The Wayne State University School of Medicine (WSUSOM) is the medical school of Wayne State University, a public research university in Detroit, Michigan. It enrolls more than 1,500 students in undergraduate medical education, master's degree, Ph.D., and M.D.-Ph.D.. WSUSOM traces its roots through four predecessor institutions since its founding in 1868. The school's faculty consists of numerous local physicians, many who are members of the Wayne State University Physician Group, and provide care at eleven affiliated hospitals, clinics and training sites throughout the area. Although the school's faculty offer expertise in virtually all medical fields, the institution's areas of research emphasis include cancer, women's and children's health, neuroscience and population studies. History The Detroit Medical College was founded in 1868 in a building on Woodward Avenue. The Michigan College of Medicine was incorporated in 1879 and offered classes in the former Hotel Hesse at the intersection of Gratiot Avenue, Madison Avenue and St Antoine Street. In 1885, the two schools merged to form the Detroit College of Medicine and occupied the former Michigan College of Medicine building. The college was reorganized and refinanced as the Detroit College of Medicine and Surgery in 1913, and five-years later, came under control of the Detroit Board of Education. In 1933, the Board of Education joined the Detroit College of Medicine and Surgery with the colleges of Liberal Arts, Education, Engineering, Pharmacy, and the Graduate School to form an institution of higher education called the Colleges of the City of Detroit. This was renamed Wayne University in 1934 and became a state-chartered institution, Wayne State University, in 1956. Professors at the school provided the "first evidence that glucose is a major stimulant on insulin secretion and, while an increase in the concentration of blood glucose stimulates the secretion of insulin, a decrease inhibits it and, in addition, stimulates the secretion of a blood-sugar raising factor (glucagon) by the pancreas." Subsequent experiments contributed substantially to the establishment of glucagon as a "second pancreatic hormone." The first successful open heart surgery was performed at the Detroit Medical Center by Wayne State University physician Dr. Forest Dodrill on patient Henry Opitek. He used a machine developed by himself and researchers at General Motors, the Dodrill-GMR, considered to be the first operational mechanical heart used while performing open heart surgery. Wayne State University School of Medicine is the academic affiliate of the Barbara Ann Karmanos Cancer Institute, one