SINEs (short interspersed repetitive elements) 7SK RNA Several microRNAs Several small nucleolar RNAs Several gene regulatory antisense RNAs Role in DNA repair RNA polymerase III appears to be essential for homologous recombinational repair of DNA double-strand breaks. RNA polymerase III catalyzes formation of a transient RNA-DNA hybrid at double strand breaks, an essential intermediate step in homologous recombination mediated double-strand break repair. This step protects the 3’ overhanging DNA strand from degradation. After the transient RNA-DNA hybrid intermediate is formed the RNA strand is replaced by the RAD51 protein which then catalyzes the ssDNA invasion step of homologous recombination. See also RNA polymerase References Gene expression Proteins