A medical illustration is a form of biological illustration that helps to record and disseminate medical, anatomical, and related knowledge. History Medical illustrations have been made possibly since the beginning of medicine in any case for hundreds (or thousands) of years. Many illuminated manuscripts and Arabic scholarly treatises of the medieval period contained illustrations representing various anatomical systems (circulatory, nervous, urogenital), pathologies, or treatment methodologies. Many of these illustrations can look odd to modern eyes, since they reflect early reliance on classical scholarship (especially Galen) rather than direct observation, and the representation of internal structures can be fanciful. An early high-water mark was the 1543 CE publication of Andreas Vesalius's De Humani Corporis Fabrica Libri Septum, which contained more than 600 exquisite woodcut illustrations based on careful observation of human dissection. Since the time of the Leonardo da Vinci and his depictions of the human form, there have been great advancements in the art of representing the human body. The art has evolved over time from illustration to digital imaging using the technological advancements of the digital age. Berengario da Carpi was the first known anatomist to include medical illustration within his textbooks. Gray's Anatomy, originally published in 1858, is one well-known human anatomy textbook that showcases a variety of anatomy depiction techniques. In 1895, Konrad Roentgen, a German physicist discovered the X-Ray. Internal imaging became a reality after the invention of the X-Ray. Since then internal imaging has progressed to include ultrasonic, CT, and MRI imaging. As a profession, medical illustration has a more recent history. In the late 1890s, Max Brödel, a talented artist from Leipzig, was brought to The Johns Hopkins School of Medicine in Baltimore to illustrate for Harvey Cushing, William Halsted, Howard Kelly, and other notable clinicians. In addition to being an extraordinary artist, he created new techniques, such as carbon dust, that were especially suitable to his subject matter and then-current printing technologies. In 1911 he presided over the creation of the first academic department of medical illustration, which continues to this day. His graduates spread out across the world, and founded a number of the academic programs listed below under "Education". Notable medical illustrators include Max Brödel and Dr. Frank H. Netter. For an online inventory of scientific illustrators including currently already more than 1000 medical illustrators active 1450-1950 and specializing in anatomy, dermatology and embryology, see the Stuttgart Database of Scientific Illustrators