Town, Uryū visits his father, Ryūken, who offers to restore his Quincy powers on the condition that Uryū will never work with Soul Reapers again. Uryū agrees and regains his powers, but soon discovers that Orihime has been captured by Aizen. He, Ichigo and Chad arrive to Hueco Mundo to rescue her. Upon meeting Rukia and Renji in Hueco Mundo, their group splits up upon arrival. Uryū defeats Cirucci Sanderwicci, before meeting up with Renji to fight Szayelaporro Grantz. Before being defeated and despite the aid from Nel's Fracciónes, Mayuri indirectly comes to their aid. After his injuries are healed, Uryū holds Yammy at bay, before protecting Orihime from Ulquiorra Shiffer. He tries to stop the Hollowified Ichigo from attacking Ulquiorra, and is attacked himself, but is saved by Ulquiorra, who dies shortly afterwards. He remained with Orihime for the duration of the final battle against Aizen. Seventeen months after Aizen's defeat and the subsequent loss of Ichigo's Soul Reaper powers, Uryū is ambushed by Kūgo Ginjō. Uryū arrives in time and tells Ichigo not to trust Ginjo. Uryū helps the Soul Reapers defeat Ginjo and other members of Xcution. The Wandenreich, a group of Quincies take over Hueco Mundo culminating in the advent of the Quincy Blood War. Uryū refuses to aid everyone, while Ichigo goes on a rescue mission. Uryū is recruited by Yhwach at Silbern and the other Sternritters, and learns that he has been named the Wandenreich leader's heir. Ywhach proceeds to bestow Uryū with an 'A' Schrift in a private ceremony, making him a Sternritter while explaining to Uryū that he survived the effects of Auswählen compared to other impure Quincies, due to an unforeseen power within him, thus, convincing Yhwach to appoint him as his successor. Despite learning that Auswählen is the cause of his mother's death, Uryū accompanies Yhwach to the Soul Society for an invasion along with the Sternritters. After Yhwach had absorbed the Soul King and remodeled the entire Soul King Palace, Uryū was assigned to the Schutzstaffel. However, during the climax of the series of battles, Haschwalth having deduced his true intentions to wipe out Wahrwelt itself, Uryū reveals his reasons to Ichigo and his friends for coming to the Soul Society were because he is a Quincy and that only his spiritual pressure can activate the chips that he extracted from the sanrei glove, which he placed around the