Joseph Lyman DeRisi is an American biochemist, specializing in molecular biology, parasitology, genomics, virology, and computational biology. Early life and education DeRisi was raised in Carmichael, California, where he graduated from Del Campo High School. He received a B.A. in Biochemistry and Molecular Biology in 1992 from the University of California, Santa Cruz. DeRisi earned his Ph.D. in Biochemistry from Stanford University in 1999. Working in the laboratory of Patrick O. Brown, he developed methods for the production and use of DNA microarrays in molecular biology, and his thesis was a genome-wide expression analysis of the budding yeast S. cerevisiae. Upon graduation, DeRisi accepted a position as a Sandler Fellow at the University of California San Francisco. Career Joseph DeRisi is a co-president of the Chan Zuckerberg Biohub, and Chair of the Department of Biochemistry and Biophysics at the University of California, San Francisco (UCSF) with a joint appointment at the California Institute for Quantitative Biosciences (QB3). He is a former Howard Hughes Medical Institute (HHMI) Investigator. DeRisi's best-known achievements are printing the first whole genome expression array, performing the first broad analysis of differential gene expression in cancer cells, profiling gene expression throughout the lifecycle of the malaria-causing protozoan Plasmodium falciparum, his discovery of the SARS virus, and pioneering virus discovery using gene hybridization array and DNA sequencing technologies. DeRisi uses microarrays extensively in his work, and has designed and built both hardware and software for microarrays. He is a proponent of open access to microarray technology, and maintains a website with software and protocols for microarray operations. He is also a proponent of open access publishing, and has publications in the Public Library of Science journals. DeRisi has identified putative disease-causing viruses in humans (cancer, SARS, other respiratory infections, paraneoplastic encephalitis, etc.), and animals ranging from parrots and cockatiels to honeybees and boa constrictors. He and a research partner, Don Ganem, have identified a parasite, Nosema ceranae, that appears to be responsible for colony collapse among honeybees. He has also de-bunked the relation of viruses to certain subsets of human cancer. Perhaps most relevant to contemporary global health, based on extensive characterization of the malaria-causing pathogen, Plasmodium falciparum, DeRisi's group has developed profoundly promising candidate drugs to cure malaria. In 2004 DeRisi was named a MacArthur fellow (the "Genius" award), in 2008 was awarded the 14th Annual Heinz Award for Technology, the Economy, and Employment, in 2013 was