Mississippi Highway 7 (MS 7) runs generally north–south from the Tennessee state line in Benton County to Belzoni, Mississippi. It travels approximately , serving Humphreys, Leflore, Carroll, Grenada, Yalobusha, Lafayette, Marshall, and Benton counties while serving several points of interest, including Florewood River Plantation State Park, the University of Mississippi, and Wall Doxey State Park. MS 7 runs nearly parallel to the rarely used Mississippi Central Railroad. Route description MS 7 begins in the Mississippi Delta region in Humphreys County at an intersection between US 49W, MS 3, and MS 12 in Belzoni. It heads east as a two-lane highway along 1st Street into downtown, where it turns north along Hayden Street to pass through neighborhoods before leaving Belzoni. The highway curves to the north east as it passes through farmland, paralleling the Yazoo River as it passes through the Sky Lake Wildlife Management Area. Throughout this area, MS 7 crosses over several oxbow lakes and bayous, both of which represent former alignments of the Yazoo River. MS 7 now enters Leflore County. MS 7 now travels through the community of Swiftown and the town of Morgan City, where it passes just a few miles west of Mathews Brake National Wildlife Refuge. The highway now passes through Quito before going straight through downtown Itta Bena, with it entering town and immediately making a right turn onto Lakeside Street, then left onto Basket Street, which turns into Schley Street in downtown. MS 7 now comes to an intersection with US 82, which it becomes concurrent with and they head east as four-lane divided highway to enter the Greenwood city limits, immediately passing along the northern edge of Florewood River Plantation State Park. US 49E joins the concurrency and they cross a floodway (which dumps water from the Tallahatchie River into the Yazoo) to enter a business district. US 49E/US 82/MS 7 turn southward to bypass downtown, and cross a bridge over the Yazoo River, before curving back eastward to come to a large interchange with Main Street (unsigned MS 743) at the south side of downtown, where US 49E splits off. US 82/MS 7 continue east to pass through neighborhoods, where it has a partial interchange with MS 744 and an intersection with MS 430, before MS 7 splits off as a two-lane at the eastern edge of town and heads north to leave Greenwood. MS 7 crosses over Big Sand