additional layer of neuron-glial cells is being added to Blue Brain Project models to improve functionality of the system. In 2017, Blue Brain Project discovered that neural cliques connected to one another in up to eleven dimensions. The project's director suggested that the difficulty of understanding the brain is partly because the mathematics usually applied for studying neural networks cannot detect that many dimensions. The Blue Brain Project was able to model these networks using algebraic topology. In 2018, Blue Brain Project released its first digital 3D brain cell atlas which, according to ScienceDaily, is like "going from hand-drawn maps to Google Earth", providing information about major cell types, numbers, and positions in 737 regions of the brain. In 2019, Idan Segev, one of the computational neuroscientists working on the Blue Brain Project, gave a talk titled: "Brain in the computer: what did I learn from simulating the brain." In his talk, he mentioned that the whole cortex for the mouse brain was complete and virtual EEG experiments would begin soon. He also mentioned that the model had become too heavy on the supercomputers they were using at the time, and that they were consequently exploring methods in which every neuron could be represented as an artificial neural network (see citation for details). In 2022, scientists at the Blue Brain Project used algebraic topology to create an algorithm, Topological Neuronal Synthesis, that generates a large number of unique cells using only a few examples, synthesizing millions of unique neuronal morphologies. This allows them to replicate both healthy and diseased states of the brain. In a paper Kenari et al. were able to digitally synthesize dendritic morphologies from the mouse brain using this algorithm. They mapped entire brain regions from just a few reference cells. Since it is open source, this will enable the modelling of brain diseases and eventually, the algorithm could lead to digital twins of brains. Software The Blue Brain Project has developed a number of software to reconstruct and to simulate the mouse brain. Blue Brain Nexus Blue Brain Nexus is a data integration platform which uses a knowledge graph to enable users to search, deposit, and organise data. It stands on the FAIR data principles to provide flexible data management solutions beyond neuroscience studies. It is an open source software and available for everyone on GitHub. BluePyOpt BluePyOpt is a tool that is used to build