DFE or DfE may refer to: Organizations Department for the Economy, Northern Ireland Department for Education, UK DePatie–Freleng Enterprises, a defunct animation company Science Dilated fundus examination of the eye Distribution of fitness effects Dietary folate equivalent, bioavailability of folate Technology Decision Feedback Equalizer Design-focused evaluation of educational quality Design for the Environment of a product or service DFE Ascender, an ultralight aircraft Other Dragon Fli Empire, a Canadian hip hop group Dunfermline Town railway station, Scotland, National Rail station code