unique monograph of 1912, Die Migrane, contains a thoroughly structured survey of most earlier authors, precise clinical observations, a critical evaluation of pathophysiology, and uncritical opinions on treatment, including arsenic cures." In his monograph, Flatau presented the full clinical picture of migraine and described the disease as an innate disposition to pathological metabolic processes in the nervous system and described its distinguished characters – ocular, epileptic, mental and facial. The book was based on observations of himself and about 500 cases from his own practice. In the introduction to the monograph, he wrote,"Migraine, as such, is not an independent or autonomous disease; it is just one set of symptoms in the great chain of changed neurometabolism, whose crucial aspect are chemical changes and endocrine glands. Migraine attack is the expression of brain disorders; however, an exact mechanism which may be responsible is currently just a matter of conjecture and supposition. Today [1912] we cannot describe mechanisms that come to play and express them in well defined anatomical and physiological aspects. The forces that govern such mechanisms are also not known to us. We can only guess and make assumptions as to their operation. Nevertheless, great progress characterizing the development of neurology in the second half of the nineteenth century is visible in the field of research into migraine as well. As a result, one can describe some of the ideas on more reliable anatomical and physiological grounds." Psychiatry In addition to neurology, Flatau was a psychiatrist. Irena Solska, famous Polish actress, describes in her memoirs that playing Maria, a mad wife in nondivine comedy of Zygmunt Krasinski around 1920, she visited the psychiatric hospital (ward) of Edward Flatau. Another of his patients was well-known Polish poet Jan Lechoń. In the story of Isaac Bashevis Singer, "The Power of Darkness", Flatau is even called to cure the demons. Excerpt from Singer's story reads: "The word soon spread through Krochmalna Street and the surrounding streets that a dybbuk had settled in Tzeitel's ear, and that it chanted Torah ... A Warsaw nerve specialist became interested in the case – Dr. Flatau, who was famous not only in Poland, but [also] in all Europe and maybe in America, too. And an article about the case appeared in a Yiddish newspaper. The author borrowed its title from Tolstoy's play The power of darkness." Medical practice In addition to his scientific work, he had a