she arranged the meeting, because she had recommended Nagra for the role of the new Indian character in ER during a conversation with her friend Wells. Not long after the meeting, Nagra signed a one-year contract that included an option for three additional years. Despite her new status, Nagra said, "I don't think Hollywood has changed me at all. The first thing I did when I arrived was buy chapati flour and lentils." Nagra made her first appearance on ER on 25 September 2003, in the tenth-season premiere titled "Now What?" as Neela Rasgotra, a new Yale-educated Anglo-Indian medical student at County General Hospital. Wells adapted the role to suit Nagra, so she could use her own English accent while working. Nagra appeared in twenty-one of the season's twenty-two episodes, including the twelfth episode titled "NICU" and the seventeenth episode titled "The Student", episodes in which her character played a central role. Noah Wyle, announcing his departure from the series in 2004, described Nagra as "the future" of ER, and the media concurred, anointing her as one of the show's "golden girls". In October 2008, following the departures of Goran Visnjic, Maura Tierney, and Mekhi Phifer, Nagra became the longest-serving cast member and lead actor of ER and remained so until the series concluded with season 15: episode 22, the two-hour series finale titled "And in the End..." which aired on 2 April 2009. When Nagra finished filming the eleventh season of ER in 2005, she returned to her native Leicester to star in Love in Little India directed by Amit Gupta. She was nominated in 2006 for an Asian Excellence Award, in the category of Outstanding Female Television Performance, for her work in ER, and won the award the following year. Nagra was awarded the Honorary Degree of Doctors of Letters by the University of Leicester on 11 July 2007. In 2008, Nagra voiced Cassandra in the DC animated film Batman: Gotham Knight. Later, she co-starred as Dr Lucy Banerjee in the Fox science fiction drama series Alcatraz which ran for one season from 16 January to 26 March 2012. Nagra starred as CIA agent Meera Malik in the first season of the NBC crime drama series The Blacklist from 2013 to 2014. In 2016, Nagra joined the second season of British arctic psychological thriller Fortitude. In 2018, Nagra joined the second season of the Netflix web television series