Dopamine is a 2003 romantic comedy-drama film written and directed by Mark Decena. Plot Rand is a computer animator, who has created an artificial intelligence creature designed to interact with children and teach them responsibility. When his prototype is forced into practice at a school, Rand encounters Sarah, a teacher he was inexplicably drawn to, at his favorite bar one fateful evening. Sparks fly between them, but fundamental differences in their approaches to love and relationships slow them down to a halt. Cast John Livingston as Rand Sabrina Lloyd as Sarah Bruno Campos as Winston Rueben Grundy as Johnson Kathleen Antonia as Tammy Nicole Wilder as Machiko William Windom as Rand's father Dennis Yen as Toru Natalie Decena in the womb Reception Critical response On Rotten Tomatoes it has a 52% rating based on 52 reviews. On Metacritic it has a score of 52 out of 100 based on 23 reviews, indicating "mixed or average reviews". Awards Won the Alfred P. Sloan Prize at the 2003 Sundance Film Festival Nomination for Grand Jury Prize at the 2003 Sundance Film Festival. References External links 2003 films 2003 independent films 2003 romantic comedy-drama films American romantic comedy-drama films Alfred P. Sloan Prize winners Films about artificial intelligence Films set in San Francisco Films set in the San Francisco Bay Area Films shot in San Francisco American independent films Sundance Film Festival award winners 2003 comedy films 2003 drama films 2000s English-language films 2000s American films