poor. This is most commonly seen in Chesapeake Bay Retrievers, St. Bernards, Great Danes, Newfoundlands, Collies, and Labrador Retrievers. Dysautonomia is primarily seen in cats. Symptoms include vomiting, depression, anorexia, weight loss, dilated pupils, third eyelid protrusion, sneezing, slow heart rate, and megaesophagus. The prognosis is poor and supportive treatment is necessary. Recovery in cats may take up to one year. Giant axonal neuropathy is a rare disease in the German Shepherd dog. It usually becomes evident between the ages of 14 and 16 months. Symptoms include rear limb weakness, decreased reflexes, muscle atrophy, megaesophagus, and loss of bark. No treatment is known and it has a poor prognosis. Hyperchylomicronemia or hyperlipoproteinemia is a type of inherited hyperlipidemia in cats. Polyneuropathy is caused by stretching or compression of nerves near bone by xanthomas, which are lipid deposits. It can cause Horner's syndrome, facial nerve paralysis, and femoral nerve, tibial nerve, radial nerve, trigeminal nerve, or recurrent laryngeal nerve paralysis. Hypertrophic neuropathy is also known as canine inherited demyelinative neuropathy (CIDN) and is inherited in the Tibetan Mastiff. Symptoms usually start between the ages of 7 and 10 weeks, and include weakness, decreased reflexes, and loss of bark. Sensory function remains, but a poor gait or an inability to walk may present. With no treatment available, the prognosis is guarded. The trait is inherited as an autosomal recessive. Hypoglycemia-induced polyneuropathy is especially seen in conjunction with insulinoma. Myasthenia gravis Polyradiculoneuritis is inflammation of the nerve roots. The most common type is Coonhound paralysis. This is similar to Guillain–Barré syndrome in humans. Coonhound paralysis seems to be secondary to a raccoon bite, probably due to some factor in the saliva. However, it can also occur without any interaction with a raccoon. It can happen in any breed of dog. When associated with a raccoon bite, the symptoms start 7 to 11 days after the bite, and include rear leg weakness progressing rapidly to paresis, and decreased reflexes. When not associated with a raccoon bite, the same symptoms occur, with the paresis taking about 3–4 days to reach its maximum effect. Severe cases have a loss of bark, trouble breathing, and an inability to lift the head. Typically, the duration of the paralysis is 2 to 3 months, but can last up to 6 months. Treatment is proper nursing care, and the prognosis is good in mild cases. In bad cases, the dog