and activation of separase is vital for proper anaphase. Overall, securin and separase act in an anaphase-regulating network. Figure 4 depicts a potential network diagram. References External links Video by David Morgan explaining action of securin and separin (in MP4 format): http://media.hhmi.org/ibio/morgan/morgan_3.mp4 and in other formats: Controlling the Cell Cycle: Anaphase Onset Mitosis Cell biology