APFA may refer to: Association for the Protection of Fur-Bearing Animals, an animal welfare organization based in Canada Association of Professional Financial Advisers, a trade association made up of financial advisers across the United Kingdom Association of Professional Flight Attendants, a transportation trade union in the United States Midwest Football League (1935–1940) (previously the American Professional Football Association), a minor professional American football league National Football League (previously the American Professional Football Association), a professional American football league See also Professional Footballers Australia, or PFA, sometimes mistakenly referred to as APFA