Bones is an American crime procedural comedy-drama television series created by Hart Hanson for Fox. It premiered on September 13, 2005, and concluded on March 28, 2017, airing for 246 episodes over 12 seasons. The show is based on forensic anthropology and forensic archaeology, with each episode focusing on a Federal Bureau of Investigation (FBI) case file concerning the mystery behind human remains brought by FBI Special Agent Seeley Booth (David Boreanaz) to Temperance "Bones" Brennan (Emily Deschanel), a forensic anthropologist. It also explores the personal lives of the characters. The rest of the main cast includes Michaela Conlin, T. J. Thyne, Eric Millegan, Jonathan Adams, Tamara Taylor, John Francis Daley, and John Boyd. The series is very loosely based on the life and novels of forensic anthropologist Kathy Reichs, who also produced the show. Its title character, Temperance Brennan, is named after the protagonist of Reichs' crime novel series. In the Bones universe, Brennan writes successful mystery novels featuring a fictional forensic anthropologist named Kathy Reichs. Bones is a joint production by Josephson Entertainment and Far Field Productions in association with 20th Century Fox Television and syndicated by 20th Television. The series is the longest-running one-hour drama series produced by 20th Century Fox Television. Premise The premise of the show is an alliance between forensic anthropologist Temperance "Bones" Brennan and FBI Special Agent Seeley Booth. Brennan is the central character and team leader of the fictional Jeffersonian Institute Medico-Legal Lab, a federal institution that collaborates with the FBI. This reflects the historical relationship between the FBI and scientists of the Smithsonian Institution. Set in Washington, D.C., the show revolves around solving federal legal cases by examining the human remains of possible murder victims. While the majority of their cases take place in the surrounding Washington metropolitan area, they have been called in to investigate cases in other states and sometimes countries, including Iran and Mexico. Brennan and her team provide scientific expertise, and Booth provides FBI criminal investigation techniques. In addition to the prospective murder cases featured in each episode, the series explores the backgrounds and relationships of its characters, particularly the romantic tension between Brennan and Booth. An important ongoing dynamic between Brennan and Booth is their disagreement about science and faith. Brennan argues for science, evidence, and atheism. Booth argues for intuition, faith, and God. Their relationship is highlighted by the introduction of Lance Sweets, an FBI