) that it is irresponsible to mention trial acronyms without explaining them at least once by providing the long names somewhere in the document, and (2) that the proliferation of trial acronyms has resulted in ambiguity, such as 3 different trials all called ASPECT, which is another reason why failing to explain them somewhere in the document is irresponsible in scientific communication. At least one study has evaluated the citation impact and other traits of acronym-named trials compared with others, finding both good aspects (mnemonic help, name recall) and potential flaws (connotatively driven bias). Some acronyms are chosen deliberately to avoid a name considered undesirable: For example, Verliebt in Berlin (ViB), a German telenovela, was first intended to be (All for Love), but was changed to avoid the resultant acronym ANAL. Likewise, the Computer Literacy and Internet Technology qualification is known as CLaIT, rather than CLIT. In Canada, the Canadian Conservative Reform Alliance (Party) was quickly renamed to the "Canadian Reform Conservative Alliance" when its opponents pointed out that its initials spelled CCRAP (pronounced "see crap"). Two Irish Institutes of Technology (Galway and Tralee) chose different acronyms from other institutes when they were upgraded from Regional Technical colleges. Tralee RTC became the Institute of Technology Tralee (ITT), as opposed to Tralee Institute of Technology (TIT). Galway RTC became Galway-Mayo Institute of Technology (GMIT), as opposed to Galway Institute of Technology (GIT). The charity sports organization Team in Training is known as "TNT" and not "TIT". Technological Institute of Textile & Sciences, however, is still