by Indians and ordered to return by the viceroy. After receiving some concessions, they returned to Mexico City. In 1570 the viceroy personally led an expedition against the Indian tribes that had been devastating the interior, but he did not give into demand for total war against the Chichimeca. He established presidios at Ojuelos and Portezuelos, on the road to Zacatecas. He founded the Villa de San Felipe (Guanajuato) and many other towns and villages, as well as colleges and convents. In 1573 he began the construction of the Cathedral of Mexico City. Enríquez brought medical attention to the unprotected and helped those in critical conditions. He established hospitals in the city to treat the victims of a terrible epidemic (thought to be chicken pox or varicella) that left 3,000 people dead. He published regulations in which the social protection of the Indians was guaranteed against their Spanish patrons, and a fair salary was assured for those who worked as peasants and farmers. Establishment of the Inquisition in New Spain During the government of Enríquez de Almanza, the Holy Office of the Inquisition (Tribunal del Santo Oficio) was formally established in New Spain; it was simultaneously established in Peru. Pedro Moya de Contreras, the first inquisitor in New Spain, arrived in 1571. Composed of a group of high-ranking bishops and sometimes led by the archbishop of Mexico City, the Inquisition had special instructions to oversee and control the religious practices of Spaniards and non-indigenous residents in the territory, and to eradicate any crypto-Jewish communities (judaizantes), as well as any Protestants. Indians were excluded from its jurisdiction. This religious court became quite active. The first to be tried by the Inquisition in the Indies were two Englishmen and an Irishman, burnt at the stake in Mexico City April 15, 1574 for "Lutheran heresies". An estimated 200 people were tried in 1574, the year in which the first Autos de Fe were held. Most of these 200 people were burnt alive in public plazas or tortured to death in secret dungeons, both scattered throughout what is now downtown Mexico City. The viceroy was required to attend these ceremonies. Viceroy of Peru King Philip II of Spain received outstanding comments about this viceroy, and he was aware of the obvious improvements made during his administration. In recognition of his labor, he was designated viceroy of Peru, Peru being a richer colony. Enríquez de