It will not rain for 12 years in that area and everything including metal and earth becomes poisoned. In the epic Mahabharata, it is said that the weapon manifest with the four heads of Brahma as its tip. In the Mahabharata, Agnivesha, Karna, Drona, Ashwatthama and Arjuna possessed the knowledge to invoke this weapon. Brahmanda astra: This is the most powerful weapon of Brahma. It was first used by sage Vashishtha against Vishwamitra's (who was King Vishwarath at that time) Brahmashirsha, as only Brahmanda astra can stop Brahmashirsha astra, it was also used by sage Piplad against Shani to avenge his father's death.In the epic Mahabharata, it is said that the weapon manifest with the all five heads of Brahma as its tip.Brahma earlier lost his fifth head when he fought with Siva.This weapon is said to possess the power to destroy entire solar system or brahmand, the 14 realms according to Hindu cosmology. In some texts it is called Brahma-dhanda astra, the weapon created by Saptarishi's to counter any weapon ever created, even that of Trimurti's. The rishi of this weapon is Para Brahman. It is stated to be the most difficult astra to obtain. Capable of destroying entire universe in a blink of an eye. Vishvamitra used all kinds of divine weapons against sage Vashistha, even Pashupatastra, but the Brahma-dhanda astra of Vashistha neutralized and swallowed all astra (weapon) of Vishwamitra proving that Brahma-dhanda astra is the most powerful of all astras. Karna, Bhisma and Drona were the only warriors in the Mahabharata who possessed the knowledge of this weapon. Pashupatastra: In Hinduism, it is considered that Pashupatastra is the most devastating weapon, as it is the weapon of the consort of the God head Mahadeva, i.e. Mahakali. Mahadeva literally means "Highest of all gods" and Mahakali means "Goddess who is beyond time". This weapon was granted to Arjuna by Shiva. It is the most destructive and foreboding weapon. It was first used by Shiva for the destruction of tripura. It is capable of destroying entire multiverse. In the Ramayana, Vishvamitra possessed this mighty weapon. In the Mahabharata, only Arjuna possessed this weapon. Narayanastra: Invincible and painful, this astra is unconquerable except by total submission, this astra was used by Krishna against Shiva, when Shiva was fighting on behalf of the evil Banasura, when Shiva charged his personal Pashupatastra on Krishna, Krishna used this to make Shiva fall