Ebbe Curtis Hoff (August 12, 1906 in Rexford, Kansas – February 17, 1985 in Richmond, Virginia) was chairman of the Department of Neurological Science at the Medical College of Virginia, founding Dean, School of Graduate Studies and founding director of the Virginia Division of Substance Abuse. He earned a bachelor's degree in Zoology summa cum laude at the University of Washington in 1928 and a Doctor of Philosophy in physiology from St Catherine's College, Oxford in 1932 where he studied neurophysiology, writing his thesis on the theory of the synapse under Nobel Prize laureate Sir Charles Sherrington. From 1932 to 1936 he held the Alexander Browne Coxe research fellowship in the School of Medicine at Yale University, where he taught and conducted neurophysiologic research. He also taught at Sarah Lawrence College. Returning to Oxford he attended medical school (United Kingdom) earning his Bachelor of Medicine and Surgery, Doctor of Medicine and Master of Surgery degrees and the London Hospital Medical College, finishing in 1940. Narrowly avoiding the Blitz, he did higher risk home deliveries with midwives. Once again at Yale, he was part of the Yale Aeromedical Research Unit under John Farquhar Fulton, Chair of Physiology, coauthoring publications on aviation medicine. During World War II, he was commissioned Lt. Commander in the Medical Corps of the United States Navy as a flight surgeon and became a leading authority on diving hazards and precautions, as well as submarine and aviation medicine. He authored the first comprehensive text on compressed air diving and submarine medicine. He participated in developing the modified G-Suit design adopted for US Navy pilots. He took part in unsuccessful attempts to develop a shark repellent. He also served as a Naval Attaché at the American Embassy, London. Because he was fluent in German, after the victory in Europe he spent time in Berlin recruiting scientist. He left active military service with the rank of Commander in 1946 but remained in the Naval Reserve. After the war, he began teaching as Professor of Physiology at the Medical College of Virginia in 1946. He was the first director of the Division of Alcohol Studies and Rehabilitation of the Virginia Health Department, founded in 1948. He continued teaching, research, administration and clinical work at the alcoholic treatment clinic housed at MCV. In collaboration with his wife Phebe Hoff, he edited a multi-volume history of Preventive Medicine in World War II, which