a side effect of gods' attacks. Other humans become demons and the Earthlings start to win over the gods. However, the gods divide themselves and possess human bodies to fight. In the ensuing war, the demons are defeated because Dante hesitates to kill Eve, a giant made out of human bodies, when he sees Olga is part of her. But Dante's soul is not destroyed and he promises to return to defeat the gods. Twenty thousand years later, in 2010, high school student Ryo Utsugi is having nightmares about a woman, a city being destroyed by flames and a demon trapped in ice, while Medusa is reborn and is trying to communicate with Dante through Satanist rituals. Meanwhile, a religious group called , secretly commanded by Ryo's father, Kosuke, is trying to revive the gods and is hunting demons through a division named . One day, Ryo intervenes in an assault of Guardian Justice; in response its leader, Sosuke Oshiba, who is also Ryo's schoolmate and kendo club's captain, does a demonstration to Ryo of the existence of demons by killing one. Although Ryo feels a pain in his chest when the creature is killed, he joins the group. Medusa infiltrates Ryo's school as a teacher named to make him remember he is Dante. She also helps the Satanists to kidnap Ryo's sister, , whom they want to sacrifice in a Black Mass. When Medusa is captured by God's Soul, Ryo helps her when she convinces him she is the only one who can save Aya and tells him he is Dante's reincarnation. Medusa and Ryo arrive in the Black Mass just as the Guardian Justice attacks the ritual and prevent Aya's sacrifice. Amidst the conflict, the Satanists summon a mindless demon Dante, who cannot distinguish between friends or foes and eventually eats Ryo. Ryo reappears on Demon Lord Dante's forehead and realizes he controls its body. Shocked, Ryo denies being a demon and releases himself from Dante's body, which makes Dante disappear and transform Ryo into a human-like demon. He returns home after being defeated by traitor demon Zenon but when footage of him in Dante's body is shown on television he flees from his home. Five years later, a worldwide war between demons and gods started. Ryo is hidden in a refugee camp as he does not want to get involved, but Zenon attacks him and Dante recovers